3855802

P-Cadherin Mouse, Unlabeled, Clone: 56, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

P-Cadherin

Concentration

250μg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype

IgG1

Purification Method

Affinity Purified

Clone

56

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Human, Rat

Immunogen

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

Description

  • Cadherins are a family of transmembrane glycoproteins involved in the Ca 2 + -dependent cell-cell adhesion that occurs in many tissues
  • Cadherins are similar in their domain structure, Ca 2 + and protease sensitivity, and molecular weight
  • However, these proteins have distinct tissue expression patterns and immunological reactivities
  • P-Cadherin is localized in placenta while E-Cadherin and N-Cadherin are found in epithelial and neural tissues, respectively
  • P-Cadherin is an 829 amino acid polypeptide with a putative signal peptide and precursor region, an extracellular domain containing several internal repeats, and a highly hydrophobic transmembrane region
  • The cytoplasmic domain provides a link to the cytoskeleton through the associated catenin proteins
  • Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

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Mouse Monoclonal Antibody...


Antigen:
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Concentration:
250μg/mL

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Mouse

Research Discipline:
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Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
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Purification Method:
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Clone:
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Applications:
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Conjugate:
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Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

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Store undiluted at -20°C.

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Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

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