RAB0362

Human MMP-1 ELISA Kit

for cell and tissue lysates

Manufacturer: Sigma Aldrich

Synonym(S): MMP-1, Matrix metalloproteinase-1

Select a Size

Pack Size SKU Availability Price
1 KIT RAB0362-1-KIT In Stock ₹ 64,524.30

RAB0362 - 1 KIT

₹ 64,524.30

In Stock

Quantity

1

Base Price: ₹ 64,524.30

GST (18%): ₹ 11,614.374

Total Price: ₹ 76,138.674

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitablecapture ELISA: suitable

input

sample type tissue lysatesample type cell lysate

assay range

inter-assay cv: <12%intra-assay cv: <10%sensitivity: 8 pg/mLstandard curve range: 24.69-18000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... MMP1(4312)

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Description

  • General description: The Human MMP-1 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human MMP-1 cell lysate and tissue lysate.
  • Immunogen: Recombinant Human MMP1
  • Application: For research use only. Not for use in diagnostic procedures.Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
  • Biochem/physiol Actions: Matrix metalloproteinases (MMPs) enzymes play a central role in the maintenance and remodeling of the extracellular matrix.[1] Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular diseases, skeletal growth-plate disorders, and cancer metastasis.[2][3][4][5] MMP-1 is a secreted collagenase with specificity toward Type I, II, III, VII, and X collagens, aggrecan, serpins, and α2-macroglobulin.[6][7] It is overexpressed in lumbar intervertebral disc degeneration (IDD).[8] It might also be associated with rheumatoid arthritis and osteoarthritis.[6][9] MMP-1 is linked with juvenile idiopathic arthritis. Genetic variations in MMP-1 can affect the susceptibility and severity of this disease.[10] MMP-1 might facilitate fibrous plaque disruption via degradation of interstitial collagens and thinning of the fibrous cap.[11]
  • Other Notes: A sample Certificate of Analysis is available for this product.Please type the word sample in the text box provided for lot number.

SAFETY INFORMATION

Pictograms

GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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RAB0362

for cell and tissue lysates...


species reactivity:
human

packaging:
kit of 96 wells (12 strips x 8 wells)

technique(s):
ELISA: suitablecapture ELISA: suitable

input:
sample type tissue lysatesample type cell lysate

assay range:
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 8 pg/mLstandard curve range: 24.69-18000 pg/mL

detection method:
colorimetric

shipped in:
wet ice

storage temp.:
−20°C

Gene Information:
human ... MMP1(4312)

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human

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kit of 96 wells (12 strips x 8 wells)

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input:
sample type urinesample type cell culture supernatant(s)sample type serumsample type plasma

assay range:
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 3 pg/mLstandard curve range: 2.06-1500 pg/mL

detection method:
colorimetric

shipped in:
wet ice

storage temp.:
−20°C

Gene Information:
human ... MMP10(4319)

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Gene Information:
human ... MMP13(4322)

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input:
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assay range:
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 3,500 pg/mLstandard curve range: 3.3-800 ng/mL

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colorimetric

shipped in:
wet ice

storage temp.:
−20°C

Gene Information:
human ... MMP2(4313)