RAB0490

Human soluble TNF Receptor 2 ELISA Kit

for serum, plasma for serum, plasma, cell culture supernatant and urine

Manufacturer: Sigma Aldrich

Synonym(S): sTNFRII

Select a Size

Pack Size SKU Availability Price
1 KIT RAB0490-1-KIT In Stock ₹ 64,524.30

RAB0490 - 1 KIT

₹ 64,524.30

In Stock

Quantity

1

Base Price: ₹ 64,524.30

GST (18%): ₹ 11,614.374

Total Price: ₹ 76,138.674

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitablecapture ELISA: suitable

input

sample type plasmasample type cell culture supernatant(s)sample type plasmasample type serumsample type urinesample type serum

assay range

inter-assay cv: <12%intra-assay cv: <10%sensitivity: 5 pg/mLstandard curve range: 2.74-2000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

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Description

  • General description: The Human sTNF RII ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human sTNF RII in serum, plasma, cell culture supernatants and urine.
  • Immunogen: Recombinant Human TNF RII
  • Application: For research use only. Not for use in diagnostic procedures.Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
  • Biochem/physiol Actions: Tumor necrosis factor receptor 2 (TNFR2) plays a vital role in inducing signals for various cellular process, including proliferation of thymocytes and peripheral T cells, T cell secretion of granulocyte-macrophage colony-stimulating factor, inhibition of early hematopoiesis, and the inactivation and clearance of TNF by the kidney. Mutation in the gene leads to hematopoietic cell malignancies, neuroblastoma, glioma, cervical and ovarian carcinoma.[1] TRAF2 interacts with TNFR2 and activates NF-kappa B (NF-κB) pathway.[2] TNFR2, which lacks death domains, modulates the effect of other death receptor TNFR1, which induces T cell death.[3][1] TNFR2 plays an essential role in TNF-α–induced leukocyte-endothelial interaction. TNFR2 is considered as a potential therapeutic alternative, as it has capacity to nullify the common side effects associated with drugs targeting TNF-α or p55.[4]
  • Other Notes: A sample Certificate of Analysis is available for this product.Please type the word sample in the text box provided for lot number.

SAFETY INFORMATION

Pictograms

GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

WGK

WGK 3

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species reactivity:
human

packaging:
kit of 96 wells (12 strips x 8 wells)

technique(s):
ELISA: suitablecapture ELISA: suitable

input:
sample type plasmasample type cell culture supernatant(s)sample type plasmasample type serumsample type urinesample type serum

assay range:
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 5 pg/mLstandard curve range: 2.74-2000 pg/mL

detection method:
colorimetric

shipped in:
wet ice

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−20°C

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