200020368

Occludin Recombinant Mouse Monoclonal Antibody (OC-3F10), Alexa Fluor™ Plus 488, Invitrogen™

Mouse Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Occludin

Concentration

1.0 mg/mL

Classification

Recombinant Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5

Gene Alias

AI503564, BLCPMG, Occludin, occludin 1B, Ocl, Ocln, phosphatase 1, regulatory subunit 115, PPP1R115, tight junction protein occludin, tight junction structural protein

Gene Symbols

OCLN

Isotype

IgG1 κ

Purification Method

Protein A/G

Gene

OCLN

Clone

OC-3F10

Applications

Flow Cytometry, Immunocytochemistry

Conjugate

Alexa Fluor Plus 488

Host Species

Mouse

Target Species

Human

Gene Accession No.

Q16625

Gene ID (Entrez)

100506658

Immunogen

GST fusion protein consisting of the C-terminal region (∽150aa) of human occludin.

Primary or Secondary

Primary

Content And Storage

4°, C, store in dark, DO NOT FREEZE!

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Description

  • Description Occludin is a 65 kDa protein that can exist in a variety of phosphorylated forms, ranging up to approximately 82 kDa
  • Occludin is thought to be involved in regulating both the localization and the function of occludin
  • Polyunsaturated fatty acids are known to up-regulate occludin expression, increasing the transendothelial cell resistance and reducing the cellular permeability to large molecules
  • The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly and continuously expressed at cell-cell contact sites, whereas non-neural tissues show lower expression and discontinuous distribution
  • Overall structural features of the occludin protein are highly conserved in all the species examined
  • Under-expression of tight junction proteins, including occludin, is a key molecular abnormality responsible for the increased permeability of tumor endothelial tight junctions, which contributes to brain tumor edemas.

Compare Similar Items

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Img

Fischer Scientific

200020368

Mouse Recombinant Monoclonal Antibo...


Antigen:
Occludin

Concentration:
1.0 mg/mL

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5

Gene Alias:
AI503564, BLCPMG, Occludin, occludin 1B, Ocl, Ocln, phosphatase 1, regulatory subunit 115, PPP1R115, tight junction protein occludin, tight junction structural protein

Gene Symbols:
OCLN

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
OCLN

Clone:
OC-3F10

Applications:
Flow Cytometry, Immunocytochemistry

Conjugate:
Alexa Fluor Plus 488

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q16625

Gene ID (Entrez):
100506658

Immunogen:
GST fusion protein consisting of the C-terminal region (∽150aa) of human occludin.

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Img

Fischer Scientific

200020369

Mouse Recombinant Monoclonal Antibo...


Antigen:
Occludin

Concentration:
1.0 mg/mL

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5

Gene Alias:
AI503564, BLCPMG, Occludin, occludin 1B, Ocl, Ocln, phosphatase 1, regulatory subunit 115, PPP1R115, tight junction protein occludin, tight junction structural protein

Gene Symbols:
OCLN

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
OCLN

Clone:
OC-3F10

Applications:
Flow Cytometry, Immunocytochemistry

Conjugate:
Alexa Fluor Plus 594

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q16625

Gene ID (Entrez):
100506658

Immunogen:
GST fusion protein consisting of the C-terminal region (∽150aa) of human occludin.

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Img

Fischer Scientific

200020370

Mouse Recombinant Monoclonal Antibo...


Antigen:
Occludin

Concentration:
1.0 mg/mL

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5

Gene Alias:
AI503564, BLCPMG, Occludin, occludin 1B, Ocl, Ocln, phosphatase 1, regulatory subunit 115, PPP1R115, tight junction protein occludin, tight junction structural protein

Gene Symbols:
OCLN

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
OCLN

Clone:
OC-3F10

Applications:
Flow Cytometry, Immunocytochemistry

Conjugate:
Alexa Fluor Plus 647

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q16625

Gene ID (Entrez):
100506658

Immunogen:
GST fusion protein consisting of the C-terminal region (∽150aa) of human occludin.

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Img

Fischer Scientific

200020371

Syrian Hamster Monoclonal Antibody...


Antigen:
KLRG1

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
2F1, 2F1-Ag, CLEC15A, C-type lectin domain family 15 member A, C-type lectin domain family 15, member A, ITIM-containing receptor MAFA-L, killer cell lectin like receptor G1, killer cell lectin-like receptor subfamily G member 1, killer cell lectin-like receptor subfamily G, member 1, Klrg1, Mafa, MAFA-2F1, MAFAL, MAFA-L, MAFA-LIKE, MAFA-like receptor, Mast cell function-associated antigen, mast cell function-associated antigen (ITIM-containing), mast cell function-associated antigen 2F1, natural killer cell receptor

Gene Symbols:
Klrg1

Isotype:
IgG

Purification Method:
Affinity chromatography

Gene:
Klrg1

Clone:
2F1

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 395

Host Species:
Syrian Hamster

Target Species:
Mouse

Gene Accession No.:
O88713

Gene ID (Entrez):
50928

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!