HLA-DR Monoclonal Antibody (L243), APC, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 17-995-242-Each-of-1 | In Stock | ₹ 20,021.04 |
17-995-242 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 20,021.04
GST (18%): ₹ 3,603.787
Total Price: ₹ 23,624.827
Antigen
HLA-DR
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.
P01903, P01911, P04233, P13762, P18470, P79483, Q30154
Gene Symbols
CD74, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
102131412, 3122, 3123, 3125, 3126, 3127, 474860, 479329, 710820, 972
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
L243
Conjugate
APC
Gene
HLA-DRB4
Gene Alias
AI323765, BLA-DRB3, BOLA-DRA, BoLA-DR-alpha, BoLA-DRB, BOLA-DRB3, BoLA-DRB3 protein, BoLA-DRB3.2, Bota-DRB01, Bota-DRB02, Bota-DRB04, Bota-DRB07, Bota-DRB21, Bota-DRB22, bovine leukocyte antigen, Cd74, CD74 antigen, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated), CD74 molecule, Cd74 molecule, major histocompatibility complex, class II invariant chain, class II-associated invariant chain peptide, CLIP, Clone P2-beta-3, DASS-397D15.1, DHLAG, dinucleotide microsatellite, DLA class II histocompatibility antigen, DR-1 beta chain, DLA DRBB1 beta chain, DLA-DR beta, DLA-DRB1, DLA-DRBB1, DR beta-5, DR beta-chain antigen binding domain, DR-16, DR2-beta-2, DR4, DR-4, DR7, DR9, DR-9, DRB, DRB1, DRB1 transplantation antigen, DRB3, DRB4, DRBB1, DR-beta chain, DR-beta chain MHC class II, DRw10, Dw2, DW2.2/DR2.2, E-alpha-f, FLJ51114, FLJ75017, FLJ76359, gamma chain of class II antigens, H-2 class II histocompatibility antigen gamma chain, H-2 class II histocompatibility antigen, E-D alpha chain, H-2 class II histocompatibility antigen, E-K alpha chain, H-2 class II histocompatibility antigen, E-U alpha chain, H-2Ea, H2-Ea, H2-Ea-ps, H2-IE-alpha, histocompatibility 2, class II antigen E alpha, histocompatibility 2, class II antigen E alpha, pseudogene, histocompatibility antigen HLA-DR alpha, histocompatibility complex, class II, DR beta 3, histocompatibility: class II antigens, gamma chain of, HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DR beta 3 chain, HLA class II histocompatibility antigen, DR beta 4 chain, HLA class II histocompatibility antigen, DR beta 5 chain, HLA class II histocompatibility antigen, DR-1 beta chain, HLA class II histocompatibility antigen, DR-5 beta chain, HLA class II histocompatibility antigen, DRB1-15 beta chain, HLA class II histocompatibility antigen, DRB1-16 beta chain, HLA class II histocompatibility antigen, DRB1-3 chain, HLA class II histocompatibility antigen, DRB1-7 beta chain, HLA class II histocompatibility antigen, DRB1-9 beta chain, HLADG, HLA-DR antigens-associated invariant chain, HLA-DR1B, HLA-DR3B, HLA-DR4B, HLA-DRA, HLA-DRA1, HLA-DRB, HLA-DRB1, HLA-DRB2, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-DR-gamma, human leucocyte antigen DRB1, human leucocyte antigen DRB3, human leucocyte antigen DRB4, human leucocyte antigen DRB5, ia antigen-associated invariant chain, Ia3, Ia-3, Ia-associated invariant chain, Ia-GAMMA, I-E alpha MHC class II, I-Ealpha, II, integral membrane glycoprotein, invariant gamma chain, invariant polypeptide of major histocompatibility complex, class II antigen-associated, INVG34, LA-DRB, leukocyte antigen, leukocyte antigen class II, leukocyte antigen DRB3, lymphocyte antigen DRB1, major histocompatibility complex class II DR-beta chain, major histocompatibility complex, class II, DR alpha, major histocompatibility complex, class II, DR alpha precursor, major histocompatibility complex, class II, DR beta 1, major histocompatibility complex, class II, DR beta 3, major histocompatibility complex, class II, DR beta 4, major histocompatibility complex, class II, DR beta 4 precursor, major histocompatibility complex, class II, DR beta 5, major histocompatibility complex, class II, DRB3, MHC cell surface glycoprotein, MHC class I antigen, MHC class II antigen, MHC class II antigen beta chain, MHC class II antigen BoLA-DRB3, MHC class II antigen DR beta 3 chain, MHC class II antigen DRA, MHC class II antigen DRB1*15, MHC class II antigen DRB1*16, MHC class II antigen DRB1*3, MHC class II antigen DRB1*9, MHC class II antigen DRB3, MHC class II antigen DRB4, MHC class II antigen DRB5, MHC class II antigen E alpha, MHC class II antigen HLA-DR-beta, MHC class II DLA DRB1 beta chain, MHC class II DLA-DRB, MHC class II DLA-DR-beta-1, MHC class II DR beta 1, MHC class II DR beta chain, MHC class II DR beta-chain, MHC class II DR-ALPHA
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Canine, Cynomolgus Monkey, Human, Non-human Primate, Rhesus Monkey
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The L243 mAb reacts with the human major histocompatibility complex (MHC) class II, HLA-DR
- HLA-DR is expressed on the surface of human antigen presenting cells (APC) including B cells, monocytes, macrophages, DCs, and activated T cells
- HLA-DR is a heterodimeric transmembrane protein composed of alpha and beta subunits and plays an important role in the presentation of peptides to CD4+ T lymphocytes
- The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each other's respective epitopes
- Applications Reported: This L243 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This L243 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
- This may be used at 5 μL (0.5 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser HLA-DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of a 36 kDa alpha chain (DRA) and 27 kDa beta chain (DRB)
