SML0652
IOX2
≥98% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 931398-72-0
Synonym(S): JICL38, N-[[1,2-Dihydro-4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]carbonyl]-glycine, N-[[4-Hydroxy-2-oxo-1-(phenylmethyl)-1,2-dihydro-3-quinolinyl]carbonyl]glycine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | SML0652-5-MG | In Stock | ₹ 9,883.23 |
| 25 MG | SML0652-25-MG | In Stock | ₹ 44,945.40 |
SML0652 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 9,883.23
GST (18%): ₹ 1,778.981
Total Price: ₹ 11,662.211
Quality Level
100
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
OC(C1=C(N2CC3=CC=CC=C3)C=CC=C1)=C(C(NCC(O)=O)=O)C2=O
InChI
1S/C19H16N2O5/c22-15(23)10-20-18(25)16-17(24)13-8-4-5-9-14(13)21(19(16)26)11-12-6-2-1-3-7-12/h1-9,24H,10-11H2,(H,20,25)(H,22,23)
InChI key
CAOSCCRYLYQBES-UHFFFAOYSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Selleck Chemical LLC IOX2 10mM/1mL 931398-72-0 JICL38 | Selleck Chemical LLC | ₹ 19,507.68 | |
 | Sigma Aldrich Fine Chemicals Biosciences IOX2 >=98% (HPLC) | 931398-72-0 | MFCD22580424 | 25MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 50,822.64 | |
| | Sigma Aldrich Fine Chemicals Biosciences IOX2 >=98% (HPLC) | 931398-72-0 | MFCD22580424 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 12,786.94 | |
 | 931398-72-0 | Iox2 | A2B Chem | ₹ 4,791.36 - ₹ 23,272.32 |
Related Products
Description
- Application: IOX2 has been used as PHD inhibitor to induce pseudo-hypoxia.[1]
- Biochem/physiol Actions: IOX2 is selective and potent inhibitor of prolyl hydroxylases (PHD). Stabilization of HIF-1R through inhibition of PHD has been examined as a potential treatment for ischemic diseases including anemia, myocardial infarction, and stroke. IOX2 is a selective inhibitor of the hypoxia inducible factor (HIF) prolyl-hydroxylases (PHD) that exhibits up-regulation of HIF1a in zebrafish. For full characterization details, please visit the IOX2 probe summary on the Structural Genomics Consortium (SGC) website.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
- Features and Benefits: IOX2 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
Quality Level: 100
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 5 mg/mL, clear (warmed)
storage temp.: 2-8°C
SMILES string: OC(C1=C(N2CC3=CC=CC=C3)C=CC=C1)=C(C(NCC(O)=O)=O)C2=O
InChI: 1S/C19H16N2O5/c22-15(23)10-20-18(25)16-17(24)13-8-4-5-9-14(13)21(19(16)26)11-12-6-2-1-3-7-12/h1-9,24H,10-11H2,(H,20,25)(H,22,23)
InChI key: CAOSCCRYLYQBES-UHFFFAOYSA-N
Quality Level:
100
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 5 mg/mL, clear (warmed)
storage temp.:
2-8°C
SMILES string:
