35-589-382

KLRG1 Monoclonal Antibody (2F1), PE-Cyanine5.5, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 35-589-382-Each-of-1 In Stock ₹ 33,282.84

35-589-382 - Each of 1

₹ 33,282.84

In Stock

Quantity

1

Base Price: ₹ 33,282.84

GST (18%): ₹ 5,990.911

Total Price: ₹ 39,273.751

Antigen

KLRG1

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.

O88713

Gene Symbols

Klrg1

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

50928

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

2F1

Conjugate

PE-Cyanine5.5

Gene

Klrg1

Gene Alias

2F1, 2F1-Ag, CLEC15A, C-type lectin domain family 15 member A, C-type lectin domain family 15, member A, ITIM-containing receptor MAFA-L, killer cell lectin like receptor G1, killer cell lectin-like receptor subfamily G member 1, killer cell lectin-like receptor subfamily G, member 1, Klrg1, Mafa, MAFA-2F1, MAFAL, MAFA-L, MAFA-LIKE, MAFA-like receptor, Mast cell function-associated antigen, mast cell function-associated antigen (ITIM-containing), mast cell function-associated antigen 2F1, natural killer cell receptor

Host Species

Syrian Hamster

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Description: This 2F1 monoclonal antibody reacts with the mouse Killer cell Lectin-like Receptor G1 (KLRG1), also known as Mast cell Function-associated Antigen (MAFA)
  • KLRG1 is a homodimer of glycosylated 30-38 kDa subunits and contains a cytoplasmic motif similar to the immunoreceptor tyrosine-based inhibitory motif (ITIM)
  • Rat MAFA was identified as an antigen specific to rat mast cells; however, the expression of mouse KLRG1/MAFA using 2F1 has not been detected on the surface of mouse mast cell lines, bone marrow-derived mast cells, or peritoneal mast cells
  • This antigen is expressed on approximately one-third of mouse NK cells and a subset of T cells
  • MHC class I molecules regulate KLRG1 via interactions with class I-specific inhibitory Ly49 molecules and SHP-1 signaling
  • Although KLRG1 and Ly49 are both lectin-like inhibitory receptors that are regulated by class I MHC expression, the effects of this on cell surface expression of these molecules are opposing, and the underlying regulatory mechanisms distinct
  • Applications Reported: This 2F1 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 2F1 antibody has been tested by flow cytometric analysis of mouse splenocytes
  • This may be used at less than or equal to 0.25 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric member of the lectin-like type 2 transmembrane receptor family whose members contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains
  • These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1
  • KLRG1 is an inhibitory receptor that is expressed on natural killer (NK) cells and certain T cells
  • NK cells are involved in the lysis of tumor cells and virus-infected cells, and mediate humoral and cell-mediated immune responses.

Compare Similar Items

Show Difference

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Invitrogen

35-589-382

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Antigen:
KLRG1

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.:
O88713

Gene Symbols:
Klrg1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
50928

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
2F1

Conjugate:
PE-Cyanine5.5

Gene:
Klrg1

Gene Alias:
2F1, 2F1-Ag, CLEC15A, C-type lectin domain family 15 member A, C-type lectin domain family 15, member A, ITIM-containing receptor MAFA-L, killer cell lectin like receptor G1, killer cell lectin-like receptor subfamily G member 1, killer cell lectin-like receptor subfamily G, member 1, Klrg1, Mafa, MAFA-2F1, MAFAL, MAFA-L, MAFA-LIKE, MAFA-like receptor, Mast cell function-associated antigen, mast cell function-associated antigen (ITIM-containing), mast cell function-associated antigen 2F1, natural killer cell receptor

Host Species:
Syrian Hamster

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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Fischer Scientific

35-592-080

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Antigen:
iNOS

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P29477

Gene Symbols:
Nos2

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18126

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
CXNFT

Conjugate:
PE-Cyanine5.5

Gene:
Nos2

Gene Alias:
Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Fischer Scientific

35-592-082

--


Antigen:
iNOS

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P29477

Gene Symbols:
Nos2

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18126

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
CXNFT

Conjugate:
PE-Cyanine5.5

Gene:
Nos2

Gene Alias:
Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Invitrogen

35-592-182

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Antigen:
TER-119

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
0

Gene Symbols:
Ly76

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
104231

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
TER-119

Conjugate:
PE-Cyanine5.5

Gene:
Ly76

Gene Alias:
Ly76; Ly-76; TER119

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b κ