Description

• General description: Calorimetry studies show that the two lectin-like domains flanking the central catalytic domain of Neuraminidase serve as the recognition and binding sites for sialic acid-containing substrates. [1]
• Application: Neuraminidase from Vibrio cholera has been used in a study to describe a five-step purification method. [2] It has also been used in a study to investigate modification of leukemia L1210 tumor cells. [3]
• Quality: Preservative free.
• Unit Definition: One unit will liberate 1.0 μmole of N-acetylneuraminic acid per min at pH 5.0 at 37 °C using NAN-lactose or bovine submaxillary mucin, unless otherwise specified. Prices based on units using NAN-lactose as substrate.
• Physical form: Solution in 50 mM sodium acetate, pH 5.5, containing 0.15 M sodium chloride and 4 mM calcium chloride, 0.2 μm filtered..
• Preparation Note: A further purification by affinity chromatography of our Type III.