Monoclonal Anti-TCR beta antibody produced in mouse

Description

• General description: The antibody MEM-262 recognizes β chains of the TCR expressed by HPB-ALL cell line [carrying V(beta5.3)] and a small subset of peripheral blood T cells.TCR β/TCRB (T cell receptor β chain) is located on human chromosome 7q34. This gene has at least 65 rearrangeable Vβ gene segments (27 Vβ families), two Dβ segments (Dβ1 and Dβ2), two clusters of Jβ gene segments (Jβ1.1–Jβ 1.6 and Jβ2.1–Jβ2.7) and two Cβ gene segments.
• Immunogen: Human thymoma cell line HPB-ALL
• Application: The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 2-8 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
• Biochem/physiol Actions: The complementary determining region 3 (CDR3) of the TCR β/TCRB (T cell receptor β) is essential for the identification of the major histocompatibility complex (MHC)−peptide complex.
• Features and Benefits: Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
• Physical form: Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
• Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.