01-676-517
TLR2 Monoclonal Antibody (mT2.4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-676-517-Each-of-1 | In Stock | ₹ 52,918.86 |
01-676-517 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,918.86
GST (18%): ₹ 9,525.395
Total Price: ₹ 62,444.255
Antigen
TLR2
Classification
Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with 0.1% BSA and no preservative
Gene Accession No.
Q9QUN7
Gene Symbols
Tlr2
Immunogen
Murine TLR2 peptide
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b
Applications
ELISA, Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone
mT2.4
Conjugate
Unconjugated
Gene
Tlr2
Gene Alias
CD282; Ly105; TIL4; Tlr2; TLR-2; toll like receptor 2; toll/interleukin-1 receptor-like protein 4; Toll-like receptor; toll-like receptor 2; toll-like receptor 2 variant 1; toll-like receptor 2 variant 2; toll-like-receptor 2, exon 1a_; Toll-like-receptor, exon 1b; Toll-like-receptor, exon 1b_; Toll-like-receptor2, exon 1a
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
24088
Content And Storage
4° C
Form
Liquid
Related Products
Description
- MA1-40080 detects TLR2 from mouse samples
- MA1-40080 inhibits murine TLR2-mediated cell activation
- It masks the lipopeptide binding site in the recombinant extracellular domain of TLR2 (TLR2ECD) and does not hinder the receptor complex formation
- MA1-40080 reacts with the native TLR2 protein and not with denatured TLR2 protein
- Furthermore the antibody stains overexpressed, as well as endogenous cell surface- and intracellular mouse TLR2
- MA1-40080 has been successfully used in flow cytometry, ELISA, function assays and immunohistochemistry (paraffin and frozen) applications
- The MA1-40080 immunogen is mouse TLR2
- Endotoxin <24 EU/mg
- TLR2 is a member of the Toll-like receptor (TLR) family which play a fundamental role in pathogen recognition and activation of innate immunity
- TLR proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-kappa-B
- TLR2 can form heterodimers with either TLR1 or TLR6, and as a heterodimer, can recognize a variety of bacterial and mycoplasma lipoproteins respectively
- TLRs are highly conserved from Drosophila to humans and share structural and functional similarities
- The various TLRs exhibit different patterns of expression
- TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB
- TLR2 aids in the recognition of pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
- Ten human homologs of TLRs (TLR1-10) have been described
- TLR2 is expressed in human cells such as tonsils, microglia, lymph nodes, and appendices, activated B-cells in germinal centers
- CD14+ monocytes express the highest level of TLR2 followed by CD15+ granulocytes, CD19+ B-cells, and CD3+ T-cells
- The expression of TLR2 on different cell types are regulated by different immune response modifiers
- For example, LPS, GM-CSF, IL-1, and IL-10 up regulates TLR2 whereas IL-4, IFN-gamma, and TNF down regulate TLR2 expression in monocytes.
Compare Similar Items
Show Difference
Antigen: TLR2
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 0.1% BSA and no preservative
Gene Accession No.: Q9QUN7
Gene Symbols: Tlr2
Immunogen: Murine TLR2 peptide
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b
Applications: ELISA, Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: mT2.4
Conjugate: Unconjugated
Gene: Tlr2
Gene Alias: CD282; Ly105; TIL4; Tlr2; TLR-2; toll like receptor 2; toll/interleukin-1 receptor-like protein 4; Toll-like receptor; toll-like receptor 2; toll-like receptor 2 variant 1; toll-like receptor 2 variant 2; toll-like-receptor 2, exon 1a_; Toll-like-receptor, exon 1b; Toll-like-receptor, exon 1b_; Toll-like-receptor2, exon 1a
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 24088
Content And Storage: 4° C
Form: Liquid
Antigen:
TLR2
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 0.1% BSA and no preservative
Gene Accession No.:
Q9QUN7
Gene Symbols:
Tlr2
Immunogen:
Murine TLR2 peptide
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b
Applications:
ELISA, Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone:
mT2.4
Conjugate:
Unconjugated
Gene:
Tlr2
Gene Alias:
CD282; Ly105; TIL4; Tlr2; TLR-2; toll like receptor 2; toll/interleukin-1 receptor-like protein 4; Toll-like receptor; toll-like receptor 2; toll-like receptor 2 variant 1; toll-like receptor 2 variant 2; toll-like-receptor 2, exon 1a_; Toll-like-receptor, exon 1b; Toll-like-receptor, exon 1b_; Toll-like-receptor2, exon 1a
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
24088
Content And Storage:
4° C
Form:
Liquid
Antigen: BPI
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.: P17213
Gene Symbols: BPI
Immunogen: Full length human BPI.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA
Clone: 4H5
Conjugate: Unconjugated
Gene: BPI
Gene Alias: 9230105K17Rik; Bactericidal permeability-increasing protein; bactericidal permeablility increasing protein; bactericidal/permeability-increasing protein; BPI; BPI fold containing family D, member 1; BPIFD1; CAP 57; rBPI; recombinant BPI holoprotein, rBPI; RP13-218F6_A.1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 671
Content And Storage: 4° C
Form: Liquid
Antigen:
BPI
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.:
P17213
Gene Symbols:
BPI
Immunogen:
Full length human BPI.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA
Clone:
4H5
Conjugate:
Unconjugated
Gene:
BPI
Gene Alias:
9230105K17Rik; Bactericidal permeability-increasing protein; bactericidal permeablility increasing protein; bactericidal/permeability-increasing protein; BPI; BPI fold containing family D, member 1; BPIFD1; CAP 57; rBPI; recombinant BPI holoprotein, rBPI; RP13-218F6_A.1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
671
Content And Storage:
4° C
Form:
Liquid
Antigen: Polymyxin B
Classification: Monoclonal
Concentration: >200 μg/mL
Formulation: tissue culture supernatant with 0.02% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: Polymixin B.
