200020366
ZO-1 Recombinant Mouse Monoclonal Antibody (ZO1-1A12), Alexa Fluor™ Plus 555, Invitrogen™
Mouse Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
ZO-1
Concentration
1.0 mg/mL
Classification
Recombinant Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5
Gene Alias
DKFZp686M05161, I79_005485, MGC133289, OTTHUMP00000174520, Tight junction protein 1, tight junction protein 1 (zona occludens 1), tight junction protein ZO-1, Tjp1, zo1, ZO-1, ZO-1 MDCK, zona occludens 1, zona occludens protein 1, zonula occludens 1, zonula occludens 1 protein, zonula occludens protein 1
Gene Symbols
TJP1
Isotype
IgG1
Purification Method
Protein A/G
Gene
TJP1
Clone
ZO1-1A12
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)
Conjugate
Alexa Fluor Plus 555
Host Species
Mouse
Target Species
Human
Gene Accession No.
Q07157
Gene ID (Entrez)
7082
Immunogen
Human recombinant ZO-1 fusion protein encompassing amino acids 334-634
Primary or Secondary
Primary
Content And Storage
4°, C, store in dark, DO NOT FREEZE!
Related Products
Description
- ZO-1 forms complexes with either ZO-2 or ZO-3
- In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction
- ZO-1 expression is significantly reduced in many breast cancer lines
- ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue
- ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions
- ZO-1 may be involved in signal transduction at cell-cell junctions
- Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene
- Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.
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Antigen: ZO-1
Concentration: 1.0 mg/mL
Classification: Recombinant Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5
Gene Alias: DKFZp686M05161, I79_005485, MGC133289, OTTHUMP00000174520, Tight junction protein 1, tight junction protein 1 (zona occludens 1), tight junction protein ZO-1, Tjp1, zo1, ZO-1, ZO-1 MDCK, zona occludens 1, zona occludens protein 1, zonula occludens 1, zonula occludens 1 protein, zonula occludens protein 1
Gene Symbols: TJP1
Isotype: IgG1
Purification Method: Protein A/G
Gene: TJP1
Clone: ZO1-1A12
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)
Conjugate: Alexa Fluor Plus 555
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q07157
Gene ID (Entrez): 7082
Immunogen: Human recombinant ZO-1 fusion protein encompassing amino acids 334-634
Primary or Secondary: Primary
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Antigen:
ZO-1
Concentration:
1.0 mg/mL
Classification:
Recombinant Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5
Gene Alias:
DKFZp686M05161, I79_005485, MGC133289, OTTHUMP00000174520, Tight junction protein 1, tight junction protein 1 (zona occludens 1), tight junction protein ZO-1, Tjp1, zo1, ZO-1, ZO-1 MDCK, zona occludens 1, zona occludens protein 1, zonula occludens 1, zonula occludens 1 protein, zonula occludens protein 1
Gene Symbols:
TJP1
Isotype:
IgG1
Purification Method:
Protein A/G
Gene:
TJP1
Clone:
ZO1-1A12
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)
Conjugate:
Alexa Fluor Plus 555
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q07157
Gene ID (Entrez):
7082
Immunogen:
Human recombinant ZO-1 fusion protein encompassing amino acids 334-634
Primary or Secondary:
Primary
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Antigen: ZO-1
Concentration: 1.0 mg/mL
Classification: Recombinant Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5
Gene Alias: DKFZp686M05161, I79_005485, MGC133289, OTTHUMP00000174520, Tight junction protein 1, tight junction protein 1 (zona occludens 1), tight junction protein ZO-1, Tjp1, zo1, ZO-1, ZO-1 MDCK, zona occludens 1, zona occludens protein 1, zonula occludens 1, zonula occludens 1 protein, zonula occludens protein 1
Gene Symbols: TJP1
Isotype: IgG1
Purification Method: Protein A/G
Gene: TJP1
Clone: ZO1-1A12
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)
Conjugate: Alexa Fluor Plus 647
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q07157
Gene ID (Entrez): 7082
