14-974-737
Desmin Monoclonal Antibody (DE-U-10), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 14-974-737-Each-of-1 | In Stock | ₹ 1,17,901.68 |
14-974-737 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,17,901.68
GST (18%): ₹ 21,222.302
Total Price: ₹ 1,39,123.982
Antigen
Desmin
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
O62654, P02540, P02542, P17661, P31001, P48675
Gene Symbols
DES
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100328890, 100764990, 101097010, 101117308, 102180712, 13346, 1674, 280765, 395906, 396725, 64362
Content And Storage
4° C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
DE-U-10
Conjugate
Unconjugated
Gene
DES
Gene Alias
CMD1I; CSM1; CSM2; DES; Desmin; desmin-like protein; FLJ12025; FLJ39719; FLJ41013; FLJ41793; I79_018932; intermediate filament protein; LGMD2R; MFM1; muscle-specific intermediate filament desmin; muscle-specific intermediate filament protein; mutant desmin p.K241E; SCPNK; similar to desmin
Host Species
Mouse
Quantity
2 mg
Primary or Secondary
Primary
Target Species
Bovine, Chicken, Feline, Goat, Hamster, Human, Mouse, Ovine, Porcine, Rabbit, Rat
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- The MAb DE-U-10 recognizes desmin
- Desmin is the protein subunit of class-III intermediate filaments
- Desmin is found predominantly in skeletal, cardiac, and smooth muscle
- Desmin plays a role in muscle cell development and differentiation, muscle cell architecture and structure, and mitochondrial function
- Desmin forms scaffolds around the Z-disk of sarcomeres in muscle cells
- Desmin knockout mice exhibit defects in skeletal, smooth, and cardiac muscle and have impaired mitochondrial function
- Mutations in Desmin result in conditions such as desmin-related myopathy (DRM), cardiomyopathy dilated type 1I (CMD1I), and neurogenic scapuloperoneal syndrome Kaeser type (Kaeser syndrome)
- The DE-U-10 antibody recognizes human, mouse, rat, feline, bovine, goat, hamster, sheep, porcine, rabbit, and chicken desmin
- The DE-U-10 antibody will also label tumors derived from muscle tissue, such as leiomyomas and rhabdomyosarcomas
- Desmin (approximately 53 kDa) exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle)
- Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation
- In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk
- The expression pattern of desmin in smooth muscle is much more heterogenous
- Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue, i.e
- rhabdomyosarcomas and leiomyosarcomas
- Furthermore, during myocard dysfunction dramatic changes in the distribution of desmin have been observed.
Compare Similar Items
Show Difference
Antigen: Desmin
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O62654, P02540, P02542, P17661, P31001, P48675
Gene Symbols: DES
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100328890, 100764990, 101097010, 101117308, 102180712, 13346, 1674, 280765, 395906, 396725, 64362
Content And Storage: 4° C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: DE-U-10
Conjugate: Unconjugated
Gene: DES
Gene Alias: CMD1I; CSM1; CSM2; DES; Desmin; desmin-like protein; FLJ12025; FLJ39719; FLJ41013; FLJ41793; I79_018932; intermediate filament protein; LGMD2R; MFM1; muscle-specific intermediate filament desmin; muscle-specific intermediate filament protein; mutant desmin p.K241E; SCPNK; similar to desmin
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Bovine, Chicken, Feline, Goat, Hamster, Human, Mouse, Ovine, Porcine, Rabbit, Rat
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Desmin
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O62654, P02540, P02542, P17661, P31001, P48675
Gene Symbols:
DES
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100328890, 100764990, 101097010, 101117308, 102180712, 13346, 1674, 280765, 395906, 396725, 64362
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
DE-U-10
Conjugate:
Unconjugated
Gene:
DES
Gene Alias:
CMD1I; CSM1; CSM2; DES; Desmin; desmin-like protein; FLJ12025; FLJ39719; FLJ41013; FLJ41793; I79_018932; intermediate filament protein; LGMD2R; MFM1; muscle-specific intermediate filament desmin; muscle-specific intermediate filament protein; mutant desmin p.K241E; SCPNK; similar to desmin
Host Species:
Mouse
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Bovine, Chicken, Feline, Goat, Hamster, Human, Mouse, Ovine, Porcine, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: APP (Amyloid Precursor Protein)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P05067, P08592, P12023
Gene Symbols: APP
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11820, 351, 54226
Content And Storage: 4° C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone: 22C11
Conjugate: Unconjugated
Gene: APP
Gene Alias: A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; amyloid A4; Amyloid b precursor protein; amyloid beta (A4) precursor protein; amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; Amyloid β precursor protein; Amyloid-beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; betaApp; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTFgamma; CVAP; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; P3(40); P3(42); Pan-Abeta; peptidase nexin-II; PN2; PN-II; PreA4; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; testicular tissue protein Li 2
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
APP (Amyloid Precursor Protein)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P05067, P08592, P12023
Gene Symbols:
APP
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11820, 351, 54226
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone:
22C11
Conjugate:
Unconjugated
Gene:
APP
Gene Alias:
A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; amyloid A4; Amyloid b precursor protein; amyloid beta (A4) precursor protein; amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; Amyloid β precursor protein; Amyloid-beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; betaApp; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTFgamma; CVAP; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; P3(40); P3(42); Pan-Abeta; peptidase nexin-II; PN2; PN-II; PreA4; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; testicular tissue protein Li 2
Host Species:
Mouse
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: IDO
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P14902
Gene Symbols: Ido1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3620
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: V1NC3IDO
Conjugate: Unconjugated
Gene: Ido1
Gene Alias: EC 1.13.11.52; IDO; IDO1; IDO-1; INDO; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; indoleamine-pyrrole 2,3-dioxygenase
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
IDO
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P14902
Gene Symbols:
Ido1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3620
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
V1NC3IDO
Conjugate:
Unconjugated
Gene:
Ido1
Gene Alias:
EC 1.13.11.52; IDO; IDO1; IDO-1; INDO; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; indoleamine-pyrrole 2,3-dioxygenase
Host Species:
Mouse
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: Somatostatin
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P60041, P60042, P61278
Gene Symbols: SST
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20604, 24797, 6750
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Clone: ICDCLS
Conjugate: Unconjugated
Gene: SST
Gene Alias: Antrin; Growth hormone release-inhibiting factor; Neuronostatin; NST; preprosomatostatin; prepro-somatostatin; SMST; SOM; Somatostatin; somatostatin 28; somatostatin-14; Somatostatin-28; somatotropin release-inhibiting factor; SRIF; SS; SS-14; SS-28; Sst; SST-14
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Somatostatin
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P60041, P60042, P61278
Gene Symbols:
SST
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20604, 24797, 6750
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Clone:
ICDCLS
Conjugate:
Unconjugated
Gene:
SST
Gene Alias:
Antrin; Growth hormone release-inhibiting factor; Neuronostatin; NST; preprosomatostatin; prepro-somatostatin; SMST; SOM; Somatostatin; somatostatin 28; somatostatin-14; Somatostatin-28; somatotropin release-inhibiting factor; SRIF; SS; SS-14; SS-28; Sst; SST-14
Host Species:
Mouse
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