- The alpha chain gene contains 5 exons
- Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail
- DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5
- Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities
- Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
- HLA-DR is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes
- Three loci, DR, DQ and DP, encode the major expressed products of the human class II region
- The human MHC class II molecules bind intracellularly processed peptides, present them to T-helper cells, and have a critical role in the initiation of the immune response
- HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
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Show Difference
Antigen: HLA-DR
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P01903, P01911, P04233, P13762, P18470, P79483, Q30154
Gene Symbols: CD74, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 102131412, 3122, 3123, 3125, 3126, 3127, 474860, 479329, 710820, 972
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: L243
Conjugate: APC
Gene: HLA-DRB4
Gene Alias: AI323765, BLA-DRB3, BOLA-DRA, BoLA-DR-alpha, BoLA-DRB, BOLA-DRB3, BoLA-DRB3 protein, BoLA-DRB3.2, Bota-DRB01, Bota-DRB02, Bota-DRB04, Bota-DRB07, Bota-DRB21, Bota-DRB22, bovine leukocyte antigen, Cd74, CD74 antigen, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated), CD74 molecule, Cd74 molecule, major histocompatibility complex, class II invariant chain, class II-associated invariant chain peptide, CLIP, Clone P2-beta-3, DASS-397D15.1, DHLAG, dinucleotide microsatellite, DLA class II histocompatibility antigen, DR-1 beta chain, DLA DRBB1 beta chain, DLA-DR beta, DLA-DRB1, DLA-DRBB1, DR beta-5, DR beta-chain antigen binding domain, DR-16, DR2-beta-2, DR4, DR-4, DR7, DR9, DR-9, DRB, DRB1, DRB1 transplantation antigen, DRB3, DRB4, DRBB1, DR-beta chain, DR-beta chain MHC class II, DRw10, Dw2, DW2.2/DR2.2, E-alpha-f, FLJ51114, FLJ75017, FLJ76359, gamma chain of class II antigens, H-2 class II histocompatibility antigen gamma chain, H-2 class II histocompatibility antigen, E-D alpha chain, H-2 class II histocompatibility antigen, E-K alpha chain, H-2 class II histocompatibility antigen, E-U alpha chain, H-2Ea, H2-Ea, H2-Ea-ps, H2-IE-alpha, histocompatibility 2, class II antigen E alpha, histocompatibility 2, class II antigen E alpha, pseudogene, histocompatibility antigen HLA-DR alpha, histocompatibility complex, class II, DR beta 3, histocompatibility: class II antigens, gamma chain of, HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DR beta 3 chain, HLA class II histocompatibility antigen, DR beta 4 chain, HLA class II histocompatibility antigen, DR beta 5 chain, HLA class II histocompatibility antigen, DR-1 beta chain, HLA class II histocompatibility antigen, DR-5 beta chain, HLA class II histocompatibility antigen, DRB1-15 beta chain, HLA class II histocompatibility antigen, DRB1-16 beta chain, HLA class II histocompatibility antigen, DRB1-3 chain, HLA class II histocompatibility antigen, DRB1-7 beta chain, HLA class II histocompatibility antigen, DRB1-9 beta chain, HLADG, HLA-DR antigens-associated invariant chain, HLA-DR1B, HLA-DR3B, HLA-DR4B, HLA-DRA, HLA-DRA1, HLA-DRB, HLA-DRB1, HLA-DRB2, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-DR-gamma, human leucocyte antigen DRB1, human leucocyte antigen DRB3, human leucocyte antigen DRB4, human leucocyte antigen DRB5, ia antigen-associated invariant chain, Ia3, Ia-3, Ia-associated invariant chain, Ia-GAMMA, I-E alpha MHC class II, I-Ealpha, II, integral membrane glycoprotein, invariant gamma chain, invariant polypeptide of major histocompatibility complex, class II antigen-associated, INVG34, LA-DRB, leukocyte antigen, leukocyte antigen class II, leukocyte antigen DRB3, lymphocyte antigen DRB1, major histocompatibility complex class II DR-beta chain, major histocompatibility complex, class II, DR alpha, major histocompatibility complex, class II, DR alpha precursor, major histocompatibility complex, class II, DR beta 1, major histocompatibility complex, class II, DR beta 3, major histocompatibility complex, class II, DR beta 4, major histocompatibility complex, class II, DR beta 4 precursor, major histocompatibility complex, class II, DR beta 5, major histocompatibility complex, class II, DRB3, MHC cell surface glycoprotein, MHC class I antigen, MHC class II antigen, MHC class II antigen beta chain, MHC class II antigen BoLA-DRB3, MHC class II antigen DR beta 3 chain, MHC class II antigen DRA, MHC class II antigen DRB1*15, MHC class II antigen DRB1*16, MHC class II antigen DRB1*3, MHC class II antigen DRB1*9, MHC class II antigen DRB3, MHC class II antigen DRB4, MHC class II antigen DRB5, MHC class II antigen E alpha, MHC class II antigen HLA-DR-beta, MHC class II DLA DRB1 beta chain, MHC class II DLA-DRB, MHC class II DLA-DR-beta-1, MHC class II DR beta 1, MHC class II DR beta chain, MHC class II DR beta-chain, MHC class II DR-ALPHA
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Canine, Cynomolgus Monkey, Human, Non-human Primate, Rhesus Monkey
Product Type: Antibody
Isotype: IgG2a κ
Antigen: MHC I Free Chain
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: __
Gene Symbols: __
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: A4
Conjugate: APC
Gene: __
Gene Alias: MHC Free
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Quantity: __
Primary or Secondary: __
Target Species: __
Product Type: __
Isotype: __
