Anti-MeCP2 antibody, Mouse monoclonal

Description

• General description: Methyl-CpG binding protein 2 (MeCP2) possesses a methyl-CpG-binding domain (MBD) and a transcriptional repression domain.
• Immunogen: synthetic peptide corresponding to the N-terminus (amino acids 15-30) of human MeCP2.
• Application: Monoclonal Anti-MeCP2 antibody has been used:in western blottingin immunoblottingin flow cytometryin immunohistofluorescencein immunocytochemistry
• Biochem/physiol Actions: MeCP2 (methyl-CpG binding protein 2) silences transcription by recruiting the histone deacetylase (HDAC) repressive machinery via recruitment of the Sin 3A corepressor, thus removing acetyl groups from histones and consequently, silencing genes.
• Physical form: Solution in 0.01 M phosphate buffered saline containing 15 mM sodium azide.
• Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.