Anti-PIK3R1 antibody produced in rabbit

Description

• Immunogen: Phosphatidylinositol 3-kinase regulatory subunit α recombinant protein epitope signature tag (PrEST)
• Application: All Prestige Antibodies®Powered by Atlas Antibodies is developed and validated by the Human Protein Atlas (HPA) project . Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. We also provide Prestige Antibodies® protocols and other useful information.
• Biochem/physiol Actions: PIK3R1 (phosphoinositide-3-kinase, regulatory subunit 1) gene encodes the 85kDa regulatory subunit of phosphatidylinositol 3-kinase. The enzyme contains a 110kDa catalytic subunit that phosphorylates inositol ring of phosphatidylinositol at the 3′ position. It is essential for the insulin-stimulated increase in glucose uptake and glycogen synthesis in tissues that are insulin-sensitive. Mutation in this gene causes SHORT syndrome characterized by short stature, hyperextensibility of joints, ocular depression, Rieger anomaly and teething delay.
• Features and Benefits: Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.Every Prestige Antibody is tested in the following ways:IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.Protein array of 364 human recombinant protein fragments.
• Linkage: Corresponding Antigen APREST78872
• Physical form: Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide
• Legal Information: Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany
• Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.