71-965-0

Tocris Bioscience™ Indinavir sulfate

Manufacturer: Tocris Bioscience™

CAS Number: 157810-81-6

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Pack Size SKU Availability Price
Each of 1 71-965-0-Each-of-1 In Stock ₹ 13,638.26

71-965-0 - Each of 1

₹ 13,638.26

In Stock

Quantity

1

Base Price: ₹ 13,638.26

GST (18%): ₹ 2,454.887

Total Price: ₹ 16,093.147

Chemical Name or Material

2,3,5-Trideoxy-N-[(1 S,2 R)-2,3-dihydro-2-hydroxy-1 H-inden-1-yl]-5-[(2 S)-2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-D-erythro-pentonamide sulfate

Quantity

50 mg

Molecular Formula

C36H47N5O4.H2SO4

CAS

157810-81-6

Target

HIV Protease Inhibitors

Purity

0.98

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Description

  • Indinavir sulfate is a potent and selective HIV protease inhibitor (Ki values are 0.52 and 3.3 nM for HIV-1 and HIV-2, respectively)
  • Indinavir stops the spread of the HIV-infected MT4 lymphoid cells at concentrations of 25-50 nM
  • Indinavir disrupts the ERK1/2 and p38 MAPK pathways and reduces both the level of functional eIF4F complex and rpS6 phosphorylation, which leads to a decrease in protein synthesis in mouse myocytes
  • In silico docking models predict potential as an inhibitor of SARS-CoV-2 3CLpro.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Tocris Bioscience™

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Chemical Name or Material:
2,3,5-Trideoxy-N-[(1 S,2 R)-2,3-dihydro-2-hydroxy-1 H-inden-1-yl]-5-[(2 S)-2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-D-erythro-pentonamide sulfate

Quantity:
50 mg

Molecular Formula:
C36H47N5O4.H2SO4

CAS:
157810-81-6

Target:
HIV Protease Inhibitors

Purity:
0.98

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50 rxn

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Chemical Name or Material:
8-Chloro-11-(4-ethylpiperazin-1-yl)-4-fluoro-5 H-dibenzo[b,e][1,4 ]diazepine

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C19H20ClFN4

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