50-109-09
Ly-49A Monoclonal Antibody (A1 (Ly49A)), PE, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-109-09-Each-of-1 | In Stock | ₹ 28,405.92 |
50-109-09 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 28,405.92
GST (18%): ₹ 5,113.066
Total Price: ₹ 33,518.986
Antigen
Ly-49A
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P20937
Gene Symbols
Klra1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16627
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
A1 (Ly49A)
Conjugate
PE
Gene
Klra1
Gene Alias
A1; CH29-493D4.3; class I MHC receptor KLRA22; killer cell lectin like receptor A1, pseudogene; killer cell lectin-like receptor 2; killer cell lectin-like receptor, subfamily A, member 1; killer cell lectin-like receptor, subfamily A, member 2; KLRA#; KLRA1; KLRA1P; Klra2; Klra22; KLRAP1; Ly49; Ly49 inhibitory receptor 8; Ly49a; ly-49a; Ly49i8; LY49L; Ly-49L; Ly49o<129>; Ly49v; lymphocyte antigen 49a; natural killer cell receptor Ly49A; novel killer cell lectin-like receptor subfamily A protein; t lymphocyte antigen A1; T-cell surface glycoprotein YE1/48
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a
Related Products
Description
- Description: This A1 monoclonal antibody reacts with Ly49A, a 44-kDa member of the Ly49 family of type II transmembrane receptors expressed on natural killer (NK) cells
- This receptor is present as a disulfide-linked homodimer with C-type lectin extracellular domains
- An inhibitory receptor, Ly49A binds MHC class I molecules, such as H-2Dd, H-2Dk, and H-2DP, to inhibit NK-mediated cytotoxicity by triggering phosphorylation of its ITIM domain and recruitment of SHP-1 and SHP-2
- Ly49A is expressed on DX5+CD3- NK cells and DX5+CD3+ NK T cells, as well as on a population of memory CD8+ T cells in C57BL/6, C57BL/10, and B10 congenic mice
- Applications Reported: This A1 (Ly49A) antibody has been reported for use in flow cytometric analysis
- Applications Tested: This A1 (Ly49A) antibody has been tested by flow cytometric analysis on C57Bl/6 splenocytes
- This can be used at less than or equal to 0.5 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
- Filtration: 0.2 μm post-manufacturing filtered
- Ly49A is a gene that encodes a protein expressed on the surface of natural killer cells, which is involved in recognizing and eliminating virally infected or cancerous cells
- It is located on chromosome 6 and is part of a larger family of genes that encode for similar receptors
- The Ly49A protein interacts with a variety of ligands, including certain viruses and tumor cells, and is involved in regulating the activation and function of natural killer cells
- Mutations or variations in the Ly49A gene have been associated with various diseases and conditions, including autoimmune disorders and cancer.
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Show Difference
Antigen: Ly-49A
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P20937
Gene Symbols: Klra1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16627
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: A1 (Ly49A)
Conjugate: PE
Gene: Klra1
Gene Alias: A1; CH29-493D4.3; class I MHC receptor KLRA22; killer cell lectin like receptor A1, pseudogene; killer cell lectin-like receptor 2; killer cell lectin-like receptor, subfamily A, member 1; killer cell lectin-like receptor, subfamily A, member 2; KLRA#; KLRA1; KLRA1P; Klra2; Klra22; KLRAP1; Ly49; Ly49 inhibitory receptor 8; Ly49a; ly-49a; Ly49i8; LY49L; Ly-49L; Ly49o<129>; Ly49v; lymphocyte antigen 49a; natural killer cell receptor Ly49A; novel killer cell lectin-like receptor subfamily A protein; t lymphocyte antigen A1; T-cell surface glycoprotein YE1/48
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a
Antigen:
Ly-49A
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P20937
Gene Symbols:
Klra1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16627
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
A1 (Ly49A)
Conjugate:
PE
Gene:
Klra1
Gene Alias:
A1; CH29-493D4.3; class I MHC receptor KLRA22; killer cell lectin like receptor A1, pseudogene; killer cell lectin-like receptor 2; killer cell lectin-like receptor, subfamily A, member 1; killer cell lectin-like receptor, subfamily A, member 2; KLRA#; KLRA1; KLRA1P; Klra2; Klra22; KLRAP1; Ly49; Ly49 inhibitory receptor 8; Ly49a; ly-49a; Ly49i8; LY49L; Ly-49L; Ly49o<129>; Ly49v; lymphocyte antigen 49a; natural killer cell receptor Ly49A; novel killer cell lectin-like receptor subfamily A protein; t lymphocyte antigen A1; T-cell surface glycoprotein YE1/48
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a
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