200020417

CD366 (TIM3) Monoclonal Antibody (F38-2E2), Brilliant Violet™ 605, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CD366 (TIM3)

Concentration

5 μL/Test

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias

CD366, FLJ14428, Havcr2, HAVcr-2, Hepatitis A virus cellular receptor 2, hepatitis A virus cellular receptor 2 homolog, kidney injury molecule-3, KIM-3, sCD366, soluble CD366, soluble TIM 3, T cell immunoglobulin mucin 3, T cell immunoglobulin mucin-3, T-cell immunoglobulin and mucin domain containing 3, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin family member 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, Tim3, TIM-3, TIMD3, TIMD-3

Gene Symbols

Havcr2

Primary or Secondary

Primary

Content And Storage

4°, C, store in dark, DO NOT FREEZE!

Clone

F38-2E2

Applications

Flow Cytometry

Conjugate

Brilliant Violet 605

Host Species

Mouse

Target Species

Human

Gene Accession No.

Q8TDQ0

Gene ID (Entrez)

84868

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Gene

Havcr2

Related Products

Img

Fischer Scientific

200020303

Mouse Monoclonal Antibody...

Img

Fischer Scientific

200020303

Mouse Monoclonal Antibody...

Img

Fischer Scientific

200020414

Syrian Hamster Monoclonal Antibody...

Img

Fischer Scientific

200020432

Syrian Hamster Monoclonal Antibody...

Img

Fischer Scientific

200020401

Syrian Hamster Monoclonal Antibody...

Img

Fischer Scientific

200020371

Syrian Hamster Monoclonal Antibody...

Img

Fischer Scientific

200020395

Syrian Hamster Monoclonal Antibody...

Img

Fischer Scientific

200020398

Syrian Hamster Monoclonal Antibody...

Description

  • TIM3 (Hepatitis A virus cellular receptor 2, HAVCR2, T-cell immunoglobulin, mucin-dmain containing-3) is a 281 amino acid long, Type-1 Th1- specific cell surface glycoprotein expressed on terminally differentiated CD4+Th1 and CD8+Tc1 cells
  • TIM3 consists of an IgV-like domain, a mucin-like domain in the extracellular region, and a conserved Tyrosine phosphorylation motif in the cytoplasmic region
  • TIM3 is involved in macrophage activation and induction of autoimmune diseases
  • Further, TIM3 down-regulates aggressive Th1-mediated immune responses and facilitates in the development of immune tolerance
  • Pathological significance of TIM3 has been attributed to Experimental autoimmune encephalomyelitis (EAE), a Th-1 dependent autoimmune disease, and also enhances the severity of experimental autoimmune encephalomyelitis in mice.

Compare Similar Items

Show Difference

Img

Fischer Scientific

200020417

Mouse Monoclonal Antibody...


Antigen:
CD366 (TIM3)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
CD366, FLJ14428, Havcr2, HAVcr-2, Hepatitis A virus cellular receptor 2, hepatitis A virus cellular receptor 2 homolog, kidney injury molecule-3, KIM-3, sCD366, soluble CD366, soluble TIM 3, T cell immunoglobulin mucin 3, T cell immunoglobulin mucin-3, T-cell immunoglobulin and mucin domain containing 3, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin family member 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, Tim3, TIM-3, TIMD3, TIMD-3

Gene Symbols:
Havcr2

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Clone:
F38-2E2

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 605

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q8TDQ0

Gene ID (Entrez):
84868

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Gene:
Havcr2

Img

Fischer Scientific

200020418

Mouse Monoclonal Antibody...


Antigen:
IgM

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
AGM1, IGHM, immunoglobulin heavy constant mu, MU, VH

Gene Symbols:
IGHM

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Clone:
SA-DA4

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 605

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P01871

Gene ID (Entrez):
3507

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Gene:
IGHM

Img

Fischer Scientific

200020420

Rat Monoclonal Antibody...


Antigen:
CD45R (B220)

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
B220, Cd45, CD45 antigen, CD45R, GP180, Lca, L-CA, leucocyte common antigen, leukocyte common antigen, leukocyte common antigen A, leukocyte common antigen B, loc, LY5, Ly-5, Lymphocyte antigen 5, lymphocyte common antigen, Lyt-4, membrane tyrosine phosphatase, protein tyrosine phosphatase receptor type C, protein tyrosine phosphatase, receptor type C, protein tyrosine phosphatase, receptor type, C, protein tyrosine phosphatase, receptor type, c polypeptide, Protein tyrosine phosphatase, receptor-type, c polypeptide, Ptprc, Receptor-type tyrosine-protein phosphatase C, RT7, T200, T200 glycoprotein, T200 leukocyte common antigen

Gene Symbols:
PTPRC

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Clone:
RA3-6B2

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 480

Host Species:
Rat

Target Species:
Human, Mouse

Gene Accession No.:
P06800, P08575

Gene ID (Entrez):
19264, 5788

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Gene:
PTPRC

Img

Fischer Scientific

200020422

Mouse Monoclonal Antibody...


Antigen:
SIGLEC7

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
Adhesion inhibitory receptor molecule 1, adhesion inhibitory receptor molecule 1, siglec-7, AIRM1, AIRM-1, CD328, CDw328, D-siglec, p75, p75/ AIRM-1, p75/AIRM1, QA79, QA79 membrane protein, sialic acid binding Ig like lectin 7, sialic acid binding Ig-like lectin 7, sialic acid binding immunoglobulin-like lectin 7, sialic acid-binding Ig-like lectin 7, Siglec, SIGLEC19P, SIGLEC7, SIGLEC-7, SIGLECP2

Gene Symbols:
SIGLEC7

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Clone:
D5

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Rat

Gene Accession No.:
Q9Y286

Gene ID (Entrez):
27036

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
SIGLEC7