420200
JC-1
A cationic, fluorescent, carbocyanine dye that can be used as a ratiometric indicator of mitochondrial potential δΨm in cells, tissues, and isolated mitochondria.
Manufacturer: Sigma Aldrich
CAS Number: 47729-63-5
Synonym(S): JC-1, 5,5ʹ,6,6ʹ-Tetrachloro-1,1ʹ,3,3ʹ-tetraethylbenzimidazolylcarbocyanine Iodide
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | 420200-5-MG | In Stock | ₹ 45,620.00 |
420200 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 45,620.00
GST (18%): ₹ 8,211.60
Total Price: ₹ 53,831.60
Quality Level
100
Assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freezeprotect from light
color
red-orange
solubility
DMSO: 5 mg/mL
shipped in
ambient
storage temp.
−20°C
InChI
1S/C25H27Cl4N4.HI/c1-5-30-20-12-16(26)17(27)13-21(20)31(6-2)24(30)10-9-11-25-32(7-3)22-14-18(28)19(29)15-23(22)33(25)8-4;/h9-15H,5-8H2,1-4H3;1H/q+1;/p-1
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Enzo Life Sciences JC-1 (ultra pure) (5mg). CAS: 47729-63-5 | Enzo Life Sciences | ₹ 24,696.89 | |
| | Enzo Life Sciences JC-1 . iodide (5mg). CAS: 47729-63-5 | Enzo Life Sciences | ₹ 31,092.50 |
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Description
- General description: A cationic, fluorescent, carbocyanine dye that can be used as a ratiometric indicator of mitochondrial potential ΔΨm in cells, tissues, and isolated mitochondria. It labels mitochondria with high membrane potential orange and mitochondria with low membrane potential green. Mitochondrial depolarization is indicated by a decrease in the red/green fluorescence intensity ratio. Ideal for detection of collapse of ΔΨm induced by uncouplers of mitochondrial respiration. The potential-sensitive color shift is due to concentration-dependent formation of red fluorescent J-aggregates. JC-1 has also been used in a functional assay of multidrug-resistance cells and in apoptosis-related mitochondrial modifications.
- Biochem/physiol Actions: Cell permeable: no
- Packaging: Packaged under inert gas
- Warning: Toxicity: Irritant (B)
- Reconstitution: Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Do not reuse thawed samples.
- Other Notes: Mathur, A., et al. 2000. Cardiovasc. Res. 46, 126.Gravance, C.G., et al. 2000. Theriogenology53, 1691.Chanda, B., and Mathew, M.K. 1999. Biochim Biophys. Acta 1416, 92.Dedov, V.N., and Roufogalis, B.D. 1999. FEBS Lett. 456, 171.Polla, B.S., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 6458.White, R.J., and Reynolds, I.J. 1996. J. Neurosci. 16, 5688.Ankacrona, M., et al. 1995. Neuron 15, 961.Reers, M., et al. 1995. Methods Enzymol. 260, 406.Cossarizza, A., et al. 1993. Biochem. Biophys. Res. Commun. 197, 40.
- Legal Information: CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
Quality Level: 100
Assay: ≥95% (HPLC)
form: solid
manufacturer/tradename: Calbiochem®
storage condition: OK to freezeprotect from light
color: red-orange
solubility: DMSO: 5 mg/mL
shipped in: ambient
storage temp.: −20°C
InChI: 1S/C25H27Cl4N4.HI/c1-5-30-20-12-16(26)17(27)13-21(20)31(6-2)24(30)10-9-11-25-32(7-3)22-14-18(28)19(29)15-23(22)33(25)8-4;/h9-15H,5-8H2,1-4H3;1H/q+1;/p-1
Quality Level:
100
Assay:
≥95% (HPLC)
form:
solid
manufacturer/tradename:
Calbiochem®
storage condition:
OK to freezeprotect from light
color:
red-orange
solubility:
DMSO: 5 mg/mL
shipped in:
ambient
storage temp.:
−20°C
InChI:
1S/C25H27Cl4N4.HI/c1-5-30-20-12-16(26)17(27)13-21(20)31(6-2)24(30)10-9-11-25-32(7-3)22-14-18(28)19(29)15-23(22)33(25)8-4;/h9-15H,5-8H2,1-4H3;1H/q+1;/p-1
Quality Level: 100
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InChI: 1S/C10H13.ClH.Mg/c1-10(2,3)9-7-5-4-6-8-9;;/h4-8H,1H2,2-3H3;1H;/q;;+1/p-1
Quality Level:
100
Assay:
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form:
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manufacturer/tradename:
__
storage condition:
__
color:
__
solubility:
__
shipped in:
__
storage temp.:
__
InChI:
1S/C10H13.ClH.Mg/c1-10(2,3)9-7-5-4-6-8-9;;/h4-8H,1H2,2-3H3;1H;/q;;+1/p-1
Quality Level: 100
Assay: 97%
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InChI: 1S/C34H72N.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35(3,4)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2;/h5-34H2,1-4H3;1H/q+1;/p-1
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storage condition:
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storage temp.:
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InChI:
1S/C34H72N.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35(3,4)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2;/h5-34H2,1-4H3;1H/q+1;/p-1
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Assay: 97%
form: solid
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color: __
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InChI: 1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m1/s1
Quality Level:
200
Assay:
97%
form:
solid
manufacturer/tradename:
__
storage condition:
__
color:
__
solubility:
__
shipped in:
__
storage temp.:
__
InChI:
1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m1/s1