78-135
Tocris Bioscience™ LL-K9-3
Manufacturer: Tocris Bioscience™
CAS Number: 2809353-52-2
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 78-135-Each-of-1 | In Stock | ₹ 33,325.62 |
78-135 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,325.62
GST (18%): ₹ 5,998.612
Total Price: ₹ 39,324.232
Chemical Name or Material
N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-1-[[2-[[2-[[(1 R,2 S,5 R)-5-methyl-2-(1-methylethyl)cyclohexyl]oxy]acetyl]amino]ethyl]sulfonyl]-4-piperidinecarboxamide
Quantity
5 mg
Molecular Formula
C31H49N5O6S3
CAS
2809353-52-2
Target
Active Degraders
Purity
0.98
Related Products
Description
- LL-K9-3 is a selective hydrophobic tagging technologies (HyT)-based Degrader of the CDK9-cyclin T1 complex (DC50 values are 589 and 662 nM for cyclin T1 and CDK9, respectively)
- It comprises a CDK9 inhibitor, SNS 032 (Cat
- No
- 4075), joined by a glycol linker to hydrophobic tag
- LL-K9-3 exhibits no degradation of other CDKs (CDK1, 2, 4, 5, 6, and 7)
- In 22RV1 cells
- LL-K9-3 reduces expression of androgen receptor (AR) and cMyc by inducing selective and synchronous degradation of CDK9 and cyclin T1.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-1-[[2-[[2-[[(1 R,2 S,5 R)-5-methyl-2-(1-methylethyl)cyclohexyl]oxy]acetyl]amino]ethyl]sulfonyl]-4-piperidinecarboxamide
Quantity: 5 mg
Molecular Formula: C31H49N5O6S3
CAS: 2809353-52-2
Target: Active Degraders
Purity: 0.98
Chemical Name or Material:
N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-1-[[2-[[2-[[(1 R,2 S,5 R)-5-methyl-2-(1-methylethyl)cyclohexyl]oxy]acetyl]amino]ethyl]sulfonyl]-4-piperidinecarboxamide
Quantity:
5 mg
Molecular Formula:
C31H49N5O6S3
CAS:
2809353-52-2
Target:
Active Degraders
Purity:
0.98
Chemical Name or Material: __
Quantity: 100 μg
Molecular Formula: __
CAS: __
Target: __
Purity: __
Chemical Name or Material:
__
Quantity:
100 μg
Molecular Formula:
__
CAS:
__
Target:
__
Purity:
__
Chemical Name or Material: 3-β-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzothiazin-2(3H)-one
Quantity: 10 mg
Molecular Formula: C15H15N3O5S
CAS: 1174063-74-1
Target: Fluorescent RNA Probes
Purity: 95%
Chemical Name or Material:
3-β-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzothiazin-2(3H)-one
Quantity:
10 mg
Molecular Formula:
C15H15N3O5S
CAS:
1174063-74-1
Target:
Fluorescent RNA Probes
Purity:
95%
Chemical Name or Material: (2 S,4 R)-1-(-2-(4-(4-(5-((Furan-2-ylmethyl)amino)-[1,2,4 ]triazolo[4,3-c]pyrimidin-8-yl)benzamido)butanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Quantity: 5 mg
Molecular Formula: C43H48N10O6S
CAS: 2688842-08-0
Target: Active Degraders
Purity: 0.98
Chemical Name or Material:
(2 S,4 R)-1-(-2-(4-(4-(5-((Furan-2-ylmethyl)amino)-[1,2,4 ]triazolo[4,3-c]pyrimidin-8-yl)benzamido)butanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Quantity:
5 mg
Molecular Formula:
C43H48N10O6S
CAS:
2688842-08-0
Target:
Active Degraders
Purity:
0.98