46-680-182
IkB zeta Monoclonal Antibody (LK2NAP), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 46-680-182-Each-of-1 | In Stock | ₹ 35,764.08 |
46-680-182 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,764.08
GST (18%): ₹ 6,437.534
Total Price: ₹ 42,201.614
Antigen
IkB zeta
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q9EST8
Gene Symbols
NFKBIZ
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
80859
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
LK2NAP
Conjugate
PerCP-eFluor 710
Gene
NFKBIZ
Gene Alias
AA408868; FLJ30225; FLJ34463; Ikappa B-zeta variant 3; ikappaBzeta; I-kappa-B-zeta; IkappaB-zeta; IKBZ; ikB-zeta; IL-1 inducible nuclear ankyrin-repeat protein; INAP; Mail; molecule possessing ankyrin repeats induced by lipopolysaccharide; molecule possessing ankyrin-repeats induced by lipopolysaccharide; NF-kappa-B inhibitor zeta; NFKB inhibitor zeta; NFKBIZ; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta; OTTHUMP00000214340; RGD1310834
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The LK2NAP monoclonal antibody reacts with mouse IkB zeta (INAP, MAIL)
- IkBz is a member of the IkB family of cytoplasmic proteins and transcription factors and also shares structural homology with Bcl-3
- It is induced in monocytes, macrophages and B cells in response to TLR and IL-1R signaling
- In NK cells, IkBz is rapidly upregulated in response to IL-12 and IL-18 and is necessary for production of IFN gamma
- In T cells, IkBz is not necessary for IFN gamma and IL-4 production by Th1 and Th2 cells, respectively
- However in Th17 cells, IkBz acts in concert with RORa and RORgt to upregulate IL-17A, IL-17F, IL-21, IL-22 and IL-23R expression
- Applications Reported: This LK2NAP antibody has been reported for use in intracellular staining followed by flow cytometric analysis
- Applications Tested: This LK2NAP antibody has been tested by intracellular staining and flow cytometric analysis of LPS-activated mouse splenocytes using the Foxp3/Transcription Factor Staining Buffer Set (cat
- 00-5523) and protocol
- This can be used at less than or equal to 0.125 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- I-kappa-B-zeta (also known as MAIL and INAP) is an ankyrin-repeat-containing nuclear protein that is highly homologous to the IkappaB family member Bcl-3
- Transcription of IkappaBzeta is upregulated by stimulation with TLR ligands, IL-1 and IL-6 in cultured B-lymphocytes and monocytes/macrophages, but only faintly so in T-lymphocytes, fibroblasts, and endothelial cells
- IkappaB-zeta preferentially associates with the NF-kappaB subunit p50 rather than p65 and recombinant IkappaB-zeta proteins inhibit the DNA binding of the p65/p50 heterodimer and the p50/p50 homodimer.
Compare Similar Items
Show Difference
Antigen: IkB zeta
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9EST8
Gene Symbols: NFKBIZ
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 80859
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: LK2NAP
Conjugate: PerCP-eFluor 710
Gene: NFKBIZ
Gene Alias: AA408868; FLJ30225; FLJ34463; Ikappa B-zeta variant 3; ikappaBzeta; I-kappa-B-zeta; IkappaB-zeta; IKBZ; ikB-zeta; IL-1 inducible nuclear ankyrin-repeat protein; INAP; Mail; molecule possessing ankyrin repeats induced by lipopolysaccharide; molecule possessing ankyrin-repeats induced by lipopolysaccharide; NF-kappa-B inhibitor zeta; NFKB inhibitor zeta; NFKBIZ; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta; OTTHUMP00000214340; RGD1310834
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
IkB zeta
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9EST8
Gene Symbols:
NFKBIZ
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
80859
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
LK2NAP
Conjugate:
PerCP-eFluor 710
Gene:
NFKBIZ
Gene Alias:
AA408868; FLJ30225; FLJ34463; Ikappa B-zeta variant 3; ikappaBzeta; I-kappa-B-zeta; IkappaB-zeta; IKBZ; ikB-zeta; IL-1 inducible nuclear ankyrin-repeat protein; INAP; Mail; molecule possessing ankyrin repeats induced by lipopolysaccharide; molecule possessing ankyrin-repeats induced by lipopolysaccharide; NF-kappa-B inhibitor zeta; NFKB inhibitor zeta; NFKBIZ; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta; OTTHUMP00000214340; RGD1310834
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: ROR gamma (t)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: P51449, P51450
Gene Symbols: Rorc
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19885, 6097, 717052
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: AFKJS-9
Conjugate: PerCP-eFluor 710
Gene: Rorc
