3856109

Paxillin Mouse, Unlabeled, Clone: 165, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Paxillin

Concentration

250μg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype

IgG1

Purification Method

Affinity Purified

Clone

165

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Canine, Chicken, Human, Mouse, Rat

Immunogen

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

Description

  • Paxillin, a focal adhesion protein, is a substrate for several tyrosine kinases such as src, FAK, and p120BRC/ABL
  • The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion
  • This is consisent with the possibility that paxillin is involved in the regulation of cell morphology
  • Additionally, because of its SH3 binding domain, paxillin associates tightly with FAK and Crk in an extracellular matrix-independent manner
  • Paxillin was initially detected in fibroblasts, and its phosphorylation may be important during neurite extension during differentiation
  • This antibody is routinely tested by western blot analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

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3856109

Mouse Monoclonal Antibody...


Antigen:
Paxillin

Concentration:
250μg/mL

Classification:
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Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Clone:
165

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Chicken, Human, Mouse, Rat

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Concentration:
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Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

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Purification Method:
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Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

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Store undiluted at -20°C.

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