3856115

ROCK-II Mouse, Unlabeled, Clone: 21, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

ROCK-II

Concentration

250μg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype

IgG1

Purification Method

Affinity Purified

Description

ROKα

Clone

21

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Canine, Human, Mouse, Rat

Immunogen

Rat ROKα aa. 567-718

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • Activity of the GTP-binding proteins is regulated by GAPs, that accelerate binding, and GTPases, that enhance the rate of GTP hydrolysis (Ras, Rho, cdc42Hs, and Rac)
  • The isoforms of Rho, a small GTP-binding protein, regulate cellular processes such as the formation of the stress fibers, lamelipodia, and filopodia
  • ROKα (RhoA-binding kinase) is a Ser/Thr protein kinase that interects with the GTP-binding form of RhoA
  • Like RhoA, ROKα localizes at the cellular margins and colocalizes with acti filaments
  • The ROKα gene encodes a protein of 1302 amino acids with homology to the human myotonic kinase
  • Although ROKα binds to GTP-RhoA, it is not yet clear whether this interaction induces the kinase activity of ROKα
  • Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

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Fischer Scientific

3856115

Mouse Monoclonal Antibody...


Antigen:
ROCK-II

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Description:
ROKα

Clone:
21

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Human, Mouse, Rat

Immunogen:
Rat ROKα aa. 567-718

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
PKA RIIβ

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Description:
__

Clone:
45

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Chicken, Human, Mouse, Rat

Immunogen:
Human PKA RIIβ, aa 1-418

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
PKA RIIβ

Concentration:
250μg/mL

Classification:
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Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Description:
__

Clone:
45

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Chicken, Human, Mouse, Rat

Immunogen:
Human PKA RIIβ, aa 1-418

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
SMN

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Description:
Survival Motor Neuron

Clone:
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Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Human, Mouse, Rat

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.