Gene Alias: EGK_01272, IMD42, MGC129539, NR1F3, nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, nuclear receptor subfamily 1 group F member 3, RAR related orphan receptor C, RAR-related orphan nuclear receptor variant 2, RAR-related orphan receptor C, RAR-related orphan receptor C, isoform a, RAR-related orphan receptor gamma, retinoic acid-binding receptor gamma, retinoid-related orphan receptor gamma, retinoid-related orphan receptor-gamma, ROR Gamma, ROR gamma t, Rorc, Rorg, RORgamma, RORgt, RP11-98D18.11-001, RZRG, RZR-GAMMA, Thor, Thymus orphan receptor, TOR
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rhesus Monkey
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
ROR gamma (t)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
P51449, P51450
Gene Symbols:
Rorc
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19885, 6097, 717052
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
AFKJS-9
Conjugate:
PerCP-eFluor 710
Gene:
Rorc
Gene Alias:
EGK_01272, IMD42, MGC129539, NR1F3, nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, nuclear receptor subfamily 1 group F member 3, RAR related orphan receptor C, RAR-related orphan nuclear receptor variant 2, RAR-related orphan receptor C, RAR-related orphan receptor C, isoform a, RAR-related orphan receptor gamma, retinoic acid-binding receptor gamma, retinoid-related orphan receptor gamma, retinoid-related orphan receptor-gamma, ROR Gamma, ROR gamma t, Rorc, Rorg, RORgamma, RORgt, RP11-98D18.11-001, RZRG, RZR-GAMMA, Thor, Thymus orphan receptor, TOR
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: ROR gamma (t)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: P51449, P51450
Gene Symbols: Rorc
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19885, 6097, 717052
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: AFKJS-9
Conjugate: PerCP-eFluor 710
Gene: Rorc
Gene Alias: EGK_01272, IMD42, MGC129539, NR1F3, nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, nuclear receptor subfamily 1 group F member 3, RAR related orphan receptor C, RAR-related orphan nuclear receptor variant 2, RAR-related orphan receptor C, RAR-related orphan receptor C, isoform a, RAR-related orphan receptor gamma, retinoic acid-binding receptor gamma, retinoid-related orphan receptor gamma, retinoid-related orphan receptor-gamma, ROR Gamma, ROR gamma t, Rorc, Rorg, RORgamma, RORgt, RP11-98D18.11-001, RZRG, RZR-GAMMA, Thor, Thymus orphan receptor, TOR
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rhesus Monkey
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
ROR gamma (t)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
P51449, P51450
Gene Symbols:
Rorc
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19885, 6097, 717052
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
AFKJS-9
Conjugate:
PerCP-eFluor 710
Gene:
Rorc
Gene Alias:
EGK_01272, IMD42, MGC129539, NR1F3, nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, nuclear receptor subfamily 1 group F member 3, RAR related orphan receptor C, RAR-related orphan nuclear receptor variant 2, RAR-related orphan receptor C, RAR-related orphan receptor C, isoform a, RAR-related orphan receptor gamma, retinoic acid-binding receptor gamma, retinoid-related orphan receptor gamma, retinoid-related orphan receptor-gamma, ROR Gamma, ROR gamma t, Rorc, Rorg, RORgamma, RORgt, RP11-98D18.11-001, RZRG, RZR-GAMMA, Thor, Thymus orphan receptor, TOR
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: IL-23 p19
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9EQ14
Gene Symbols: IL23A
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 83430
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: fc23cpg
Conjugate: PerCP-eFluor 710
Gene: IL23A
Gene Alias: il 23; IL 23 A; IL12B; Il-12b; Il12p40; Il-12p40; il23; IL-23; IL-23 subunit alpha; IL23A; IL-23A; IL-23-A; IL23P19; IL-23p19; ILN; Interleukin; interleukin 12B; interleukin 23 p19 subunit; interleukin 23 subunit alpha; interleukin 23, alpha subunit p19; interleukin-23 subunit alpha; Interleukin-23 subunit p19; interleukin-six, G-CSF related factor; JKA3 induced upon T-cell activation; MGC79388; P19; p40; RP23-388G23.1; SGRF; UNQ2498/PRO5798
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
IL-23 p19
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9EQ14
Gene Symbols:
IL23A
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
83430
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
fc23cpg
Conjugate:
PerCP-eFluor 710
Gene:
IL23A
Gene Alias:
il 23; IL 23 A; IL12B; Il-12b; Il12p40; Il-12p40; il23; IL-23; IL-23 subunit alpha; IL23A; IL-23A; IL-23-A; IL23P19; IL-23p19; ILN; Interleukin; interleukin 12B; interleukin 23 p19 subunit; interleukin 23 subunit alpha; interleukin 23, alpha subunit p19; interleukin-23 subunit alpha; Interleukin-23 subunit p19; interleukin-six, G-CSF related factor; JKA3 induced upon T-cell activation; MGC79388; P19; p40; RP23-388G23.1; SGRF; UNQ2498/PRO5798
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