56-756-910MG
MilliporeSigma™ Calbiochem™ Spautin-1
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 56-756-910MG-Each-of-1 | In Stock | ₹ 18,768.44 |
56-756-910MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 18,768.44
GST (18%): ₹ 3,378.319
Total Price: ₹ 22,146.759
Color
Off-white
Molecular Formula
C15H11F2N3
Solubility
DMSO
Form
Solid
Description
99% by HPLC
Formula Weight
271.26g/mol
Content And Storage
Protect from light
Quantity
10 mg
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Description
- A quinazolin compound that acts as a specific and potent inhibitor of autophagy and promotes Vps34 PI 3-kinase complex degradation by blocking the activity of USP 10 (IC50 = 580nM) and USP 13 (IC50 = 690nM) deubiquitinating enzymes
- However, it does not affect the lipid kinase activity of Vps34
- Also shown to reduce the level of cytoplasmic and nuclear p53
- Sensitizes breast cancer cell lines (BCAP37, MCF-7, and BT549) to apoptosis under conditions of nutritional deprivation
- Also shown to inhibit etoposide-induced cell death in Bax/Bak double knockout (DKO) cells
- Normal cell lines (e.g., MDCK cells) do not undergo autophagy in the presence of Spautin-1.
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Color: Off-white
Molecular Formula: C15H11F2N3
Solubility: DMSO
Form: Solid
Description: 99% by HPLC
Formula Weight: 271.26g/mol
Content And Storage: Protect from light
Quantity: 10 mg
Color:
Off-white
Molecular Formula:
C15H11F2N3
Solubility:
DMSO
Form:
Solid
Description:
99% by HPLC
Formula Weight:
271.26g/mol
Content And Storage:
Protect from light
Quantity:
10 mg
Color: __
Molecular Formula: __
Solubility: __
Form: __
Description: Voltage-gated Potassium Channel Blockers
Formula Weight: __
Content And Storage: Store at -20°C
Quantity: 100 μg
Color:
__
Molecular Formula:
__
Solubility:
__
Form:
__
Description:
Voltage-gated Potassium Channel Blockers
Formula Weight:
__
Content And Storage:
Store at -20°C
Quantity:
100 μg
Color: __
Molecular Formula: __
Solubility: __
Form: __
Description: __
Formula Weight: __
Content And Storage: 15°C to 30°C
Quantity: 1 kg
Color:
__
Molecular Formula:
__
Solubility:
__
Form:
__
Description:
__
Formula Weight:
__
Content And Storage:
15°C to 30°C
Quantity:
1 kg
Color: __
Molecular Formula: __
Solubility: __
Form: __
Description: __
Formula Weight: __
Content And Storage: 15°C to 30°C
Quantity: 250 g
Color:
__
Molecular Formula:
__
Solubility:
__
Form:
__
Description:
__
Formula Weight:
__
Content And Storage:
15°C to 30°C
Quantity:
250 g