SML1410
A-366
≥98% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 1527503-11-2
Synonym(S): 5′-Methoxy-6′-[3-(1-pyrrolidinyl)propoxy]-spiro[cyclobutane-1,3′-[3H]indol]-2′-amine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | SML1410-5-MG | In Stock | ₹ 13,293.10 |
| 25 MG | SML1410-25-MG | In Stock | ₹ 41,849.45 |
SML1410 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 13,293.10
GST (18%): ₹ 2,392.758
Total Price: ₹ 15,685.858
Quality Level
100
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 10 mg/mL, clear
storage temp.
2-8°C
SMILES string
NC1=NC2=CC(OCCCN3CCCC3)=C(OC)C=C2C14CCC4
InChI
1S/C19H27N3O2/c1-23-16-12-14-15(21-18(20)19(14)6-4-7-19)13-17(16)24-11-5-10-22-8-2-3-9-22/h12-13H,2-11H2,1H3,(H2,20,21)
InChI key
BKCDJTRMYWSXMC-UHFFFAOYSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences A-366 >=98% (HPLC) | 1527503-11-2 | MFCD28133403 | 25MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 47,434.46 | |
| | Sigma Aldrich Fine Chemicals Biosciences A-366 >=98% (HPLC) | 1527503-11-2 | MFCD28133403 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 12,367.70 | |
 | Medchemexpress LLC HY-12583 10mg , A-366 CAS:1527503-11-2 Purity:>98% | Medchemexpress LLC | ₹ 13,026.51 | |
 | 5'-Methoxy-6'-[3-(1-pyrrolidinyl)propoxy]spiro[cyclobutane-1,3'-[3H]indol]-2'-amine | Aaron Chemicals LLC | ₹ 1,882.32 - ₹ 16,855.32 |
Related Products
Description
- Biochem/physiol Actions: A-366 is an SGC chemical probe for G9a/GLP, developed in collaboration with Abbvie. A-366 is a potent, selective inhibitor of the histone methyltransferase G9a. The IC50 values for G9a inhbition in enzymatic and cell based assays are 3.3 and approximately 3 μM, respectively. A-366 has little or no detectable activity against a panel of 21 other methyltransferases. For full characterization details, please visit the A-366 probe summary on the Structural Genomics Consortium (SGC) website.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
- Features and Benefits: A-366 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.
- Other Notes: A-366 has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the A-366 probe summary on the Chemical Probes Portal website.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Acute 1
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
Quality Level: 100
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 10 mg/mL, clear
storage temp.: 2-8°C
SMILES string: NC1=NC2=CC(OCCCN3CCCC3)=C(OC)C=C2C14CCC4
InChI: 1S/C19H27N3O2/c1-23-16-12-14-15(21-18(20)19(14)6-4-7-19)13-17(16)24-11-5-10-22-8-2-3-9-22/h12-13H,2-11H2,1H3,(H2,20,21)
InChI key: BKCDJTRMYWSXMC-UHFFFAOYSA-N
Quality Level:
100
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 10 mg/mL, clear
storage temp.:
2-8°C
SMILES string:
NC1=NC2=CC(OCCCN3CCCC3)=C(OC)C=C2C14CCC4
InChI:
1S/C19H27N3O2/c1-23-16-12-14-15(21-18(20)19(14)6-4-7-19)13-17(16)24-11-5-10-22-8-2-3-9-22/h12-13H,2-11H2,1H3,(H2,20,21)
InChI key:
BKCDJTRMYWSXMC-UHFFFAOYSA-N
Quality Level: 100
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 20 mg/mL, clear
storage temp.: 2-8°C
SMILES string: O=S(NC1=CC=C(N(C)C(C(C)=C2)=O)C2=C1)(C3=C(OC)C=C(C#N)C=C3)=O
InChI: 1S/C19H17N3O4S/c1-12-8-14-10-15(5-6-16(14)22(2)19(12)23)21-27(24,25)18-7-4-13(11-20)9-17(18)26-3/h4-10,21H,1-3H3
InChI key: UEMQPCYDWCSVCU-UHFFFAOYSA-N
Quality Level:
100
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 20 mg/mL, clear
storage temp.:
2-8°C
SMILES string:
O=S(NC1=CC=C(N(C)C(C(C)=C2)=O)C2=C1)(C3=C(OC)C=C(C#N)C=C3)=O
InChI:
1S/C19H17N3O4S/c1-12-8-14-10-15(5-6-16(14)22(2)19(12)23)21-27(24,25)18-7-4-13(11-20)9-17(18)26-3/h4-10,21H,1-3H3
InChI key:
UEMQPCYDWCSVCU-UHFFFAOYSA-N
Quality Level: 100
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 20 mg/mL, clear
storage temp.: 2-8°C
SMILES string: O=C(OC(C)(C)C)C[C@H]1C2=NN=C(C)N2C(SC(C)=C3C)=C3C(C4=CC=C(Cl)C=C4)=N1
InChI: 1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1
InChI key: DNVXATUJJDPFDM-KRWDZBQOSA-N
Quality Level:
100
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 20 mg/mL, clear
storage temp.:
2-8°C
SMILES string:
O=C(OC(C)(C)C)C[C@H]1C2=NN=C(C)N2C(SC(C)=C3C)=C3C(C4=CC=C(Cl)C=C4)=N1
InChI:
1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1
InChI key:
DNVXATUJJDPFDM-KRWDZBQOSA-N
Quality Level: 100
Assay: ≥95% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 20 mg/mL, clear
storage temp.: 2-8°C
SMILES string: O=C(OC(C)(C)C)C[C@@H]1C2=NN=C(C)N2C(SC(C)=C3C)=C3C(C4=CC=C(Cl)C=C4)=N1
InChI: 1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m1/s1
InChI key: DNVXATUJJDPFDM-QGZVFWFLSA-N
Quality Level:
100
Assay:
≥95% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 20 mg/mL, clear
storage temp.:
2-8°C
SMILES string:
O=C(OC(C)(C)C)C[C@@H]1C2=NN=C(C)N2C(SC(C)=C3C)=C3C(C4=CC=C(Cl)C=C4)=N1
InChI:
1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m1/s1
InChI key:
DNVXATUJJDPFDM-QGZVFWFLSA-N