OC(C1=C(N2CC3=CC=CC=C3)C=CC=C1)=C(C(NCC(O)=O)=O)C2=O
InChI:
1S/C19H16N2O5/c22-15(23)10-20-18(25)16-17(24)13-8-4-5-9-14(13)21(19(16)26)11-12-6-2-1-3-7-12/h1-9,24H,10-11H2,(H,20,25)(H,22,23)
InChI key:
CAOSCCRYLYQBES-UHFFFAOYSA-N
Quality Level: 100
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 20 mg/mL, clear
storage temp.: 2-8°C
SMILES string: O=C(OCC)CCNC1=CC(N2CCC(C=CC=C3)=C3CC2)=NC(C4=CC=CC=N4)=N1
InChI: 1S/C24H27N5O2/c1-2-31-23(30)10-14-26-21-17-22(28-24(27-21)20-9-5-6-13-25-20)29-15-11-18-7-3-4-8-19(18)12-16-29/h3-9,13,17H,2,10-12,14-16H2,1H3,(H,26,27,28)
InChI key: WBKCKEHGXNWYMO-UHFFFAOYSA-N
Quality Level:
100
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 20 mg/mL, clear
storage temp.:
2-8°C
SMILES string:
O=C(OCC)CCNC1=CC(N2CCC(C=CC=C3)=C3CC2)=NC(C4=CC=CC=N4)=N1
InChI:
1S/C24H27N5O2/c1-2-31-23(30)10-14-26-21-17-22(28-24(27-21)20-9-5-6-13-25-20)29-15-11-18-7-3-4-8-19(18)12-16-29/h3-9,13,17H,2,10-12,14-16H2,1H3,(H,26,27,28)
InChI key:
WBKCKEHGXNWYMO-UHFFFAOYSA-N
Quality Level: 100
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 15 mg/mL, clear
storage temp.: 2-8°C
SMILES string: OC(CCNC1=CC(N2CCC(C=CC=C3)=C3CC2)=NC(C4=CC=CC=N4)=N1)=O
InChI: 1S/C22H23N5O2/c28-21(29)8-12-24-19-15-20(26-22(25-19)18-7-3-4-11-23-18)27-13-9-16-5-1-2-6-17(16)10-14-27/h1-7,11,15H,8-10,12-14H2,(H,28,29)(H,24,25,26)
InChI key: AVZCPICCWKMZDT-UHFFFAOYSA-N
Quality Level:
100
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 15 mg/mL, clear
storage temp.:
2-8°C
SMILES string:
OC(CCNC1=CC(N2CCC(C=CC=C3)=C3CC2)=NC(C4=CC=CC=N4)=N1)=O
InChI:
1S/C22H23N5O2/c28-21(29)8-12-24-19-15-20(26-22(25-19)18-7-3-4-11-23-18)27-13-9-16-5-1-2-6-17(16)10-14-27/h1-7,11,15H,8-10,12-14H2,(H,28,29)(H,24,25,26)
InChI key:
AVZCPICCWKMZDT-UHFFFAOYSA-N
Quality Level: 100
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 15 mg/mL, clear
storage temp.: 2-8°C
SMILES string: CC(C)N1CCN(C2=NC=C(C3=CC4=C(C=NN4C(C)C)C(C(NCC5=C(CCC)C=C(C)NC5=O)=O)=C3)C=C2)CC1
InChI: 1S/C33H43N7O2/c1-7-8-24-15-23(6)37-33(42)28(24)19-35-32(41)27-16-26(17-30-29(27)20-36-40(30)22(4)5)25-9-10-31(34-18-25)39-13-11-38(12-14-39)21(2)3/h9-10,15-18,20-22H,7-8,11-14,19H2,1-6H3,(H,35,41)(H,37,42)
InChI key: DPJNKUOXBZSZAI-UHFFFAOYSA-N
Quality Level:
100
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 15 mg/mL, clear
storage temp.:
2-8°C
SMILES string:
CC(C)N1CCN(C2=NC=C(C3=CC4=C(C=NN4C(C)C)C(C(NCC5=C(CCC)C=C(C)NC5=O)=O)=C3)C=C2)CC1
InChI:
1S/C33H43N7O2/c1-7-8-24-15-23(6)37-33(42)28(24)19-35-32(41)27-16-26(17-30-29(27)20-36-40(30)22(4)5)25-9-10-31(34-18-25)39-13-11-38(12-14-39)21(2)3/h9-10,15-18,20-22H,7-8,11-14,19H2,1-6H3,(H,35,41)(H,37,42)
InChI key:
DPJNKUOXBZSZAI-UHFFFAOYSA-N