Invitrogen™mirVana™ miRNA Inhibitor, Negative Control #1

Description

• miRNA inhibitors are small, chemically modified single-stranded RNA molecules designed to specifically bind to and inhibit endogenous miRNA molecules and enable miRNA functional analysis by down-regulation of miRNA activity
• We have now released the second generation of miRNA inhibitors, mir Vana™ miRNA Inhibitors, which: Display better potency than lead competitor's product Offer maximum and consistent effect in vitro at low miRNA inhibitor concentration Target the most updated Sanger content Can be used in vitro and in vivo , offering consistency throughout your entire research project Are non-toxic Positive and negative controls are also available for use along with mir Vana™ miRNA Inhibitors in miRNA down-regulation experiments
• mir Vana™ miRNA Inhibitor Negative Control #1 mir Vana™ miRNA Inhibitor Negative Control #1 is intended for use as a negative control for experiments using mir Vana™ miRNA Inhibitors
• Transfect this negative control using the same methodology as for your positive control (such as let-7c Positive Control) and experimental mir Vana™ miRNA Inhibitors
• Use target expression from negative control-transfected samples as a baseline for evaluation of the effect of the control and experimental miRNA inhibitor on target gene expression
• First Generation Inhibitor Controls Our first-generation miRNA inhibitors (and controls), Ambion™ Anti-miR™ miRNA Inhibitors, have lower specificity and potency, plus a lower strand specificity compared to the new mir Vana™ miRNA Inhibitors
• These first-generation inhibitors are recommended for completing ongoing in vitro miRNA studies
• For new studies or in vivo studies, we highly recommend our new mir Vana™ miRNA Inhibitors and their corresponding controls.