SML2340
SGC8158
≥98% (HPLC)
Manufacturer: Sigma Aldrich
Synonym(S): 5′-S-[4-[(4′-Chlorobiphenyl-3-ylmethyl)amino]butyl]-5′-thioadenosine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | SML2340-5-MG | In Stock | ₹ 19,409.23 |
| 25 MG | SML2340-25-MG | In Stock | ₹ 62,655.10 |
SML2340 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 19,409.23
GST (18%): ₹ 3,493.661
Total Price: ₹ 22,902.891
Quality Level
100
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
ClC(C=C1)=CC=C1C2=CC(CNCCCCSC[C@H]3O[C@@H](N(C=N4)C5=C4C(N)=NC=N5)[C@H](O)[C@@H]3O)=CC=C2
Related Products
Description
- Biochem/physiol Actions: SGC8158 isthe active component produced by cell reductases from the prodrug, SGC3027, a selective and cell-active inhibitor of protein arginine N-methyltransferase (PRMT7). SGC8158 was shown to inhibit PRMT7 with an IC50 value < 2.5 nM for methylation of H2B (23-37) and greater than 40-fold selectivity over other histone methyltransferases and non-epigenetic targets. SGC3027 inhibited the methylation of HSP70 In cellular assays using C2C12 cells with an IC50 value of 1.3 microM. The closely related SGC3027N is significantly less active in the cellular assay, and is a control compound for cellular studies.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
Quality Level: 100
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 2 mg/mL, clear
storage temp.: 2-8°C
SMILES string: ClC(C=C1)=CC=C1C2=CC(CNCCCCSC[C@H]3O[C@@H](N(C=N4)C5=C4C(N)=NC=N5)[C@H](O)[C@@H]3O)=CC=C2
Quality Level:
100
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 2 mg/mL, clear
storage temp.:
2-8°C
SMILES string:
ClC(C=C1)=CC=C1C2=CC(CNCCCCSC[C@H]3O[C@@H](N(C=N4)C5=C4C(N)=NC=N5)[C@H](O)[C@@H]3O)=CC=C2
Quality Level: __
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 2 mg/mL, clear
storage temp.: 2-8°C
SMILES string: ClC(C=C1)=CC=C1C2=CC(CN(C(CC(C)(C)C(C(C(C)=C3C)=O)=C(C)C3=O)=O)CCCCSC[C@H]4O[C@@H](N(C=N5)C6=C5C(N)=NC=N6)[C@H]7[C@@H]4OC(C)(C)O7)=CC=C2
Quality Level:
__
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 2 mg/mL, clear
storage temp.:
2-8°C
SMILES string:
ClC(C=C1)=CC=C1C2=CC(CN(C(CC(C)(C)C(C(C(C)=C3C)=O)=C(C)C3=O)=O)CCCCSC[C@H]4O[C@@H](N(C=N5)C6=C5C(N)=NC=N6)[C@H]7[C@@H]4OC(C)(C)O7)=CC=C2
Quality Level: __
Assay: __
form: powder
color: white to beige
solubility: DMSO: 2 mg/mL, clear
storage temp.: −20°C
SMILES string: ClC(C=C1)=CC=C1C2=CC(CN(C(CC(C)(C)C(C(C(C)=C3C)=O)=C(C)C3=O)=O)CCCCSC[C@H]4O[C@@H](N(C=N5)C6=C5C(N)=NC=N6)[C@H](O)[C@@H]4O)=CC=C2
Quality Level:
__
Assay:
__
form:
powder
color:
white to beige
solubility:
DMSO: 2 mg/mL, clear
storage temp.:
−20°C
SMILES string:
ClC(C=C1)=CC=C1C2=CC(CN(C(CC(C)(C)C(C(C(C)=C3C)=O)=C(C)C3=O)=O)CCCCSC[C@H]4O[C@@H](N(C=N5)C6=C5C(N)=NC=N6)[C@H](O)[C@@H]4O)=CC=C2
Quality Level: __
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 2 mg/mL, clear
storage temp.: −20°C
SMILES string: O=C(N1C)N(C)C2=C1C=C(OC3=CC=CC(OCCC)=C3)C(NS(C4=CC(C(NCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N5C[C@H](O)C[C@H]5C(NCC6=CC=C(C7=C(C)N=CS7)C=C6)=O)=O)=O)=O)=CC=C4)(=O)=O)=C2
Quality Level:
__
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 2 mg/mL, clear
storage temp.:
−20°C
SMILES string:
O=C(N1C)N(C)C2=C1C=C(OC3=CC=CC(OCCC)=C3)C(NS(C4=CC(C(NCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N5C[C@H](O)C[C@H]5C(NCC6=CC=C(C7=C(C)N=CS7)C=C6)=O)=O)=O)=O)=CC=C4)(=O)=O)=C2