25-985-880

IRF4 Monoclonal Antibody (3E4), PE-Cyanine7, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 25-985-880-Each-of-1 In Stock ₹ 12,320.64

25-985-880 - Each of 1

₹ 12,320.64

In Stock

Quantity

1

Base Price: ₹ 12,320.64

GST (18%): ₹ 2,217.715

Total Price: ₹ 14,538.355

Antigen

IRF4

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q15306, Q64287

Gene Symbols

IRF4

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16364, 3662

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

3E4

Conjugate

PE-Cyanine7

Gene

IRF4

Gene Alias

AI385587; interferon regulatory factor 4; Irf4; IRF-4; LSIRF; Lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1; NF-EM5; PU.1 interaction partner; Sfpi1/PU.1 interaction partner; SHEP8; Spip; Transcriptional activator PIP

Host Species

Rat

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1 κ

Related Products

Img

Fischer Scientific

25-537-541

--

Img

Fischer Scientific

25-537-542

--

Img

Fischer Scientific

25-611-980

--

Img

Fischer Scientific

25-611-982

--

Img

Fischer Scientific

25-027-941

--

Img

Fischer Scientific

25-108-480

--

Img

Fischer Scientific

25-108-482

--

Img

Fischer Scientific

200089013

Mouse Monoclonal Antibody...

Description

  • Description: The monoclonal antibody 3E4 reacts with human and mouse interferon regulatory factor 4 (IRF4)
  • IRF4 is a 52 kDa transcription factor with roles in B cell, T cell and macrophage function
  • In B cells, IRF4 is highly expressed in mature plasma cells and plays a crucial role in their differentiation
  • IRF4 has been shown to interact with PU.1 and control the transcription of many B cell-specific genes including Prdm1, which encodes Blimp1
  • In T cells, IRF4 has been implicated in regulatory T (Treg), Th2, Th9 and Th17 cell development and function
  • This transcription factor is upregulated upon T cell activation and is expressed in mature T cells
  • Studies have shown that IRF4 directly induces Blimp1 expression in Tregs, leading to IL-10 expression
  • IRF4 has also been demonstrated to be involved in macrophage polarization and regulation
  • Lastly, in addition to its roles in normal immune function, IRF4 expression has been reported to be upregulated in many blood-related cancers
  • Applications Reported: This 3E4 antibody has been reported for use in intracellular staining followed by flow cytometric analysis
  • Applications Tested: This 3E4 antibody has been tested by intracellular staining and flow cytometric analysis of stimulated normal human peripheral blood cells using the Foxp3/Transcription Factor Buffer Set (cat 00-5523) and protocol
  • IRF4 Monoclonal antibody specifically detects IRF4 in Human, Mouse samples
  • It is validated for Flow Cytometry.

Compare Similar Items

Show Difference

Img

Fischer Scientific

25-985-880

--


Antigen:
IRF4

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q15306, Q64287

Gene Symbols:
IRF4

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16364, 3662

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
3E4

Conjugate:
PE-Cyanine7

Gene:
IRF4

Gene Alias:
AI385587; interferon regulatory factor 4; Irf4; IRF-4; LSIRF; Lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1; NF-EM5; PU.1 interaction partner; Sfpi1/PU.1 interaction partner; SHEP8; Spip; Transcriptional activator PIP

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Invitrogen

25-986-342

--


Antigen:
Phospho-NFkB p65 (Ser529)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q04206

Gene Symbols:
RELA

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5970

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
B33B4WP

Conjugate:
PE-Cyanine7

Gene:
RELA

Gene Alias:
avian reticuloendotheliosis viral (v-rel) oncogene homolog A; EBP-1; I79_021812; MGC131774; NF KB; NFkappaB p65; nf-kappa-b p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NF-kB p65 subunit; nfkb rela; NFKB1; nfkb3; NFkB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit p65; nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; putative transcription factor p65 homolog; REL A; rel1; rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; Xrel1; xrela

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Invitrogen

25-988-242

--


Antigen:
GARP

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q14392

Gene Symbols:
LRRC32

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2615

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
G14D9

Conjugate:
PE-Cyanine7

Gene:
LRRC32

Gene Alias:
AI426318; D11S833E; D11S833Eh; D7H11S833E; EG434215; Garp; garpin; Glycoprotein A repetitions predominant; leucine rich repeat containing 32; leucine-rich repeat-containing protein 32; Lrrc32; Transforming growth factor beta activator LRRC32

Host Species:
Rat

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Invitrogen

25-997-042

--


Antigen:
Kappa Light Chain

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P01601, P01602, P01834, P0DOX7

Gene Symbols:
IGK, IGKC, IGKV1-5, IGKV1D-16

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
28299, 28901, 3514, 50802

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
TB28-2

Conjugate:
PE-Cyanine7

Gene:
IGK

Gene Alias:
D4Mit8, HCAK1, ig kappa chain c region, Igk, Igk@, Igkc, Igk-C, IGKCD, IGKV, IGKV15, IGKV1-5, Immunoglobulin K, immunoglobulin kappa chain complex, immunoglobulin kappa constant, immunoglobulin kappa light chain, immunoglobulin kappa locus, immunoglobulin kappa variable 1-5, kappa, Kappa LC, Km, L12, L12a, LOC500183, similar to NGF-binding Ig light chain, V1

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