01-670-554

Arg3.1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-670-554-Each-of-1 In Stock ₹ 47,528.58

01-670-554 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

Arg3.1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Arc

Gene Alias

activity regulated cytoskeletal-associated protein; activity regulated cytoskeleton associated protein; activity-regulated cytoskeleton-associated protein; Activity-regulated gene 3.1 protein; activity-regulated gene 3.1 protein homolog; Arc; arc {ECO:0000312; ARC/ARG3.1; Arc3.1; arg3.1; Arg3.1/ARC; C86064; Growth factor ARC; hArc; KIAA0278; mArc; rg3.1; RGD:62037}

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Frozen)

Concentration

Conc. Not Determined

Formulation

whole serum with no preservative

Gene Accession No.

Q63053, Q7LC44, Q9WV31

Gene Symbols

Arc

Immunogen

Synthetic peptide corresponding to the C-terminal residues of human Arg3.1.

Regulatory Status

RUO

Gene ID (Entrez)

11838, 23237, 54323

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

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Description

  • PA1-18301 detects Arg3.1 from mouse and rat samples
  • PA1-18301 has been successfully used in immunohistochemistry procedures
  • The PA1-18301 immunogen is a synthetic peptide corresponding to the C-terminal residues of human Arg3.1, conjugated to Blue Carrier Protein
  • The sequence is 100% conserved in mouse and rat
  • After reconstitution keep aliquots at -20oC, avoiding freeze/thaw cycles, or 4oC, with an appropriate antibacterial agent
  • Glycerol (1:1) may be added for an andditional stability
  • Reconstitute with 100 μL of distilled water
  • Master regulator of synaptic plasticity that self-assembles into virion-like capsids that encapsulate RNAs and mediate intercellular RNA transfer in the nervous system
  • ARC protein is released from neurons in extracellular vesicles that mediate the transfer of ARC mRNA into new target cells, where ARC mRNA can undergo activity-dependent translation
  • ARC capsids are endocytosed and are able to transfer ARC mRNA into the cytoplasm of neurons
  • Acts as a key regulator of synaptic plasticity: required for protein synthesis-dependent forms of long-term potentiation (LTP) and depression (LTD) and for the formation of long-term memory
  • Regulates synaptic plasticity by promoting endocytosis of AMPA receptors (AMPARs) in response to synaptic activity: this endocytic pathway maintains levels of surface AMPARs in response to chronic changes in neuronal activity through synaptic scaling, thereby contributing to neuronal homeostasis
  • Acts as a postsynaptic mediator of activity-dependent synapse elimination in the developing cerebellum by mediating elimination of surplus climbing fiber synapses
  • Accumulates at weaker synapses, probably to prevent their undesired enhancement
  • This suggests that ARC-containing virion-like capsids may be required to eliminate synaptic material
  • Required to transduce experience into long-lasting changes in visual cortex plasticity and for long-term memory
  • Involved in postsynaptic trafficking and processing of amyloid-beta A4 (APP) via interaction with PSEN1
  • In addition to its role in synapses, also involved in the regulation of the immune system: specifically expressed in skin-migratory dendritic cells and regulates fast dendritic cell migration, thereby regulating T-cell activation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

01-670-554

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Antigen:
Arg3.1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Arc

Gene Alias:
activity regulated cytoskeletal-associated protein; activity regulated cytoskeleton associated protein; activity-regulated cytoskeleton-associated protein; Activity-regulated gene 3.1 protein; activity-regulated gene 3.1 protein homolog; Arc; arc {ECO:0000312; ARC/ARG3.1; Arc3.1; arg3.1; Arg3.1/ARC; C86064; Growth factor ARC; hArc; KIAA0278; mArc; rg3.1; RGD:62037}

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Frozen)

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
Q63053, Q7LC44, Q9WV31

Gene Symbols:
Arc

Immunogen:
Synthetic peptide corresponding to the C-terminal residues of human Arg3.1.

Regulatory Status:
RUO

Gene ID (Entrez):
11838, 23237, 54323

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Img

Thermo Scientific

01-670-555

--


Antigen:
Arg3.1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Arc

Gene Alias:
activity regulated cytoskeletal-associated protein; activity regulated cytoskeleton associated protein; activity-regulated cytoskeleton-associated protein; Activity-regulated gene 3.1 protein; activity-regulated gene 3.1 protein homolog; Arc; arc {ECO:0000312; ARC/ARG3.1; Arc3.1; arg3.1; Arg3.1/ARC; C86064; Growth factor ARC; hArc; KIAA0278; mArc; rg3.1; RGD:62037}

Host Species:
Rabbit

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Frozen)

Concentration:
1 mg/mL

Formulation:
antibody with no preservative

Gene Accession No.:
Q63053, Q7LC44, Q9WV31

Gene Symbols:
Arc

Immunogen:
Synthetic peptide corresponding to the C-terminal residues of human Arg3.1.

Regulatory Status:
RUO

Gene ID (Entrez):
11838, 23237, 54323

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Form:
Lyophilized

Img

Thermo Scientific

01-670-556

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Antigen:
CRP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Crp

Gene Alias:
Aa1249; Ab1-341; Ab2-196; Ac1-114; Ac1262; Ac2-069; acute phase protein; CRP; AI255847; Ba2-693; c reactive; C-reactive preprotein; C-reactive protein; C-reactive protein member of the pentraxin family; C-reactive protein(1-205); C-reactive protein, member of the pentraxin family; C-reactive protein, pentraxin-related; C-reactive protein, petaxin related; CRP; CRP1; CSRP; CYRP; D1S181E; DKFZp686M148; DKFZp686M149; MGC149895; MGC88244; pentraxin 1; PTX1; RP11-419N10.4

Host Species:
Goat

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
P02741

Gene Symbols:
Crp

Immunogen:
Recombinant human C-Reactive protein.

Regulatory Status:
RUO

Gene ID (Entrez):
1401

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Img

Thermo Scientific

01-670-558

--


Antigen:
Clathrin Heavy Chain

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CLTC

Gene Alias:
3110065L21Rik; CHC; CHC17; CHC22; clathrin heavy chain; clathrin heavy chain 1; Clathrin heavy chain 2; clathrin heavy chain like 1; clathrin heavy chain on chromosome 17; Clathrin heavy chain on chromosome 22; clathrin, heavy chain (Hc); clathrin, heavy chain-like 1; clathrin, heavy polypeptide (Hc); Clathrin, heavy polypeptide D; clathrin, heavy polypeptide-like 1; clathrin, heavy polypeptide-like 2; CLH17; CLH-17; CLH22; CLH-22; Cltc; CLTCL; CLTCL1; CLTCL2; CLTD; Hc; KIAA0034; R74732

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
P11442

Gene Symbols:
CLTC

Immunogen:
Synthetic peptide corresponding to residues K(619) A G L L Q R A L E H F T D L Y D I K R(638) of rat clathrin.

Regulatory Status:
RUO

Gene ID (Entrez):
54241

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized