01-670-538

ATG5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-670-538-Each-of-1 In Stock ₹ 45,988.50

01-670-538 - Each of 1

₹ 45,988.50

In Stock

Quantity

1

Base Price: ₹ 45,988.50

GST (18%): ₹ 8,277.93

Total Price: ₹ 54,266.43

Antigen

ATG5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Atg5

Gene Alias

2010107M05Rik; 3110067M24Rik; APG 5; APG5; APG5 autophagy 5 like (APG5L); APG5 autophagy 5-like protein; APG5 autophagy 5-like protein, isoform 1; APG5L; APG5-LIKE; apoptosis-specific protein; Apoptosis-specific protein (ASP); ASP; atg5; Atg-5; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); atg5.L; Atg5l; Atg5-PA; autophagy 5-like protein; autophagy protein 5; autophagy related 5; autophagy related 5 L homeolog; autophagy related 5-like protein; Autophagy-related 5; autophagy-specific gene 5; AW319544; C88337; CG1643; CG1643-PA; DmAtg5; Dmel\CG1643; Dmel_CG1643; hAPG5; hypothetical protein LOC532686; LD34980p; Paddy; XELAEV_18027227mg; zgc:100934

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

9474

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Form

Lyophilized

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

antibody with no preservative

Gene Accession No.

Q9H1Y0

Gene Symbols

Atg5

Immunogen

Synthetic peptide corresponding to the C-terminal residues of human APG-5L.

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 500 μL of distilled water
  • After reconstitution, store aliquots at -20oC for a higher stability, and at 4oC with an appropriate antibacterial agent
  • ATG5 (Autophagy Related 5) is an important element for autophagy and may play an important role in the apoptotic process
  • ATG5 is also involved in other cellular processes that include mitochondrial quality control after oxidative damage, negative regulation of the innate anti-viral immune response, lymphocyte development and proliferation, MHC II antigen presentation, and adipocyte differentiation
  • Following conjugation to ATG12, the conjugate participates in the formation of autophagosome
  • ATG5 contributes to autophagic cell death by interacting with Fas-associated protein with death domain (FADD)
  • The ATG5-ATG12 conjugate forms a cup-shaped isolation membrane that then detaches from the membrane immediately before or after autophagosome formation is completed
  • APG5 may play a role in the apoptotic process, possibly within the modified cytoskeleton
  • Further, APG5 expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity
  • The APG5-APG12 conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells
  • Diseases associated with ATG5 dysfunction include spinocerebellar ataxia.

Compare Similar Items

Show Difference

Img

Thermo Scientific

01-670-538

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Antigen:
ATG5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Atg5

Gene Alias:
2010107M05Rik; 3110067M24Rik; APG 5; APG5; APG5 autophagy 5 like (APG5L); APG5 autophagy 5-like protein; APG5 autophagy 5-like protein, isoform 1; APG5L; APG5-LIKE; apoptosis-specific protein; Apoptosis-specific protein (ASP); ASP; atg5; Atg-5; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); atg5.L; Atg5l; Atg5-PA; autophagy 5-like protein; autophagy protein 5; autophagy related 5; autophagy related 5 L homeolog; autophagy related 5-like protein; Autophagy-related 5; autophagy-specific gene 5; AW319544; C88337; CG1643; CG1643-PA; DmAtg5; Dmel\CG1643; Dmel_CG1643; hAPG5; hypothetical protein LOC532686; LD34980p; Paddy; XELAEV_18027227mg; zgc:100934

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
9474

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
antibody with no preservative

Gene Accession No.:
Q9H1Y0

Gene Symbols:
Atg5

Immunogen:
Synthetic peptide corresponding to the C-terminal residues of human APG-5L.

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-670-539

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Antigen:
MAP1LC3C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP1LC3C

Gene Alias:
ATG8J; Autoph; autophagy-related protein LC3 C; Autophagy-related ubiquitin-like modifier LC3 C; LC3C; LC3-like protein 2; MAP1 light chain 3-like protein 2; MAP1 light chain 3-like protein 3; MAP1A/MAP1B LC3 C; MAP1A/MAP1B light chain 3 C; MAP1LC3C; microtubule associated protein 1 light chain 3 gamma; microtubule-associated protein 1 light chain 3 gamma; Microtubule-associated proteins 1A/1B light chain 3C

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
440738

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
Q9BXW4

Gene Symbols:
MAP1LC3C

Immunogen:
Synthetic peptide corresponding to the N-terminal residues of human MAP1LC3 C. The sequence is 100% conserved in in Macaca mulatta (monkey) and canine

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-670-540

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Antigen:
Beclin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BECN1

Gene Alias:
4921513J16Rik; 5430417M23Rik; APG6; Atg6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; beclin 1; beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1 (coiled-coil, myosin-like BCL2 interacting protein); beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); beclin 1, autophagy related; beclin1; beclin-1; Beclin-1; beclin-1; Beclin-1-C 35 kDa; Beclin-1-C 37 kDa; becn1; Coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; GT197; hypothetical protein MGC73097; myosin-like BCL2 interacting protein; Protein GT197; testis secretory sperm-binding protein Li 215e; VPS30; zgc:73097

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
8678

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Frozen)

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
Q14457

Gene Symbols:
BECN1

Immunogen:
Synthetic peptide corresponding to the C-terminal residues of human Beclin-1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

01-670-542

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Antigen:
GABARAP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GABARAP

Gene Alias:
ATG8A; FLC3B; FLJ25768; GABA type A receptor-associated protein; GABA(A) receptor-associated protein; GABA-A receptor-associated protein; Gabarap; GABARAP a; GABARAP-a; gamma-aminobutyric acid receptor associated protein; gamma-aminobutyric acid receptor-associated protein; gamma-aminobutyric acid reseptor associated protein; HT004; hypothetical protein; MGC120154; MGC120155; MM46

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
11337, 58974

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Frozen), Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
O95166, P60517

Gene Symbols:
GABARAP

Immunogen:
Synthetic peptide corresponding to the N-terminal residues of human GABARAP.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG