01-670-584

NOXA Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-670-584-Each-of-1 In Stock ₹ 47,528.58

01-670-584 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

NOXA

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PMAIP1

Gene Alias

adult T cell leukemia-derived PMA-responsive; APR; Immediate-early-response protein APR; Noxa; Phorbol-12-myristate-13-acetate-induced protein 1; PMA-ind; PMA-induced protein 1; Pmaip1; Protein Noxa

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum with no preservative

Gene Accession No.

Q9JM54

Gene Symbols

PMAIP1

Immunogen

Synthetic peptide corresponding to the N-terminal residues M(1) P G R K A R R N A P V N P T R(16) of mouse Noxa.

Regulatory Status

RUO

Gene ID (Entrez)

58801

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

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Description

  • Reconstitute in 100 μL of sterile water
  • Centrifuge to remove any insoluble material
  • After reconstitution keep aliquots at -20 °C for a higher stability, and at 4 °C with an appropriate antibacterial agent
  • Glycerol (1:1) may be added for an additional stability
  • Avoid repetitive freeze/thaw cycles
  • Apoptosis is related to many diseases and development
  • The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes including p53R2, p53AIP1, and PUMA
  • A new p53 target gene, Noxa, was recently identified, which encodes a protein belonging to the subfamily of BH3-only proapoptic proteins
  • Noxa and PUMA are both transcriptional targets of p53 and BH3-only proteins
  • X-ray irradiation increased p53-dependent Noxa mRNA and protein levels
  • Noxa, when ectopically expressed, interacted with anti-apoptotic Bcl-2 family members, resulting in the activation of caspase-9
  • Noxa, like PUMA, localized to mitochondria and induces apoptosis in response to p53
  • Noxa and PUMA may represent direct mediators of p53-induced apoptosis
  • Increased levels of p53 and its target gene Noxa was found in the impaired tumor development.

Compare Similar Items

Show Difference

Img

Thermo Scientific

01-670-584

--


Antigen:
NOXA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PMAIP1

Gene Alias:
adult T cell leukemia-derived PMA-responsive; APR; Immediate-early-response protein APR; Noxa; Phorbol-12-myristate-13-acetate-induced protein 1; PMA-ind; PMA-induced protein 1; Pmaip1; Protein Noxa

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
Q9JM54

Gene Symbols:
PMAIP1

Immunogen:
Synthetic peptide corresponding to the N-terminal residues M(1) P G R K A R R N A P V N P T R(16) of mouse Noxa.

Regulatory Status:
RUO

Gene ID (Entrez):
58801

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Img

Thermo Scientific

01-670-585

--


Antigen:
NOXA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PMAIP1

Gene Alias:
adult T cell leukemia-derived PMA-responsive; APR; Immediate-early-response protein APR; Noxa; Phorbol-12-myristate-13-acetate-induced protein 1; PMA-ind; PMA-induced protein 1; Pmaip1; Protein Noxa

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
Q9JM54

Gene Symbols:
PMAIP1

Immunogen:
Synthetic peptide corresponding to residues C(75) A Q L R R I G D K V N L R Q K(90) of mouse Noxa.

Regulatory Status:
RUO

Gene ID (Entrez):
58801

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Img

Mettler Toledo™

01-670-591

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Antigen:
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Classification:
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Conjugate:
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Gene:
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Gene Alias:
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Host Species:
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Quantity:
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Formulation:
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Gene Accession No.:
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Gene Symbols:
__

Immunogen:
__

Regulatory Status:
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Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Img

Mettler Toledo™

01-670-592

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Antigen:
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Classification:
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Gene:
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Quantity:
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Formulation:
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Gene Accession No.:
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Gene Symbols:
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Immunogen:
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Content And Storage:
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Form:
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