50-112-4365
FOXP3 Monoclonal Antibody (150D/E4), eFluor™ 660, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-4365-Each-of-1 | In Stock | ₹ 34,224.00 |
50-112-4365 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,224.00
GST (18%): ₹ 6,160.32
Total Price: ₹ 40,384.32
Antigen
FOXP3
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
Q99JB6, Q9BZS1
Gene Symbols
Foxp3
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20371, 317382, 50943
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
150D/E4
Conjugate
eFluor 660
Gene
Foxp3
Gene Alias
AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: eBioscience offers a panel of monoclonal antibodies to different epitopes of human/primate and mouse/rat Foxp3 protein, providing useful tools for investigating the complete expression pattern of Foxp3 at the protein level, and discerning the precise subsets of Foxp3+ cells
- Other antibodies to Foxp3 available from eBioscience, which have been used significantly in scientific literature, include the anti-human Foxp3 PCH101 (cat
- 72-5776) and ebio7979 (cat
- 12-7979), and the anti-mouse/rat Foxp3 FJK-16s (cat
- 72-5775)
- The 150D/E4 has been mapped to the splice region in Exon 2 found in human cells
- The splicing of this region has not been shown to occur in mouse
- Characterization of this antibody to the splice variant has been limited to epitope mapping
- It should be noted that other antibodies such as PCH101 and 236A/E7 will recognize both the spliced and full length forms of the Foxp3 protein and stain more intensely than 150D/E4 and FJK-16s in human cells
- The 150D/E4 antibody reacts with mouse/rat/human Foxp3 also known as FORKHEAD BOX P3, SCURFIN, and JM2
- Cross reactivity of this antibody to other proteins has not been determined
- Foxp3, a 49-55 kDa protein, is a member of the forkhead/winged-helix family of transcriptional regulators, and was identified as the gene defective in 'scurfy' (sf) mice
- FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis
- FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells
- FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells
- Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice
- In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome
- Transcript variants of FOXP3 encoding different isoforms have been identified
- In human breast and colon cancer cells, expression of FOXP3 is regulated by p53 in response to the DNA damage.
Compare Similar Items
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Antigen: FOXP3
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: Q99JB6, Q9BZS1
Gene Symbols: Foxp3
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20371, 317382, 50943
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 150D/E4
Conjugate: eFluor 660
Gene: Foxp3
Gene Alias: AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
FOXP3
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q99JB6, Q9BZS1
Gene Symbols:
Foxp3
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20371, 317382, 50943
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
150D/E4
Conjugate:
eFluor 660
Gene:
Foxp3
Gene Alias:
AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: F4/80
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q61549
Gene Symbols: ADGRE1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13733
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: BM8
Conjugate: eFluor 660
Gene: ADGRE1
Gene Alias: ADGRE1; Adhesion G protein-coupled receptor E1; Adhesion G protein-coupled receptor E2; cell surface glycoprotein EMR1; cell surface glycoprotein F4/80; DD7A5-7; EGF-like module containing, mucin-like, hormone receptor-like 1; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-TM7; Emr1; EMR1 hormone receptor; F4/80; Gpf480; Ly71; lymphocyte antigen 71; TM7LN3
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
F4/80
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q61549
Gene Symbols:
ADGRE1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13733
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
BM8
Conjugate:
eFluor 660
Gene:
ADGRE1
Gene Alias:
ADGRE1; Adhesion G protein-coupled receptor E1; Adhesion G protein-coupled receptor E2; cell surface glycoprotein EMR1; cell surface glycoprotein F4/80; DD7A5-7; EGF-like module containing, mucin-like, hormone receptor-like 1; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-TM7; Emr1; EMR1 hormone receptor; F4/80; Gpf480; Ly71; lymphocyte antigen 71; TM7LN3
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: EOMES
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O54839
Gene Symbols: Eomes
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13813
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: Dan11mag
Conjugate: eFluor 660
Gene: Eomes
Gene Alias: C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
EOMES
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O54839
Gene Symbols:
Eomes
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13813
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
Dan11mag
Conjugate:
eFluor 660
Gene:
Eomes
Gene Alias:
C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Armenian Hamster IgG
Classification: __
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: __
Gene Symbols: __
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Control, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry
Clone: eBio299Arm
Conjugate: eFluor 660
Gene: __
Gene Alias: IgG; Immunoglobulin G; ImmunoglobulinG
Host Species: Armenian Hamster
Quantity: 100 μg
Primary or Secondary: Isotype Control (Primary)
Target Species: Not Applicable
Product Type: __
Isotype: IgG
Antigen:
Armenian Hamster IgG
Classification:
__
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Control, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry
Clone:
eBio299Arm
Conjugate:
eFluor 660
Gene:
__
Gene Alias:
IgG; Immunoglobulin G; ImmunoglobulinG
Host Species:
Armenian Hamster
Quantity:
100 μg
Primary or Secondary:
Isotype Control (Primary)
Target Species:
Not Applicable
Product Type:
__
Isotype:
IgG