01-670-535

ATG5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-670-535-Each-of-1 In Stock ₹ 44,790.66

01-670-535 - Each of 1

₹ 44,790.66

In Stock

Quantity

1

Base Price: ₹ 44,790.66

GST (18%): ₹ 8,062.319

Total Price: ₹ 52,852.979

Antigen

ATG5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Atg5

Gene Alias

2010107M05Rik; 3110067M24Rik; APG 5; APG5; APG5 autophagy 5 like (APG5L); APG5 autophagy 5-like protein; APG5 autophagy 5-like protein, isoform 1; APG5L; APG5-LIKE; apoptosis-specific protein; Apoptosis-specific protein (ASP); ASP; atg5; Atg-5; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); atg5.L; Atg5l; Atg5-PA; autophagy 5-like protein; autophagy protein 5; autophagy related 5; autophagy related 5 L homeolog; autophagy related 5-like protein; Autophagy-related 5; autophagy-specific gene 5; AW319544; C88337; CG1643; CG1643-PA; DmAtg5; Dmel\CG1643; Dmel_CG1643; hAPG5; hypothetical protein LOC532686; LD34980p; Paddy; XELAEV_18027227mg; zgc:100934

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Frozen), Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum with no preservative

Gene Accession No.

Q9H1Y0

Gene Symbols

Atg5

Immunogen

Synthetic peptide corresponding to the C-terminal residues of human APG-5L.

Regulatory Status

RUO

Gene ID (Entrez)

9474

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

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Description

  • Reconstitute in 100 μL of sterile water
  • Centrifuge to remove any insoluble material
  • After reconstitution keep aliquots at -20 °C for a higher stability, and at 4 °C with an appropriate antibacterial agent
  • Glycerol (1:1) may be added for an additional stability
  • Avoid repetitive freeze/thaw cycles
  • ATG5 (Autophagy Related 5) is an important element for autophagy and may play an important role in the apoptotic process
  • ATG5 is also involved in other cellular processes that include mitochondrial quality control after oxidative damage, negative regulation of the innate anti-viral immune response, lymphocyte development and proliferation, MHC II antigen presentation, and adipocyte differentiation
  • Following conjugation to ATG12, the conjugate participates in the formation of autophagosome
  • ATG5 contributes to autophagic cell death by interacting with Fas-associated protein with death domain (FADD)
  • The ATG5-ATG12 conjugate forms a cup-shaped isolation membrane that then detaches from the membrane immediately before or after autophagosome formation is completed
  • APG5 may play a role in the apoptotic process, possibly within the modified cytoskeleton
  • Further, APG5 expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity
  • The APG5-APG12 conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells
  • Diseases associated with ATG5 dysfunction include spinocerebellar ataxia.

Compare Similar Items

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Thermo Scientific

01-670-535

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Antigen:
ATG5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Atg5

Gene Alias:
2010107M05Rik; 3110067M24Rik; APG 5; APG5; APG5 autophagy 5 like (APG5L); APG5 autophagy 5-like protein; APG5 autophagy 5-like protein, isoform 1; APG5L; APG5-LIKE; apoptosis-specific protein; Apoptosis-specific protein (ASP); ASP; atg5; Atg-5; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); atg5.L; Atg5l; Atg5-PA; autophagy 5-like protein; autophagy protein 5; autophagy related 5; autophagy related 5 L homeolog; autophagy related 5-like protein; Autophagy-related 5; autophagy-specific gene 5; AW319544; C88337; CG1643; CG1643-PA; DmAtg5; Dmel\CG1643; Dmel_CG1643; hAPG5; hypothetical protein LOC532686; LD34980p; Paddy; XELAEV_18027227mg; zgc:100934

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Frozen), Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
Q9H1Y0

Gene Symbols:
Atg5

Immunogen:
Synthetic peptide corresponding to the C-terminal residues of human APG-5L.

Regulatory Status:
RUO

Gene ID (Entrez):
9474

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Img

Thermo Scientific

01-670-538

--


Antigen:
ATG5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Atg5

Gene Alias:
2010107M05Rik; 3110067M24Rik; APG 5; APG5; APG5 autophagy 5 like (APG5L); APG5 autophagy 5-like protein; APG5 autophagy 5-like protein, isoform 1; APG5L; APG5-LIKE; apoptosis-specific protein; Apoptosis-specific protein (ASP); ASP; atg5; Atg-5; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); atg5.L; Atg5l; Atg5-PA; autophagy 5-like protein; autophagy protein 5; autophagy related 5; autophagy related 5 L homeolog; autophagy related 5-like protein; Autophagy-related 5; autophagy-specific gene 5; AW319544; C88337; CG1643; CG1643-PA; DmAtg5; Dmel\CG1643; Dmel_CG1643; hAPG5; hypothetical protein LOC532686; LD34980p; Paddy; XELAEV_18027227mg; zgc:100934

Host Species:
Rabbit

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
antibody with no preservative

Gene Accession No.:
Q9H1Y0

Gene Symbols:
Atg5

Immunogen:
Synthetic peptide corresponding to the C-terminal residues of human APG-5L.

Regulatory Status:
RUO

Gene ID (Entrez):
9474

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Form:
Lyophilized

Img

Thermo Scientific

01-670-539

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Antigen:
MAP1LC3C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP1LC3C

Gene Alias:
ATG8J; Autoph; autophagy-related protein LC3 C; Autophagy-related ubiquitin-like modifier LC3 C; LC3C; LC3-like protein 2; MAP1 light chain 3-like protein 2; MAP1 light chain 3-like protein 3; MAP1A/MAP1B LC3 C; MAP1A/MAP1B light chain 3 C; MAP1LC3C; microtubule associated protein 1 light chain 3 gamma; microtubule-associated protein 1 light chain 3 gamma; Microtubule-associated proteins 1A/1B light chain 3C

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
Q9BXW4

Gene Symbols:
MAP1LC3C

Immunogen:
Synthetic peptide corresponding to the N-terminal residues of human MAP1LC3 C. The sequence is 100% conserved in in Macaca mulatta (monkey) and canine

Regulatory Status:
RUO

Gene ID (Entrez):
440738

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Img

Thermo Scientific

01-670-540

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Antigen:
Beclin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BECN1

Gene Alias:
4921513J16Rik; 5430417M23Rik; APG6; Atg6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; beclin 1; beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1 (coiled-coil, myosin-like BCL2 interacting protein); beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); beclin 1, autophagy related; beclin1; beclin-1; Beclin-1; beclin-1; Beclin-1-C 35 kDa; Beclin-1-C 37 kDa; becn1; Coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; GT197; hypothetical protein MGC73097; myosin-like BCL2 interacting protein; Protein GT197; testis secretory sperm-binding protein Li 215e; VPS30; zgc:73097

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Frozen)

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
Q14457

Gene Symbols:
BECN1

Immunogen:
Synthetic peptide corresponding to the C-terminal residues of human Beclin-1.

Regulatory Status:
RUO

Gene ID (Entrez):
8678

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized