SAB4200782
Anti-Tenascin antibody, Mouse monoclonal
clone BC-24, purified from hybridoma cell culture
Manufacturer: Sigma Aldrich
Synonym(S): Anti-Cytotactin, Anti-GMEM, Anti-GP 150-225, Anti-Glioma-associated-extracellular matrix antigen, Anti-Hexabrachion, Anti-JI, Anti-Myotendinous antigen, Anti-Neuronectin, Anti-TN, Anti-Tenascin-C (TN-C)
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 μL | SAB4200782-100-μL | In Stock | ₹ 55,877.40 |
SAB4200782 - 100 μL
In Stock
Quantity
1
Base Price: ₹ 55,877.40
GST (18%): ₹ 10,057.932
Total Price: ₹ 65,935.332
biological source
mouse
Quality Level
200
antibody form
purified from hybridoma cell culture
antibody product type
primary antibodies
clone
BC-24, monoclonal
form
buffered aqueous solution
species reactivity
human
concentration
~1.0 mg/mL
technique(s)
ELISA: suitableflow cytometry: suitableimmunoblotting: suitableimmunohistochemistry: 5-10 μg/mL using pronase-retrieved formalin-fixed, paraffin-embedded human tonsil sections
isotype
IgG1
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Description
- General description: Monoclonal Anti-Tenascin (mouse IgG1 isotype) is derived from the BC-24 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from a mouse immunized with human tenascin. Tenascin-C (TN-C) is also known as Hexabrachion, Cytotactin, Neuronectin (NEC1). It is a high molecular mass extracellular matrix glycoprotein. Human tenascin is a disulfide-linked hexamer composed of 3 subunits of 190, 200, and 220 kDa.
- Immunogen: Human tenascin
- Application: Anti-Tenascin antibody has been used:in immunoblottingin Immunohistochemistryin flow cytometryin enzyme linked immunosorbent assay(ELISA)for blocking tenascin-C proliferating activity
- Biochem/physiol Actions: Tenascin-C (TN-C) functions in cell adhesion, fibroblast migration, and other processes related to tissue remodeling and wound healing. It has been proposed that actively growing, migrating and differentiating epithelial sheets can produce factors such as (Transforming growth factor beta) TGF-β to stimulate tenascin expression. Neo-expression or increased expression of tenascin has been found in the stroma of various tumors and during normal tissue repair. Intracytoplasmic tenascin immunoreactivity has been detected in malignant melanomas and in lung carcinomas, and it serves as a marker of stromal element proliferation in invasive breast carcinomas. High-molecular mass tenascin isoform plays a role in generating a permissive environment for proliferation, invasion, and metastasis of neoplastic epithelial cells. Human tenascin contains an Arg-Gly-Asp (RGD) sequence which may function in cell adhesion and mediates cell attachment through an RGD-dependent integrin receptor.
- Physical form: Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as a preservative.
- Other Notes: This product is for R&D use only, not for drug, household, or other uses.
SAFETY INFORMATION
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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biological source: mouse
Quality Level: 200
antibody form: purified from hybridoma cell culture
antibody product type: primary antibodies
clone: BC-24, monoclonal
form: buffered aqueous solution
species reactivity: human
concentration: ~1.0 mg/mL
technique(s): ELISA: suitableflow cytometry: suitableimmunoblotting: suitableimmunohistochemistry: 5-10 μg/mL using pronase-retrieved formalin-fixed, paraffin-embedded human tonsil sections
isotype: IgG1
biological source:
mouse
Quality Level:
200
antibody form:
purified from hybridoma cell culture
antibody product type:
primary antibodies
clone:
BC-24, monoclonal
form:
buffered aqueous solution
species reactivity:
human
concentration:
~1.0 mg/mL
technique(s):
ELISA: suitableflow cytometry: suitableimmunoblotting: suitableimmunohistochemistry: 5-10 μg/mL using pronase-retrieved formalin-fixed, paraffin-embedded human tonsil sections
isotype:
IgG1
biological source: mouse
Quality Level: 200
antibody form: purified from hybridoma cell culture
antibody product type: primary antibodies
clone: 13C4, monoclonal
form: buffered aqueous solution
species reactivity: E. coli
concentration: __
technique(s): __
isotype: __
biological source:
mouse
Quality Level:
200
antibody form:
purified from hybridoma cell culture
antibody product type:
primary antibodies
clone:
13C4, monoclonal
form:
buffered aqueous solution
species reactivity:
E. coli
concentration:
__
technique(s):
__
isotype:
__
biological source: mouse
Quality Level: __
antibody form: purified from hybridoma cell culture
antibody product type: primary antibodies
clone: COL-10, monoclonal
form: buffered aqueous solution
species reactivity: deer, porcine, human
concentration: ~1 mg/mL
technique(s): immunoblotting: suitableimmunofluorescence: 5-10 μg/mL using human osteosarcoma SaOS-2 cellsimmunohistochemistry: suitable
isotype: __
biological source:
mouse
Quality Level:
__
antibody form:
purified from hybridoma cell culture
antibody product type:
primary antibodies
clone:
COL-10, monoclonal
form:
buffered aqueous solution
species reactivity:
deer, porcine, human
concentration:
~1 mg/mL
technique(s):
immunoblotting: suitableimmunofluorescence: 5-10 μg/mL using human osteosarcoma SaOS-2 cellsimmunohistochemistry: suitable
isotype:
__
biological source: mouse
Quality Level: __
antibody form: purified from hybridoma cell culture
antibody product type: primary antibodies
clone: GT-34, monoclonal
form: buffered aqueous solution
species reactivity: goat, sheep
concentration: ~1 mg/mL
technique(s): indirect ELISA: 0.25-0.5 μg/mL using 5μg/ml Goat IgG for coating.
isotype: IgG1
biological source:
mouse
Quality Level:
__
antibody form:
purified from hybridoma cell culture
antibody product type:
primary antibodies
clone:
GT-34, monoclonal
form:
buffered aqueous solution
species reactivity:
goat, sheep
concentration:
~1 mg/mL
technique(s):
indirect ELISA: 0.25-0.5 μg/mL using 5μg/ml Goat IgG for coating.
isotype:
IgG1