Immunogen: Human recombinant ZO-1 fusion protein encompassing amino acids 334-634
Primary or Secondary: Primary
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Antigen:
ZO-1
Concentration:
1.0 mg/mL
Classification:
Recombinant Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5
Gene Alias:
DKFZp686M05161, I79_005485, MGC133289, OTTHUMP00000174520, Tight junction protein 1, tight junction protein 1 (zona occludens 1), tight junction protein ZO-1, Tjp1, zo1, ZO-1, ZO-1 MDCK, zona occludens 1, zona occludens protein 1, zonula occludens 1, zonula occludens 1 protein, zonula occludens protein 1
Gene Symbols:
TJP1
Isotype:
IgG1
Purification Method:
Protein A/G
Gene:
TJP1
Clone:
ZO1-1A12
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)
Conjugate:
Alexa Fluor Plus 647
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q07157
Gene ID (Entrez):
7082
Immunogen:
Human recombinant ZO-1 fusion protein encompassing amino acids 334-634
Primary or Secondary:
Primary
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Antigen: Occludin
Concentration: 1.0 mg/mL
Classification: Recombinant Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5
Gene Alias: AI503564, BLCPMG, Occludin, occludin 1B, Ocl, Ocln, phosphatase 1, regulatory subunit 115, PPP1R115, tight junction protein occludin, tight junction structural protein
Gene Symbols: OCLN
Isotype: IgG1 κ
Purification Method: Protein A/G
Gene: OCLN
Clone: OC-3F10
Applications: Flow Cytometry, Immunocytochemistry
Conjugate: Alexa Fluor Plus 488
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q16625
Gene ID (Entrez): 100506658
Immunogen: GST fusion protein consisting of the C-terminal region (∽150aa) of human occludin.
Primary or Secondary: Primary
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Antigen:
Occludin
Concentration:
1.0 mg/mL
Classification:
Recombinant Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5
Gene Alias:
AI503564, BLCPMG, Occludin, occludin 1B, Ocl, Ocln, phosphatase 1, regulatory subunit 115, PPP1R115, tight junction protein occludin, tight junction structural protein
Gene Symbols:
OCLN
Isotype:
IgG1 κ
Purification Method:
Protein A/G
Gene:
OCLN
Clone:
OC-3F10
Applications:
Flow Cytometry, Immunocytochemistry
Conjugate:
Alexa Fluor Plus 488
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q16625
Gene ID (Entrez):
100506658
Immunogen:
GST fusion protein consisting of the C-terminal region (∽150aa) of human occludin.
Primary or Secondary:
Primary
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Antigen: Occludin
Concentration: 1.0 mg/mL
Classification: Recombinant Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5
Gene Alias: AI503564, BLCPMG, Occludin, occludin 1B, Ocl, Ocln, phosphatase 1, regulatory subunit 115, PPP1R115, tight junction protein occludin, tight junction structural protein
Gene Symbols: OCLN
Isotype: IgG1 κ
Purification Method: Protein A/G
Gene: OCLN
Clone: OC-3F10
Applications: Flow Cytometry, Immunocytochemistry
Conjugate: Alexa Fluor Plus 488
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q16625
Gene ID (Entrez): 100506658
Immunogen: GST fusion protein consisting of the C-terminal region (∽150aa) of human occludin.
Primary or Secondary: Primary
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Antigen:
Occludin
Concentration:
1.0 mg/mL
Classification:
Recombinant Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5
Gene Alias:
AI503564, BLCPMG, Occludin, occludin 1B, Ocl, Ocln, phosphatase 1, regulatory subunit 115, PPP1R115, tight junction protein occludin, tight junction structural protein
Gene Symbols:
OCLN
Isotype:
IgG1 κ
Purification Method:
Protein A/G
Gene:
OCLN
Clone:
OC-3F10
Applications:
Flow Cytometry, Immunocytochemistry
Conjugate:
Alexa Fluor Plus 488
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q16625
Gene ID (Entrez):
100506658
Immunogen:
GST fusion protein consisting of the C-terminal region (∽150aa) of human occludin.
Primary or Secondary:
Primary
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!