Anti-CD34 Class I Antibody, clone B1-3C5

Description

• Specificity: This antibody belongs to CD34 (assigned by the Third International Workshop on Leukocyte Differentiation Antigens, Oxford, 1987; Hogg & Horton, 1987). It reacts with a 120kD glycoprotein found on progenitor cell populations in human bone marrow and foetal liver (Katz et al., 1985). This antigen is normally restricted to immature human haemopoietic precursor cells (Peschel & Koller, 1989). Cell reactivity (Tindle et al., 1985): Normal: No reaction with normal peripheral lymphocytes, granulocytes, monocytes, erythrocytes and platelets. Reacts with <4% of cells in normal bone marrow. Clinical: Reaction Acute myeloid leukemia (AML, M1 and M2) positive Null lymphoblastic leukemia (Null ALL) positive Common acute lymphoblastic leukemia (CALL) positive Myeloblastic and lymphoblastic crises of chronic granulocytic leukemia (CGL) positive Chronic myeloid leukemia (CML) negative T cell acute lymphoblastic leukemia (TALL) negative B cell acute lymphoblastic leukemia (BALL) negative Chronic lymphocytic leukemia (CLL) negative Cell lines: Reacts with early myeloblast line KG1. No reaction with null, B or T lymphoid, erythroid or later myeloid cell lines.
• Immunogen: KG1 human acute myelogenous cell line.
• Application: Detect CD34 Class I using this Anti-CD34 Antibody (Class 1), clone B1-3C5 validated for use in FC & IF.
• Physical form: Format: Purified
• Storage and Stability: For prolonged periods, store below -20°C in undiluted aliquots. AVOID REPEATED FREEZE/THAW CYCLES. Product stable for 6 months when stored as directed. WARNING: The monoclonal reagent solution contains 0.1% sodium azide as a preservative. Due to potential hazards arising from the build up of this material in pipes, spent reagent should be disposed of with liberal volumes of water.
• Legal Information: CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
• Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.