15-477-742
FOXP3 Monoclonal Antibody (236A/E7), PE-Cyanine5, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 15-477-742-Each-of-1 | In Stock | ₹ 39,272.04 |
15-477-742 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,272.04
GST (18%): ₹ 7,068.967
Total Price: ₹ 46,341.007
Antigen
FOXP3
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.
Q9BZS1
Gene Symbols
Foxp3
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
50943, 574303
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
236A/E7
Conjugate
PE-Cyanine5
Gene
Foxp3
Gene Alias
AIID, DIETER, forkhead box P3, forkhead box protein P3, Forkhead box protein P3 41 kDa form, Forkhead box protein P3, C-terminally processed, forkhead/winged helix transcription factor 3, Foxp3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, immunodeficiency, polyendocrinopathy, enteropathy, X-linked, IPEX, JM2, MGC141961, MGC141963, PIDX, regulatory protein Foxp3, RGD1562112, RP23-54C14.1, scurfin, scurfy, sf, XPID
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human, Non-human Primate, Rhesus Monkey
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The 236A/E7 antibody reacts with human foxp3 protein also known as FORKHEAD BOX P3, SCURFIN, and JM2; cross reactivity of this antibody to other proteins has not been determined
- Foxp3, a 49-55 kDa protein, is a member of the forkhead/winged-helix family of transcriptional regulators, and was identified as the gene defective in 'scurfy' (sf) mice
- Constitutive high expression of Foxp3 mRNA has been shown in CD4+CD25+ regulatory T cells (Treg cells), and ectopic expression of foxp3 in CD4+CD25- cells imparts a Treg phenotype in these cells
- Intracellular staining and flow cytometric analysis of freshly isolated human peripheral blood mononuclear cells (PBMCs) with the 236A/E7 antibody using the Foxp3 Staining Buffer Set (cat
- 00-5523) and protocol reveals staining of the CD4+CD25^bright population
- The epitope from 236A/E7 is different from that of PCH101 (cat
- 72-5776)
- Applications Reported: This 236A/E7 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 236A/E7 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells using the Foxp3/Transcription Factor Staining Buffer Set (Product No
- 00-5523-00) and protocol
- FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis
- FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells
- FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells
- Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice
- In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome
- Transcript variants of FOXP3 encoding different isoforms have been identified
- In human breast and colon cancer cells, expression of FOXP3 is regulated by p53 in response to the DNA damage.
Compare Similar Items
Show Difference
Antigen: FOXP3
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: Q9BZS1
Gene Symbols: Foxp3
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 50943, 574303
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 236A/E7
Conjugate: PE-Cyanine5
Gene: Foxp3
Gene Alias: AIID, DIETER, forkhead box P3, forkhead box protein P3, Forkhead box protein P3 41 kDa form, Forkhead box protein P3, C-terminally processed, forkhead/winged helix transcription factor 3, Foxp3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, immunodeficiency, polyendocrinopathy, enteropathy, X-linked, IPEX, JM2, MGC141961, MGC141963, PIDX, regulatory protein Foxp3, RGD1562112, RP23-54C14.1, scurfin, scurfy, sf, XPID
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Non-human Primate, Rhesus Monkey
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
FOXP3
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
Q9BZS1
Gene Symbols:
Foxp3
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
50943, 574303
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
236A/E7
Conjugate:
PE-Cyanine5
Gene:
Foxp3
Gene Alias:
AIID, DIETER, forkhead box P3, forkhead box protein P3, Forkhead box protein P3 41 kDa form, Forkhead box protein P3, C-terminally processed, forkhead/winged helix transcription factor 3, Foxp3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, immunodeficiency, polyendocrinopathy, enteropathy, X-linked, IPEX, JM2, MGC141961, MGC141963, PIDX, regulatory protein Foxp3, RGD1562112, RP23-54C14.1, scurfin, scurfy, sf, XPID
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: EOMES
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O54839
Gene Symbols: Eomes
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13813
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: Dan11mag
Conjugate: PE-Cyanine5
Gene: Eomes
Gene Alias: C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
EOMES
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O54839
Gene Symbols:
Eomes
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13813
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
Dan11mag
Conjugate:
PE-Cyanine5
Gene:
Eomes
Gene Alias:
C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: EOMES
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O54839
Gene Symbols: Eomes
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13813
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: Dan11mag
Conjugate: PE-Cyanine5
Gene: Eomes
Gene Alias: C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
EOMES
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O54839
Gene Symbols:
Eomes
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13813
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
Dan11mag
Conjugate:
PE-Cyanine5
Gene:
Eomes
Gene Alias:
C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: __
Applications: __
Clone: __
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Quantity: __
Primary or Secondary: __
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Product Type: SCBA
Isotype: __
Antigen:
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Classification:
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Concentration:
__
Formulation:
__
Gene Accession No.:
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Gene Symbols:
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Purification Method:
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Clone:
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Conjugate:
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Gene:
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Quantity:
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Primary or Secondary:
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Product Type:
SCBA
Isotype:
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