7235744

Tocris™ MPro N3

Coronavirus Mpro inhibitor

Manufacturer: Fischer Scientific

CAS Number: 884650-98-0

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Chemical Name or Material

N-[(5-Methyl-3-isoxazolyl)carbonyl]-L-alanyl-L-valyl-N-[(1 S,2 E)-4-oxo-1-[[(3 S)-2-oxo-3-pyrrolidinyl]methyl]-4-(phenylmethoxy)-2-buten-1-yl]-L-leucinamide

Target

Additional Synthetic Protease Inhibitors

Purity

0.98

CAS

884650-98-0

Molecular Formula

C35H48N6O8

Other Options

Image Product Name Manufacturer Price Range
72-302-5
Tocris™ MPro N3
Fischer Scientific ₹ 73,496.04
72-305
Tocris™ MPro N3
Fischer Scientific ₹ 17,668.14

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Description

  • MPro N3 is a coronavirus main protease (Mpro) inhibitor (respective IC50 values are 2.7, 4 and 8.8 μM for MHV-A29, HCoV-229E and FOPV replication in vitro )
  • Inhibits viral cell infection in an MHV plaque reduction assay
  • Also inhibits SARS-CoV-2 viral cell entry in a plaque reduction assay (IC50 = 16.8 μM).

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Chemical Name or Material:
N-[(5-Methyl-3-isoxazolyl)carbonyl]-L-alanyl-L-valyl-N-[(1 S,2 E)-4-oxo-1-[[(3 S)-2-oxo-3-pyrrolidinyl]methyl]-4-(phenylmethoxy)-2-buten-1-yl]-L-leucinamide

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Molecular Formula:
C35H48N6O8

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