3851559
Rab5 Mouse, Unlabeled, Clone: 1, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Rab5
Concentration
250μg/mL
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Cell Biology
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype
IgG2a
Purification Method
Affinity Purified
Clone
1
Applications
Western Blot
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Canine, Human
Immunogen
Human Rab5 aa. 1-215
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
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Description
- Rab5 is a low molecular weight GTP-binding protein that plays a role in endocytic vesicle traffic
- Like other Rab proteins, Rab5 has C-terminal cysteine residues that are post translationally modified by geranylgeranylation which is critical for its membrane targeting
- Rab5 is associated with early endosome and plasma membranes and evidence suggests that Rab5 regulates early endosome fusion
- The GTP/GDP cycle controls shuttling of Rab proteins between the cytosol and membranes
- In vitro, Rab5 proteins are removed from membranes by a GDP dissociation inhibitor protein (rabGDI) which leads to the formation of a cytosolic Rab5-rabGDI complex
- Rab5 may insert into membranes by a multistep process in a which a transient GDP-Rab5 intermediate is formed and converted into GTP-Rab5 that subsequently enters the acceptor membrane and releases rabGDI into the cytosol
- Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Compare Similar Items
Show Difference
Antigen: Rab5
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG2a
Purification Method: Affinity Purified
Clone: 1
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Canine, Human
Immunogen: Human Rab5 aa. 1-215
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Rab5
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG2a
Purification Method:
Affinity Purified
Clone:
1
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Canine, Human
Immunogen:
Human Rab5 aa. 1-215
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: NAT1
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 35
Applications: Immunofluorescence, Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Bovine, Canine, Human, Mouse, Rat
Immunogen: Human NAT1 aa. 672-830
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
NAT1
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
35
Applications:
Immunofluorescence, Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Bovine, Canine, Human, Mouse, Rat
Immunogen:
Human NAT1 aa. 672-830
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: RONα
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: __
Isotype: IgG2b
Purification Method: Affinity Purified
Clone: 29
Applications: __
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Canine, Frog, Human, Mouse, Rat
Immunogen: Human RONα aa. 40-224
Primary or Secondary: Primary
Content And Storage: __
Antigen:
RONα
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
__
Isotype:
IgG2b
Purification Method:
Affinity Purified
Clone:
29
Applications:
__
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Canine, Frog, Human, Mouse, Rat
Immunogen:
Human RONα aa. 40-224
Primary or Secondary:
Primary
Content And Storage:
__
Antigen: Carboxypeptidase E
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 35
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human, Mouse, Rat
Immunogen: Human Carboxypeptidase E aa. 49-200
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Carboxypeptidase E
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
35
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rat
Immunogen:
Human Carboxypeptidase E aa. 49-200
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.