81-051-0
Tocris Bioscience™ CAF 382
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 81-051-0-Each-of-1 | In Stock | ₹ 17,267.72 |
81-051-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,267.72
GST (18%): ₹ 3,108.19
Total Price: ₹ 20,375.91
Chemical Name or Material
N-[5-[(5-Propan-2-yl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide trifluoroacetate
Target
CDKL5
Purity
0.98
Quantity
10 mg
Molecular Formula
C16H22N4O2S2.CF3CO2H
Related Products
Description
- CAF 382 is potent and selective CDKL5 (cyclin-dependent kinase-like 5) inhibitor (IC50 = 10 nM)
- Exhibits nearly 100-fold selectivity for CDKL5 over CDKL2, low inhibition for CDKL3 and CDKL4 (IC50 = 2.1-2.7 ?M), and no inhibition for CDKL1
- CAF 382 lacks GSK3β activity
- It causes a significant reduction in pSer222 EB2 at 5 nM without a change in total EB2 levels in rat primary cortical neuron cultures
- CAF 382 is an analog of SNS 032 (Cat
- No
- 4075).
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: N-[5-[(5-Propan-2-yl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide trifluoroacetate
Target: CDKL5
Purity: 0.98
Quantity: 10 mg
Molecular Formula: C16H22N4O2S2.CF3CO2H
Chemical Name or Material:
N-[5-[(5-Propan-2-yl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide trifluoroacetate
Target:
CDKL5
Purity:
0.98
Quantity:
10 mg
Molecular Formula:
C16H22N4O2S2.CF3CO2H
Chemical Name or Material: N-[5-[(5-Propan-2-yl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide trifluoroacetate
Target: CDKL5
Purity: 0.98
Quantity: 50 mg
Molecular Formula: C16H22N4O2S2.CF3CO2H
Chemical Name or Material:
N-[5-[(5-Propan-2-yl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide trifluoroacetate
Target:
CDKL5
Purity:
0.98
Quantity:
50 mg
Molecular Formula:
C16H22N4O2S2.CF3CO2H
Chemical Name or Material: __
Target: Fluorescent Probes
Purity: __
Quantity: 20 μg
Molecular Formula: __
Chemical Name or Material:
__
Target:
Fluorescent Probes
Purity:
__
Quantity:
20 μg
Molecular Formula:
__
Chemical Name or Material: 8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride
Target: Other Kinase Inhibitors
Purity: 0.98
Quantity: 10 mg
Molecular Formula: C26H29ClN6O3.3HCl
Chemical Name or Material:
8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride
Target:
Other Kinase Inhibitors
Purity:
0.98
Quantity:
10 mg
Molecular Formula:
C26H29ClN6O3.3HCl