25-576-642

TCR V beta F1 Monoclonal Antibody (8A3), PE-Cyanine7, eBioscience™, Invitrogen™

Manufacturer: eBioscience

Select a Size

Pack Size SKU Availability Price
Each 25-576-642-Each In Stock ₹ 32,311.73

25-576-642 - Each

₹ 32,311.73

In Stock

Quantity

1

Base Price: ₹ 32,311.73

GST (18%): ₹ 5,816.111

Total Price: ₹ 38,127.841

Antigen

TCR V beta F1

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

0

Gene Symbols

TRB

Immunogen

Human TCR beta chain constant region

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

8A3

Conjugate

PE-Cyanine7

Gene

TRB

Gene Alias

T cell receptor beta locus; tcr beta f1; TCRB; TRB; TRB@

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6957

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

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Description

  • This 8A3 monoclonal antibody recognizes human TCR beta F1, a common framework determit on the beta-subunit of the T cell receptor
  • Expression of TCR beta F1 has been described as a potential diagnostic marker indicating a favorable outcome for tumor patients with not otherwise specified Nodal Peripheral T-cell Lymphoma (PTCL-NOS)
  • Furthermore, a lack of surface and cytoplasmic TCR beta F1 was also found in small cell variant of T-cell prolymphocytic Leukemia
  • This antibody will not stain the native form of the TCR and will require fixing and permeabilizing cells
  • Applications Reported: This 8A3 antibody has been reported for use in flow cytometric analysis, immunofluorescent staining of frozen tissue sections, and immunocytochemistry
  • Applications Tested: This 8A3 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
  • This may be used at 5 μL (0.125 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Light sensitivity: This tandem dye is sensitive to photo-induced oxidation
  • Please protect this vial and stained samples from light
  • Fixation: Samples can be stored in IC Fixation Buffer (Product No
  • 00-8222) (100 μL of cell sample + 100 μL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product No
  • The T Cell Receptor alpha beta (TCRab) is a heterodimeric membrane receptor that consists of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 proteins
  • TCRab participates in the activation of T-cells in response to an antigen presented in the context of MHC
  • Engagement of the TCRab initiates signaling cascades that μgtimately result in cellular proliferation, differentiation, cytokine production, and/or activation-induced cell death
  • These signaling cascades regulate T-cell development, homeostasis, activation, acquisition of effector functions and apoptosis
  • Cells expressing TCRab constitute the vast majority of T cells in both human and mouse.

Compare Similar Items

Show Difference

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eBioscience

25-576-642

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Antigen:
TCR V beta F1

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
0

Gene Symbols:
TRB

Immunogen:
Human TCR beta chain constant region

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
8A3

Conjugate:
PE-Cyanine7

Gene:
TRB

Gene Alias:
T cell receptor beta locus; tcr beta f1; TCRB; TRB; TRB@

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6957

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

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Invitrogen

25-580-882

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Antigen:
TCR DO11.10

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P01849

Gene Symbols:
Tcra

Immunogen:
__

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
KJ1-26 (KJ126, KJI-26, KJI26)

Conjugate:
PE-Cyanine7

Gene:
Tcra

Gene Alias:
D011.10; T cell receptor alpha chain; Tcra; Tcralpha

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21473

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

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Invitrogen

25-581-282

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Antigen:
TCR V alpha 2

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a λ

Applications:
Flow Cytometry

Clone:
B20.1

Conjugate:
PE-Cyanine7

Gene:
__

Gene Alias:
TCRVA; TCRVA2; V alpha 2; V alpha-2 TCR; Va 2; Va2; Valpha 2; Valpha2

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

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Fischer Scientific

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Antigen:
Granzyme A

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P11032

Gene Symbols:
GZMA

Immunogen:
__

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
GzA-3G8.5

Conjugate:
PE-Cyanine7

Gene:
GZMA

Gene Alias:
Autocrine thymic lymphoma granzyme-like serine protease; AW494114; BLT esterase; CTL tryptase; CTLA3; CTLA-3; Cytotoxic T-lymphocyte proteinase 1; Cytotoxic T-lymphocyte-associated serine esterase-3; fragmentin-1; granzyme 1; granzyme A; Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease); granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3); Granzyme-1; GZMA; H factor; Hanukah factor; Hanukah factor serine protease); Hanukkah factor; Hf; HFSP; Mtsp-1; SE1; serine esterase 1; t cell-specific serine protease 1; TSP1; TSP-1

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14938

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid