14-738-537

IL-38 Monoclonal Antibody (H127C), eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 14-738-537-Each-of-1 In Stock ₹ 1,17,388.32

14-738-537 - Each of 1

₹ 1,17,388.32

In Stock

Quantity

1

Base Price: ₹ 1,17,388.32

GST (18%): ₹ 21,129.898

Total Price: ₹ 1,38,518.218

Antigen

IL-38

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q8WWZ1

Gene Symbols

IL1F10

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

84639

Content And Storage

4° C

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

H127C

Conjugate

Unconjugated

Gene

IL1F10

Gene Alias

family of interleukin 1-theta; FIL1 theta; FIL1T; FIL1-theta; FKSG75; IL-1 theta; Il1f10; IL-1F10; IL-1F10 (canonical form IL-1F10a); IL1HY2; IL-1HY2; IL1-theta; IL38; IL-38; interleukin 1 family member 10 (theta); interleukin 1 family, member 10; interleukin 1 family, member 10 (theta); interleukin 1 family, member 7; interleukin-1 family member 10; Interleukin-1 HY2; interleukin-1 receptor antagonist FKSG75; interleukin-1 receptor antagonist-like FIL1 theta; Interleukin-1 theta; Interleukin-38; UNQ6119/PRO20041

Host Species

Mouse

Quantity

2 mg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b κ

Related Products

Img

Invitrogen

50-112-9364

--

Img

Invitrogen

50-112-8691

--

Img

Invitrogen

14-712-285

--

Img

Invitrogen

14-704-285

--

Img

Invitrogen

14-120-637

--

Img

Invitrogen

16-704-582

--

Img

Invitrogen

16-706-938

--

Img

Invitrogen

50-121-56

--

Description

  • Description: The monoclonal antibody H127C recognizes human IL-38
  • IL-38 is a member of the Interleukin-1 family (IL-1F) and shares homology with IL-1R antagonist (IL-1Ra) and IL-36R antagonist (IL-36Ra)
  • IL-38 is expressed mostly in the skin and proliferating B cells of the tonsil and is also present at low levels in the heart and placenta
  • IL-38 functions as an anti-inflammatory cytokine that inhibits IL-36 by binding to IL-36R and also inhibits the production of IL-17 and IL-22
  • Gene polymorphisms of IL-38 are associated with psoriatic arthritis, ankylosing spondylitis, and heart disease
  • Applications Reported: This H127C antibody has been reported for use in flow cytometric analysis, immunoprecipitation, western blotting, ELISA, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections
  • Applications Tested: This H127C antibody has been tested by immunohistochemistry on formalin-fixed paraffin embedded human tissue using low pH antigen retrieval and can be used at less than or equal to 0.1 μg/mL
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Purity: Greater than 90%, as determined by SDS-PAGE
  • Aggregation: Less than 10%, as determined by HPLC
  • Filtration: 0.2 μm post-manufacturing filtered
  • The cytokine IL-1 is responsible for initiating a variety of activities through the activation of transcription factors, NF-kappa B and AP-1, thereby promoting host response to injury or infection
  • IL-1F10 (Interleukin-1 family member 10), also known as FIL1T, IL1HY2 or FKSG75, is highly expressed in the skin, spleen and proliferating B-cells of the tonsil
  • IL-1F10 binds soluble IL-1 receptor type 1, and is one of nine Interleukin 1 families clustered on chromosome 2, where it is thought to participate in the regulation of adapted and innate immune responses
  • IL-1F10 and IL-1RN polymorphisms may play an important role in the susceptibility to developing rheumatoid arthritis.

Compare Similar Items

Show Difference

Img

Invitrogen

14-738-537

--


Antigen:
IL-38

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q8WWZ1

Gene Symbols:
IL1F10

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84639

Content And Storage:
4° C

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
H127C

Conjugate:
Unconjugated

Gene:
IL1F10

Gene Alias:
family of interleukin 1-theta; FIL1 theta; FIL1T; FIL1-theta; FKSG75; IL-1 theta; Il1f10; IL-1F10; IL-1F10 (canonical form IL-1F10a); IL1HY2; IL-1HY2; IL1-theta; IL38; IL-38; interleukin 1 family member 10 (theta); interleukin 1 family, member 10; interleukin 1 family, member 10 (theta); interleukin 1 family, member 7; interleukin-1 family member 10; Interleukin-1 HY2; interleukin-1 receptor antagonist FKSG75; interleukin-1 receptor antagonist-like FIL1 theta; Interleukin-1 theta; Interleukin-38; UNQ6119/PRO20041

Host Species:
Mouse

Quantity:
2 mg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b κ

Img

Fischer Scientific

14-740Q

--


Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
Funnel Support Arm

Isotype:
__

Img

Invitrogen™

14-750-100

--


Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
The BLOCK-iT™ Alexa Fluor™ Red Fluorescent Control is provided at a concentration of 20 μM. Store at -20°C. Guaranteed stable for 12 months when properly stored.

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
2 x 125 μL

Primary or Secondary:
__

Target Species:
__

Product Type:
Red fluorescent transfection control

Isotype:
__

Img

Fischer Scientific

14-750Q

--


Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
Each

Primary or Secondary:
__

Target Species:
__

Product Type:
Plate

Isotype:
__