01-670-555

Arg3.1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-670-555-Each-of-1 In Stock ₹ 47,015.22

01-670-555 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

Arg3.1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Arc

Gene Alias

activity regulated cytoskeletal-associated protein; activity regulated cytoskeleton associated protein; activity-regulated cytoskeleton-associated protein; Activity-regulated gene 3.1 protein; activity-regulated gene 3.1 protein homolog; Arc; arc {ECO:0000312; ARC/ARG3.1; Arc3.1; arg3.1; Arg3.1/ARC; C86064; Growth factor ARC; hArc; KIAA0278; mArc; rg3.1; RGD:62037}

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

11838, 23237, 54323

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Form

Lyophilized

Applications

Immunohistochemistry (Frozen)

Concentration

1 mg/mL

Formulation

antibody with no preservative

Gene Accession No.

Q63053, Q7LC44, Q9WV31

Gene Symbols

Arc

Immunogen

Synthetic peptide corresponding to the C-terminal residues of human Arg3.1.

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The immunogenic sequence is homologous with mouse and rat Arg3.1
  • Reconstitute with 500 μL of distilled water
  • After reconstitution keep aliquots at -20o for a higher stability, and at 4oC with an appropriate antibacterial agent
  • Master regulator of synaptic plasticity that self-assembles into virion-like capsids that encapsulate RNAs and mediate intercellular RNA transfer in the nervous system
  • ARC protein is released from neurons in extracellular vesicles that mediate the transfer of ARC mRNA into new target cells, where ARC mRNA can undergo activity-dependent translation
  • ARC capsids are endocytosed and are able to transfer ARC mRNA into the cytoplasm of neurons
  • Acts as a key regulator of synaptic plasticity: required for protein synthesis-dependent forms of long-term potentiation (LTP) and depression (LTD) and for the formation of long-term memory
  • Regulates synaptic plasticity by promoting endocytosis of AMPA receptors (AMPARs) in response to synaptic activity: this endocytic pathway maintains levels of surface AMPARs in response to chronic changes in neuronal activity through synaptic scaling, thereby contributing to neuronal homeostasis
  • Acts as a postsynaptic mediator of activity-dependent synapse elimination in the developing cerebellum by mediating elimination of surplus climbing fiber synapses
  • Accumulates at weaker synapses, probably to prevent their undesired enhancement
  • This suggests that ARC-containing virion-like capsids may be required to eliminate synaptic material
  • Required to transduce experience into long-lasting changes in visual cortex plasticity and for long-term memory
  • Involved in postsynaptic trafficking and processing of amyloid-beta A4 (APP) via interaction with PSEN1
  • In addition to its role in synapses, also involved in the regulation of the immune system: specifically expressed in skin-migratory dendritic cells and regulates fast dendritic cell migration, thereby regulating T-cell activation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

01-670-555

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Antigen:
Arg3.1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Arc

Gene Alias:
activity regulated cytoskeletal-associated protein; activity regulated cytoskeleton associated protein; activity-regulated cytoskeleton-associated protein; Activity-regulated gene 3.1 protein; activity-regulated gene 3.1 protein homolog; Arc; arc {ECO:0000312; ARC/ARG3.1; Arc3.1; arg3.1; Arg3.1/ARC; C86064; Growth factor ARC; hArc; KIAA0278; mArc; rg3.1; RGD:62037}

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11838, 23237, 54323

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Form:
Lyophilized

Applications:
Immunohistochemistry (Frozen)

Concentration:
1 mg/mL

Formulation:
antibody with no preservative

Gene Accession No.:
Q63053, Q7LC44, Q9WV31

Gene Symbols:
Arc

Immunogen:
Synthetic peptide corresponding to the C-terminal residues of human Arg3.1.

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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--


Antigen:
CRP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Crp

Gene Alias:
Aa1249; Ab1-341; Ab2-196; Ac1-114; Ac1262; Ac2-069; acute phase protein; CRP; AI255847; Ba2-693; c reactive; C-reactive preprotein; C-reactive protein; C-reactive protein member of the pentraxin family; C-reactive protein(1-205); C-reactive protein, member of the pentraxin family; C-reactive protein, pentraxin-related; C-reactive protein, petaxin related; CRP; CRP1; CSRP; CYRP; D1S181E; DKFZp686M148; DKFZp686M149; MGC149895; MGC88244; pentraxin 1; PTX1; RP11-419N10.4

Host Species:
Goat

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
1401

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
P02741

Gene Symbols:
Crp

Immunogen:
Recombinant human C-Reactive protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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01-670-558

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Antigen:
Clathrin Heavy Chain

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CLTC

Gene Alias:
3110065L21Rik; CHC; CHC17; CHC22; clathrin heavy chain; clathrin heavy chain 1; Clathrin heavy chain 2; clathrin heavy chain like 1; clathrin heavy chain on chromosome 17; Clathrin heavy chain on chromosome 22; clathrin, heavy chain (Hc); clathrin, heavy chain-like 1; clathrin, heavy polypeptide (Hc); Clathrin, heavy polypeptide D; clathrin, heavy polypeptide-like 1; clathrin, heavy polypeptide-like 2; CLH17; CLH-17; CLH22; CLH-22; Cltc; CLTCL; CLTCL1; CLTCL2; CLTD; Hc; KIAA0034; R74732

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
54241

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
P11442

Gene Symbols:
CLTC

Immunogen:
Synthetic peptide corresponding to residues K(619) A G L L Q R A L E H F T D L Y D I K R(638) of rat clathrin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Img

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01-670-560

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Antigen:
beta-1 Adaptin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ap1b1

Gene Alias:
adapter-related protein complex 1 subunit beta-1; adaptor protein complex AP-1 subunit beta-1; adaptor protein complex AP-1, beta 1 subunit; adaptor related protein complex 1 beta 1 subunit; adaptor-related protein complex 1 beta 1 subunit; adaptor-related protein complex 1 subunit beta-1; adaptor-related protein complex 1, beta 1 subunit; adaptor-related protein complex AP-1 beta 1 subunit; adaptor-related protein complex AP-1, beta 1 subunit; ADTB1; ADTB2; AP-1 complex subunit beta-1; AP105A; AP105B; Ap1b1; AP2B1; b2b1660Clo; BAM22; Beta-1-adaptin; beta1-adaptin; Beta-2-adaptin; Beta-adaptin; beta-adaptin 1; beta-prime adaptin; beta-prime-adaptin; CLAPB1; CLAPB2; Clathrin assembly protein complex 1 beta large chain; golgi adaptor HA1/AP1 adaptin beta subunit; Mutant line 1660; plasma membrane adaptor HA2/AP2 adaptor beta subunit

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
162, 29663

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
P52303, Q10567

Gene Symbols:
Ap1b1

Immunogen:
Synthetic peptide corresponding to the N-terminal residues C-K(11) K G E I F E L K A E L N S D K K E K(29) of human AP-1 complex subunit beta-1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG