3855824

γ-Catenin Mouse, Unlabeled, Clone: 15, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

γ-Catenin

Concentration

250μg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype

IgG2a

Purification Method

Affinity Purified

Clone

15

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Canine, Chicken, Human, Mouse, Rat

Immunogen

Human γ-Catenin aa. 553-738

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • γ-Catenin (plakoglobin) was identified as a compenent of desmosomes where it associates with desmoglein
  • γ-Catenin and β-Catenin are closely related proteins that have significant homology with the Drosophila armadillo protein
  • In addition to complexing with E-Cadherin, γ-Catenin and β-Catenin have been observed in association with the intracellular domain of N-Cadherin
  • It has been proposed that one molecule of α-Catenin and at least one molecule of β-Catenin and γ-Catenin simultaneously bind to a single cadherin molecule
  • A 19 amino acid sequence of desmoglein (Dsg1) was found to be critical for binding of γ-Catenin
  • This region has significant homology to the catenin-binding domain of classical cadherins, thus suggesting a common mechanism for γ-Catenin localization at both adherens junctions and desmosomes
  • Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

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Show Difference

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3855824

Mouse Monoclonal Antibody...


Antigen:
γ-Catenin

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG2a

Purification Method:
Affinity Purified

Clone:
15

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Chicken, Human, Mouse, Rat

Immunogen:
Human γ-Catenin aa. 553-738

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
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Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG2a

Purification Method:
Affinity Purified

Clone:
10

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Chicken, Drosophila, Human, Mouse, Rat

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary:
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Content And Storage:
Store undiluted at -20°C.

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Concentration:
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Host Species:
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Research Discipline:
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Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
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Clone:
69

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary:
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Content And Storage:
Store undiluted at -20°C.

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Antigen:
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Concentration:
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Classification:
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Host Species:
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Research Discipline:
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Formulation:
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Isotype:
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Purification Method:
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Clone:
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Applications:
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Conjugate:
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Regulatory Status:
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Target Species:
Canine, Chicken, Human, Mouse, Rat

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.