HPA015313

Anti-NDRG4 antibody produced in rabbit

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Manufacturer: Sigma Aldrich

Synonym(S): Anti-Brain development-related molecule 1, Anti-Protein NDRG4, Anti-SMAP-8, Anti-Vascular smooth muscle cell-associated protein 8

Select a Size

Pack Size SKU Availability Price
100 μL HPA015313-100-μL In Stock ₹ 48,995.40

HPA015313 - 100 μL

₹ 48,995.40

In Stock

Quantity

1

Base Price: ₹ 48,995.40

GST (18%): ₹ 8,819.172

Total Price: ₹ 57,814.572

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

product line

Prestige Antibodies® Powered by Atlas Antibodies

form

buffered aqueous glycerol solution

species reactivity

human

enhanced validation

orthogonal RNAseqrecombinant expressionLearn more about Antibody Enhanced Validation

Related Products

Img

Sigma Aldrich

HPA009178

Prestige Antibodies® Powered by Atl...

Img

Sigma Aldrich

HPA009285

Ab1, Prestige Antibodies® Powered b...

Img

Sigma Aldrich

HPA010553

Prestige Antibodies® Powered by Atl...

Img

Sigma Aldrich

HPA011216

Prestige Antibodies® Powered by Atl...

Img

Sigma Aldrich

HPA012024

Prestige Antibodies® Powered by Atl...

Img

Sigma Aldrich

HPA012122

Prestige Antibodies® Powered by Atl...

Img

Sigma Aldrich

HPA012285

Prestige Antibodies® Powered by Atl...

Img

Sigma Aldrich

HPA012750

Prestige Antibodies® Powered by Atl...

Description

  • General description: NDRG4 (N-myc downstream regulated gene 4) is a member of the four protein family called NDRG. This protein, along with NDRG2 makes up a subfamily. This gene is localized to human chromosome 16q21-q22.3, is composed of seventeen exons, and spans 26kb. Alternative splicing gives rise to three isoforms called, NDRG4-B, NDRG4-Bvar, and NDRG4-H. Its expression is restricted to brain and heart.
  • Immunogen: Protein NDRG4 recombinant protein epitope signature tag (PrEST)
  • Application: Anti-NDRG4 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project . Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
  • Biochem/physiol Actions: NDRG4 (N-myc downstream regulated gene 4) is believed to act as a tumor suppressor gene, as it is inactivated in multiple cancer types. Studies suggest that this gene is involved in the survival of cell, and invasiveness of tumor cells. Homozygous variant in this gene might be the cause of infantile myofibromatosis (IM), which is characterized by benign tumor development in bone, viscera, skin and muscle. This gene is up-regulated in aggressive meningioma, and is involved in controlling cell proliferation, metastasis and angiogenesis in the same. It is methylated and silenced in colorectal cancer (CRC), and might have potential as a marker to determine CRC in sample stools. It is essential for cell growth and survival in glioblastoma and astrocytes.
  • Features and Benefits: Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.Every Prestige Antibody is tested in the following ways:IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.Protein array of 364 human recombinant protein fragments.
  • Linkage: Corresponding Antigen APREST72717
  • Physical form: Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide
  • Legal Information: Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany
  • Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

SAFETY INFORMATION

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Compare Similar Items

Show Difference

Img

Sigma Aldrich

HPA015313

Prestige Antibodies® Powered by Atl...


biological source:
rabbit

Quality Level:
100

conjugate:
unconjugated

antibody form:
affinity isolated antibody

antibody product type:
primary antibodies

clone:
polyclonal

product line:
Prestige Antibodies® Powered by Atlas Antibodies

form:
buffered aqueous glycerol solution

species reactivity:
human

enhanced validation:
orthogonal RNAseqrecombinant expressionLearn more about Antibody Enhanced Validation

Img

Sigma Aldrich

HPA015504

Prestige Antibodies® Powered by Atl...


biological source:
rabbit

Quality Level:
100

conjugate:
unconjugated

antibody form:
affinity isolated antibody

antibody product type:
primary antibodies

clone:
polyclonal

product line:
Prestige Antibodies® Powered by Atlas Antibodies

form:
buffered aqueous glycerol solution

species reactivity:
human

enhanced validation:
independentorthogonal RNAseqrecombinant expressionLearn more about Antibody Enhanced Validation

Img

Sigma Aldrich

HPA015536

Prestige Antibodies® Powered by Atl...


biological source:
rabbit

Quality Level:
100

conjugate:
unconjugated

antibody form:
affinity isolated antibody

antibody product type:
primary antibodies

clone:
polyclonal

product line:
Prestige Antibodies® Powered by Atlas Antibodies

form:
buffered aqueous glycerol solution

species reactivity:
mouse, human

enhanced validation:
RNAi knockdownLearn more about Antibody Enhanced Validation

Img

Sigma Aldrich

HPA015570

Prestige Antibodies® Powered by Atl...


biological source:
rabbit

Quality Level:
100

conjugate:
unconjugated

antibody form:
affinity isolated antibody

antibody product type:
primary antibodies

clone:
polyclonal

product line:
Prestige Antibodies® Powered by Atlas Antibodies

form:
buffered aqueous glycerol solution

species reactivity:
human

enhanced validation:
recombinant expressionLearn more about Antibody Enhanced Validation