39-770-0
IkB alpha Monoclonal Antibody (ZI002), Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 39-770-0-Each-of-1 | In Stock | ₹ 34,224.00 |
39-770-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,224.00
GST (18%): ₹ 6,160.32
Total Price: ₹ 40,384.32
Antigen
IkB alpha
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.
P25963, Q9Z1E3
Gene Symbols
NFKBIA
Immunogen
Synthetic peptide derived from the C-terminal region of the human I-kappa-B-alpha protein
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1 κ
Applications
ELISA, Immunocytochemistry, Western Blot
Clone
ZI002
Conjugate
Unconjugated
Gene
NFKBIA
Gene Alias
AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18035, 4792
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- IkB-alpha is a 40 kDa protein that functions to inhibit NF- kappaB activity
- The inhibition occurs via protein-protein interaction between I kappaB proteins and NF- kappaB dimers in the cytosol
- The interaction of I kappa B-alpha with NF- kappaB masks the nuclear localization sequence of NF- kappaB, preventing NF- kappaB translocation to the nucleus
- A variety of stimuli can activate gene expression by liberating NF- kappaB through the degradation of I kappaB alpha
- These stimuli include the proinflammatory cytokines TNF- alpha and IL-1 beta, chemokines, PMA, growth factors, LPS, UV irradiation, viral infection, as well as various chemical and physical stresses
- In humans, the gene is located on the q arm of chromosome 14
- Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in targeted degradation of IkB
- IkB kinase alpha (IKK alpha), previously designated CHUK, interacts with IkB-alpha and specifically phosphorylates IkB-alpha on the sites that trigger its degradation Serines 32 and 36
- IKK alpha appears to be critical for NFkB activation in response to proinflammatory cytokines
- Phosphorylation of IkB by IKK alpha is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1
- The functional IKK complex contains three subunits, IKK alpha, IKK beta and IKK gamma, and each appear to make essential contributions to IkB phosphorylation.
Compare Similar Items
Show Difference
Antigen: IkB alpha
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.: P25963, Q9Z1E3
Gene Symbols: NFKBIA
Immunogen: Synthetic peptide derived from the C-terminal region of the human I-kappa-B-alpha protein
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1 κ
Applications: ELISA, Immunocytochemistry, Western Blot
Clone: ZI002
Conjugate: Unconjugated
Gene: NFKBIA
Gene Alias: AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 18035, 4792
Content And Storage: -20°C
Form: Liquid
Antigen:
IkB alpha
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.:
P25963, Q9Z1E3
Gene Symbols:
NFKBIA
Immunogen:
Synthetic peptide derived from the C-terminal region of the human I-kappa-B-alpha protein
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
ELISA, Immunocytochemistry, Western Blot
Clone:
ZI002
Conjugate:
Unconjugated
Gene:
NFKBIA
Gene Alias:
AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
18035, 4792
Content And Storage:
-20°C
Form:
Liquid
Antigen: CDX2
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.: Q99626
Gene Symbols: CDX2
Immunogen: Recombinant full-length human CDX2 protein
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone: ZC007
Conjugate: Unconjugated
Gene: CDX2
Gene Alias: caudal type homeo box 2; caudal type homeo box transcription factor 2; caudal type homeobox 2; caudal type homeobox transcription factor 2; caudal-type homeobox protein 2; CDX2; Cdx-2; CDX2/AS; CDX3; CDX-3; HGNC:1806; homeobox protein CDX-2; homeobox protein miniCDX2; homeobox transcription factor
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1045
Content And Storage: -20°C
Form: Liquid
Antigen:
CDX2
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.:
Q99626
Gene Symbols:
CDX2
Immunogen:
Recombinant full-length human CDX2 protein
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone:
ZC007
Conjugate:
Unconjugated
Gene:
CDX2
Gene Alias:
caudal type homeo box 2; caudal type homeo box transcription factor 2; caudal type homeobox 2; caudal type homeobox transcription factor 2; caudal-type homeobox protein 2; CDX2; Cdx-2; CDX2/AS; CDX3; CDX-3; HGNC:1806; homeobox protein CDX-2; homeobox protein miniCDX2; homeobox transcription factor
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1045
Content And Storage:
-20°C
Form:
Liquid
Antigen: GAD65
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.: P48320, Q05329, Q05683
Gene Symbols: GAD2
Immunogen: Recombinant protein corresponding to the N-terminal region of the human GAD65 protein
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone: ZG002
Conjugate: Unconjugated
Gene: GAD2
Gene Alias: 6330404F12Rik; 65 kDa glutamic acid decarboxylase; GAD(65); GAD2; Gad-2; GAD65; GAD-65; Glutamate decarboxylase 2; Glutamate decarboxylase 2 (islet); glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); glutamate decarboxylase 65 kDa isoform; Glutamate decarboxylase-2 (pancreas); glutamic acid decarboxylase 2; glutamic acid decarboxylase 65; MGC161605; MGC161607; RP11-420F12.2
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 14417, 24380, 2572
Content And Storage: -20°C
Form: Liquid
Antigen:
GAD65
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.:
P48320, Q05329, Q05683
Gene Symbols:
GAD2
Immunogen:
Recombinant protein corresponding to the N-terminal region of the human GAD65 protein
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone:
ZG002
Conjugate:
Unconjugated
Gene:
GAD2
Gene Alias:
6330404F12Rik; 65 kDa glutamic acid decarboxylase; GAD(65); GAD2; Gad-2; GAD65; GAD-65; Glutamate decarboxylase 2; Glutamate decarboxylase 2 (islet); glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); glutamate decarboxylase 65 kDa isoform; Glutamate decarboxylase-2 (pancreas); glutamic acid decarboxylase 2; glutamic acid decarboxylase 65; MGC161605; MGC161607; RP11-420F12.2
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
14417, 24380, 2572
Content And Storage:
-20°C
Form:
Liquid
Antigen: STRO-1
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.1% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: CD34+ human bone marrow cells
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgM
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Clone: STRO-1
Conjugate: Unconjugated
Gene: __
Gene Alias: STRO1
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20°C
Form: Liquid
Antigen:
STRO-1
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.1% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
CD34+ human bone marrow cells
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgM
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
STRO-1
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
STRO1
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20°C
Form:
Liquid