25-514-942
CD85d (ILT4) Monoclonal Antibody (42D1), PE-Cyanine7, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 25-514-942-Each-of-1 | In Stock | ₹ 34,224.00 |
25-514-942 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,224.00
GST (18%): ₹ 6,160.32
Total Price: ₹ 40,384.32
Antigen
CD85d (ILT4)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.
Q8N423
Gene Symbols
LILRB2
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10288
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
42D1
Conjugate
PE-Cyanine7
Gene
LILRB2
Gene Alias
CD85 antigen-like family member D, CD85D, CD85d antigen, Ig-like transcript 4, ILT4, ILT-4, leucocyte Ig-like receptor B2, leukocyte immunoglobulin like receptor B2, leukocyte immunoglobulin-like receptor subfamily B member 2, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3, LILRB2, Lilrb3, LIR2, LIR-2, LIR2CD85D, MIR10, MIR-10, MIR10LILRA6, monocyte/macrophage immunoglobulin-like receptor 10, myeloid inhibitory receptor 10, Neutrophil immunoglobulin-like receptor 1, Nilr1, NILR-1, paired-Ig-like receptor B, Pirb, type 1 one-pass transmembrane Ig-like receptor
Host Species
Rat
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The monoclonal antibody 42D1 recognizes the CD85d protein also known as ILT4, LIR-2
- It is a member of the ILT (immunoglobulin-like transcript)/ LIR (leukocyte Ig-like receptor), MIR (monocytes Ig-like receptor) family
- CD85d is a 110 kDa single transmembrane receptor with 3 Ig-like domains and a long cytoplasmic domain containing ITIMs (immunoreceptor tyrosine-based inhibitory motifs)
- Expression is confined to monocytes, macrophages and dendritic cells
- The ligand for CD85d is non-classical class I HLA-G, -B and G1
- Upon ligand binding, tyrosine phosphatase SHP-1 interacts with the ITIM
- Interaction of HLA-G with ILT4/CD85d is thought to contribute to tolerance during fetal implantation
- Additionally, it is the levels of ILT3 and ILT4 on DCs that suggests a role in organ allograft rejection
- Crosslinking of the receptor with the monoclonal antibody 42D1 inhibits calcium flux as well as enhancing HLA-G tetramer staining and restoring the stimulating activity of tolerogenic DC
- Applications Reported: This 42D1 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 42D1 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
- This may be used at 5 μL (0.5 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- LILRB2 (ILT4) gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4
- The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs)
- The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response
- It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity
- Multiple transcript variants encoding different isoforms have been found for this gene.
Compare Similar Items
Show Difference
Antigen: CD85d (ILT4)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: Q8N423
Gene Symbols: LILRB2
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10288
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 42D1
Conjugate: PE-Cyanine7
Gene: LILRB2
Gene Alias: CD85 antigen-like family member D, CD85D, CD85d antigen, Ig-like transcript 4, ILT4, ILT-4, leucocyte Ig-like receptor B2, leukocyte immunoglobulin like receptor B2, leukocyte immunoglobulin-like receptor subfamily B member 2, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3, LILRB2, Lilrb3, LIR2, LIR-2, LIR2CD85D, MIR10, MIR-10, MIR10LILRA6, monocyte/macrophage immunoglobulin-like receptor 10, myeloid inhibitory receptor 10, Neutrophil immunoglobulin-like receptor 1, Nilr1, NILR-1, paired-Ig-like receptor B, Pirb, type 1 one-pass transmembrane Ig-like receptor
Host Species: Rat
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD85d (ILT4)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
Q8N423
Gene Symbols:
LILRB2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10288
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
42D1
Conjugate:
PE-Cyanine7
Gene:
LILRB2
Gene Alias:
CD85 antigen-like family member D, CD85D, CD85d antigen, Ig-like transcript 4, ILT4, ILT-4, leucocyte Ig-like receptor B2, leukocyte immunoglobulin like receptor B2, leukocyte immunoglobulin-like receptor subfamily B member 2, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3, LILRB2, Lilrb3, LIR2, LIR-2, LIR2CD85D, MIR10, MIR-10, MIR10LILRA6, monocyte/macrophage immunoglobulin-like receptor 10, myeloid inhibitory receptor 10, Neutrophil immunoglobulin-like receptor 1, Nilr1, NILR-1, paired-Ig-like receptor B, Pirb, type 1 one-pass transmembrane Ig-like receptor
Host Species:
Rat
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD218a (IL-18Ra)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q61098
Gene Symbols: Il18r1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16182
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: P3TUNYA
Conjugate: PE-Cyanine7
Gene: Il18r1
Gene Alias: CD218 antigen-like family member A, CD218a, CDw218a, cytokine receptor, IL1 receptor-related protein, Il18r1, IL-18R1, IL-18R-1, IL18RA, Il18ralpha, IL-18R-alpha, IL18Ralpha2, IL1RRP, IL-1Rrp, IL1R-rp, interleukin 1 receptor related protein, interleukin 18 receptor 1, Interleukin-18, interleukin-18 receptor 1, Interleukin-18 receptor alpha
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD218a (IL-18Ra)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q61098
Gene Symbols:
Il18r1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16182
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
P3TUNYA
Conjugate:
PE-Cyanine7
Gene:
Il18r1
Gene Alias:
CD218 antigen-like family member A, CD218a, CDw218a, cytokine receptor, IL1 receptor-related protein, Il18r1, IL-18R1, IL-18R-1, IL18RA, Il18ralpha, IL-18R-alpha, IL18Ralpha2, IL1RRP, IL-1Rrp, IL1R-rp, interleukin 1 receptor related protein, interleukin 18 receptor 1, Interleukin-18, interleukin-18 receptor 1, Interleukin-18 receptor alpha
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: One vialStore in refrigerator (2–8°C).
Form: Powder
Applications: __
Clone: __
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Gene: __
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Host Species: __
Quantity: 100 mg
Primary or Secondary: __
Target Species: __
Product Type: Proteinase K
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
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Regulatory Status:
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Gene ID (Entrez):
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Content And Storage:
One vialStore in refrigerator (2–8°C).
Form:
Powder
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
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Host Species:
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Quantity:
100 mg
Primary or Secondary:
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Target Species:
__
Product Type:
Proteinase K
Isotype:
__
Antigen: __
Classification: __
Concentration: >40 U/mg
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: One tube Proteinase KStore in refrigerator (2–8°C).
Form: Powder
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Quantity: 1 g
Primary or Secondary: __
Target Species: __
Product Type: Proteinase K
Isotype: __
Antigen:
__
Classification:
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Concentration:
>40 U/mg
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
__
Regulatory Status:
__
Gene ID (Entrez):
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Content And Storage:
One tube Proteinase KStore in refrigerator (2–8°C).
Form:
Powder
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Quantity:
1 g
Primary or Secondary:
__
Target Species:
__
Product Type:
Proteinase K
Isotype:
__