01-674-801

CDK4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-674-801-Each-of-1 In Stock ₹ 44,705.10

01-674-801 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CDK4

Classification

Polyclonal

Formulation

PBS with 0.08% sodium azide

Gene Accession No.

P11802

Gene Symbols

Cdk4

Immunogen

TrpE-fusion protein containing the C-terminal 164 residues of human Cdk4.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Gene

Cdk4

Gene Alias

Cdk4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; cyclin-dependent kinase 4; MGC14458; p34<PSK-J3>/cdk4; PSK-J3; serine/threonine kinase; Unknown (protein for MGC:133903)

Host Species

Rabbit

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

1019

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • A suggested positive control for this product is HeLa cell lysate
  • CDK4/cyclin D3 serine/threonine kinase is dimeric protein complex
  • CDK4 is a member of the cyclin-dependent protein kinase family and is involved in the control of cell proliferation during the G1 phase of cell cycle
  • CDK4 forms a complex with the D-type cyclins and is inhibited by p16 (cyclin-dependent kinase inhibitor-2)
  • CDK4 can mediate phosphorylation of the C-terminal region of Rb protein leading to an active transcriptional repression of E2F complex
  • CDC37 and HSP90 can preferentially associate with the fraction of CDK4 not bound to D-type cyclins
  • SMAD3 is a major physiologic substrate of the G1 cyclin-dependent kinases CDK4 and CDK2
  • Although CDK6 and CDK4 can both phosphorylate multiple residues in the Rb protein, they do so with different residue selectivity in vitro; CDK6 phosphorylates Thr821 while CDK4 phosphorylates Thr826 on Rb protein.

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Thermo Scientific

01-674-801

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Antigen:
CDK4

Classification:
Polyclonal

Formulation:
PBS with 0.08% sodium azide

Gene Accession No.:
P11802

Gene Symbols:
Cdk4

Immunogen:
TrpE-fusion protein containing the C-terminal 164 residues of human Cdk4.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
Cdk4

Gene Alias:
Cdk4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; cyclin-dependent kinase 4; MGC14458; p34<PSK-J3>/cdk4; PSK-J3; serine/threonine kinase; Unknown (protein for MGC:133903)

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
1019

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

01-674-802

--


Antigen:
Bax

Classification:
Polyclonal

Formulation:
PBS with 0.08% sodium azide

Gene Accession No.:
Q07813

Gene Symbols:
BAX

Immunogen:
Synthetic peptide corresponding to residues 172 to 199 of Bax.

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
BAX

Gene Alias:
apoptosis regulator BAX; Apoptosis regulator Bcl-X; Bax; Bax zeta; BAX-ALPHA; Bax-alpha protein; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; BCL2 associated X protein; BCL2 associated X, apoptosis regulator; BCL2 like 1; BCL2-associated protein; Bcl-2-associated protein Bax; Bcl2-associated protein Bax; Bcl-2-associated X protein; BCL2-associated X protein; BCL2-associated X protein omega; BCL2L; BCL2L1; Bcl2-L-1; BCL2L4; Bcl2-L-4; BCL2-like 1; bcl-2-like protein 1; Bcl-2-like protein 4; BCLX; Bcl-X; BCL-XL/S; PPP1R52; protein phosphatase 1, regulatory subunit 52

Host Species:
Sheep

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
12028

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

01-674-804

--


Antigen:
ACVR1

Classification:
Polyclonal

Formulation:
PBS with 0.08% sodium azide

Gene Accession No.:
Q90ZK6

Gene Symbols:
ACVR1

Immunogen:
Recombinant protein corresponding to the extracellular domain of chicken ALK2.

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Chicken

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
ACVR1

Gene Alias:
activin A receptor type 1; activin A receptor type I; activin A receptor, type 1; activin A receptor, type I; activin A receptor, type II-like kinase 2; activin receptor I precursor; activin receptor type I; Activin receptor type-1; activin receptor-like kinase 2; activin type I receptor; ACTRI; ActR-I; ActRIA; Acvr; ACVR1; ACVR1A; ACVRLK2; ALK2; Alk-2; ALK2-B; Alk8; ATVR1; D330013D15Rik; FOP; hydroxyalkyl-protein kinase; serine/threonine-protein kinase receptor; serine/threonine-protein kinase receptor R1; SKR1; TGF-B superfamily receptor type I; Tgfb1; Tsk7L; TSK-7L; TSRI; TSR-I; type I TGF B receptor

Host Species:
Sheep

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
395246

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

01-674-805

--


Antigen:
TGF beta-3

Classification:
Polyclonal

Formulation:
PBS with 0.08% sodium azide

Gene Accession No.:
P16047

Gene Symbols:
TGFB3

Immunogen:
Recombinant protein corresponding to the extracellular domain of the chicken TGF III receptor.

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Chicken

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
TGFB3

Gene Alias:
ARVD; ARVD1; FLJ16571; H-TGF-b-3; LAP; Latency-associated peptide; LDS5; prepro-transforming growth factor beta-3; RNHF; TGF beta 3; Tgfb3; TGF-B3; Tgfb-3; TGF-beta3; TGF-beta-3; Transforming growth factor; transforming growth factor beta 3; transforming growth factor beta precursor; transforming growth factor beta-3; Transforming growth factor beta-3 proprotein; transforming growth factor, beta 3; transforming growth factor-beta3

Host Species:
Sheep

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
396438

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid