3968472

Caveolin 1 Mouse, Unlabeled, Clone: C060, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Caveolin 1

Concentration

250μg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

Clone

C060

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Canine, Human, Mouse, Rabbit, Rat

Isotype

IgM

Purification Method

Affinity Purified

Description

  • Identified as a tyrosine phosphorylated protein in Rous sarcoma virus-transformed chick embryo fibroblasts (CEF), caveolin is now known to be ubiquitously expressed
  • Caveolin (also known as VIP21) localizes to non-clathrin membrane invaginations (caveolae) on the inner surface of the plasma membrane
  • This transmembrane protein plays a structural role in these specializations
  • Caveolin is also present at the trans-Golgi network (TGN) and similar quantities are found in apically and basolaterally destined transport vesicles
  • Caveolin is part of a complex containing glycosylphosphatidylinositol (GPI)-linked molecules and cytoplasmic signaling proteins
  • Caveolin is a transmembrane adaptor molecule that can simultaneously recognize GPI-linked proteins and interact with downstream cytoplasmic signaling molecules, such as c-yes, Annexin II, and hetero-trimeric G proteins
  • Caveolin-1 can generate two forms, α and β, due to alternate splicing of the mRNA
  • Caveolin-1 forms large lipid-binding homo-oligomers which are believed to play a role in caveolae formation
  • It may also function as a scaffolding protein which concentrates and organizes signaling molecules, a role supported by the fact that caveolin-1 interacts directly with inactive Ras and G-protein α subunits
  • Host Species: Mouse Clone: C060 Isotype: IgM Species Reactivity: Human Immunogen: Human Caveolin 1 aa
  • 1-97 Formula Weight [Chemical]: 22kDa Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

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3968472

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Antigen:
Caveolin 1

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Clone:
C060

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Human, Mouse, Rabbit, Rat

Isotype:
IgM

Purification Method:
Affinity Purified

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Rat Monoclonal Antibody...


Antigen:
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Concentration:
0.5mg/mL

Classification:
Monoclonal

Host Species:
Rat

Research Discipline:
Immunology

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
429 (MVCAM.A)

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Target Species:
Mouse

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

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Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
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Mouse

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IgG2a κ

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Affinity Purified

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Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
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Applications:
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Conjugate:
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