17-582-580
T-bet Monoclonal Antibody (eBio4B10 (4B10)), APC, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 17-582-580-Each-of-1 | In Stock | ₹ 18,309.84 |
17-582-580 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 18,309.84
GST (18%): ₹ 3,295.771
Total Price: ₹ 21,605.611
Antigen
T-bet
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q9JKD8, Q9UL17
Gene Symbols
Tbx21
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
30009, 57765, 694044
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
eBio4B10 (4B10)
Conjugate
APC
Gene
Tbx21
Gene Alias
HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
Host Species
Mouse
Quantity
25μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rhesus Monkey
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The eBio4B10 monoclonal antibody reacts with mouse and human T-bet
- T-bet is a Th1-specific T-box transcription factor critical to the development of the Th1 CD4+ T cell lineage
- This is known based on the observations that T-Bet deficient mice have impaired Th1 cell development, and that ectopic expression of T-Bet results in development skewed to the Th1 lineage
- T-Bet expression is induced by the Th1 cytokine IFN gamma, and T-Bet also regulates the expression of IFN gamma, likely, at least in part, through the modification of DNA accessibility and histone remodeling
- In addition to IFN gamma, T-Bet is also known to regulate the expression of IL-12R beta and IL-2
- Moreover, T-Bet plays a role in class-switch recombination in B-cells
- Applications Reported: This eBio4B10 (4B10, 4-B10) antibody has been reported for use in intracellular staining followed by flow cytometric analysis
- Applications Tested: This eBio4B10 (4B10, 4-B10) antibody has been tested by intracellular stainign and flow cytometric analysis of normal human peripheral blood cells using the Foxp3/Transcription Factor Buffer Set (cat
- 00-5523) and protocol
- Please see Best Protocol section; (refer to Protocol B: One step protocol for intracellular (nuclear) proteins)
- This can be used at less than or equal to 0.25 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- T-bet, also known as TBX21, is a T-cell specific transcription factor containing a single T-box DNA-binding domain
- It controls the expression of the TH1 cytokine, interferon-gamma
- Both Th1 and Th17 cells are crucial in immune regulation and autoimmune disease development
- T-bet initiates Th1 lineage development from naive Th precursor cells and directs T cell differentiation to Th1 versus Th17
- T-bet is cooperating with Stat4 (signal tranducer and activator of transcription 4) in programming chromatin architecture for Th1 gene expression
- Genetic variations in T-bet are associated with susceptibility to aspirin-induced asthma and nasal polyps.
Compare Similar Items
Show Difference
Antigen: T-bet
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9JKD8, Q9UL17
Gene Symbols: Tbx21
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 30009, 57765, 694044
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: eBio4B10 (4B10)
Conjugate: APC
Gene: Tbx21
Gene Alias: HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
Host Species: Mouse
Quantity: 25μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rhesus Monkey
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
T-bet
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9JKD8, Q9UL17
Gene Symbols:
Tbx21
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
30009, 57765, 694044
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
eBio4B10 (4B10)
Conjugate:
APC
Gene:
Tbx21
Gene Alias:
HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
Host Species:
Mouse
Quantity:
25μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: T-bet
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9JKD8, Q9UL17
Gene Symbols: Tbx21
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 30009, 57765, 694044
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: eBio4B10 (4B10)
Conjugate: APC
Gene: Tbx21
Gene Alias: HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
Host Species: Mouse
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rhesus Monkey
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
T-bet
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9JKD8, Q9UL17
Gene Symbols:
Tbx21
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
30009, 57765, 694044
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
eBio4B10 (4B10)
Conjugate:
APC
Gene:
Tbx21
Gene Alias:
HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
Host Species:
Mouse
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: Siglec-G
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q80ZE3
Gene Symbols: Siglecg
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 243958
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: SH2.1
Conjugate: APC
Gene: Siglecg
Gene Alias: 9830164H23; A630096C01Rik; mSiglec-G; sialic acid binding Ig-like lectin 10; sialic acid binding Ig-like lectin G; sialic acid-binding Ig-like lectin 10; Sialic acid-binding Ig-like lectin G; Siglec; Siglec 10; Siglec10; Siglec-10; Siglecg; Siglec-G
Host Species: Mouse
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Siglec-G
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q80ZE3
Gene Symbols:
Siglecg
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
243958
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
SH2.1
Conjugate:
APC
Gene:
Siglecg
Gene Alias:
9830164H23; A630096C01Rik; mSiglec-G; sialic acid binding Ig-like lectin 10; sialic acid binding Ig-like lectin G; sialic acid-binding Ig-like lectin 10; Sialic acid-binding Ig-like lectin G; Siglec; Siglec 10; Siglec10; Siglec-10; Siglecg; Siglec-G
Host Species:
Mouse
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD369 (Clec7a, Dectin-1)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q6QLQ4
Gene Symbols: Clec7a
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 56644
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: bg1fpj
Conjugate: APC
Gene: Clec7a
Gene Alias: Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD369 (Clec7a, Dectin-1)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q6QLQ4
Gene Symbols:
Clec7a
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
56644
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
bg1fpj
Conjugate:
APC
Gene:
Clec7a
Gene Alias:
Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