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Bacteria
Product Type: Antibody
Isotype: IgM
Applications: ELISA, Western Blot
Clone: 45
Conjugate: Unconjugated
Gene: __
Gene Alias: PMB
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C
Form: Liquid
Antigen:
Polymyxin B
Classification:
Monoclonal
Concentration:
>200 μg/mL
Formulation:
tissue culture supernatant with 0.02% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Polymixin B.
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Bacteria
Product Type:
Antibody
Isotype:
IgM
Applications:
ELISA, Western Blot
Clone:
45
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
PMB
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C
Form:
Liquid
Antigen: MBL2
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 0.1% BSA and no preservative
Gene Accession No.: P11226
Gene Symbols: MBL2
Immunogen: Serum isolated human RaRF
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen)
Clone: 3E7
Conjugate: Unconjugated
Gene: MBL2
Gene Alias: 27 kDa mannan-binding protein monomeric subunit; Ab2-001; Ab2-011; cMBl; COLEC1; collectin; Collectin1; collectin-1; c-type lectin; HSMBPC; L-MBP; mannan-binding lectin; mannan-binding lectin C; mannan-binding protein; mannose binding lectin (C); mannose binding lectin 2; mannose binding lectin 2 (protein C); mannose binding lectin, liver (A); mannose binding lectin, liver (C); mannose-binding lectin; mannose-binding lectin (protein C) 2; mannose-binding lectin (protein C) 2, soluble; mannose-binding lectin (protein C) 2, soluble (opsonic defect); mannose-binding lectin 2, soluble (opsonic defect); mannose-binding lectin C; mannose-binding lectin precursor protein; mannose-binding lectin-C; mannose-binding protein; Mannose-binding protein C; mannose-binding protein C (liver); mbl; MBL2; MBL2D; MBL-C; MBP; MBP1; MBPC; MBP-C; MBPD; MGC116832; MGC116833; pMBP-27; RA-reactive factor P28A subunit; ra-reactive factor polysaccharide-binding component p28A; RaRF p28A; RARF/P28A; serum protein; MBL; soluble mannose-binding lectin
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 4153
Content And Storage: 4° C
Form: Liquid
Antigen:
MBL2
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 0.1% BSA and no preservative
Gene Accession No.:
P11226
Gene Symbols:
MBL2
Immunogen:
Serum isolated human RaRF
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen)
Clone:
3E7
Conjugate:
Unconjugated
Gene:
MBL2
Gene Alias:
27 kDa mannan-binding protein monomeric subunit; Ab2-001; Ab2-011; cMBl; COLEC1; collectin; Collectin1; collectin-1; c-type lectin; HSMBPC; L-MBP; mannan-binding lectin; mannan-binding lectin C; mannan-binding protein; mannose binding lectin (C); mannose binding lectin 2; mannose binding lectin 2 (protein C); mannose binding lectin, liver (A); mannose binding lectin, liver (C); mannose-binding lectin; mannose-binding lectin (protein C) 2; mannose-binding lectin (protein C) 2, soluble; mannose-binding lectin (protein C) 2, soluble (opsonic defect); mannose-binding lectin 2, soluble (opsonic defect); mannose-binding lectin C; mannose-binding lectin precursor protein; mannose-binding lectin-C; mannose-binding protein; Mannose-binding protein C; mannose-binding protein C (liver); mbl; MBL2; MBL2D; MBL-C; MBP; MBP1; MBPC; MBP-C; MBPD; MGC116832; MGC116833; pMBP-27; RA-reactive factor P28A subunit; ra-reactive factor polysaccharide-binding component p28A; RaRF p28A; RARF/P28A; serum protein; MBL; soluble mannose-binding lectin
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
4153
Content And Storage:
4° C
Form:
Liquid