3970150

CD8 Mouse anti-Human, APC-H7, Clone: SK1, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD8

Applications

Flow Cytometry

Conjugate

APC-H7

Regulatory Status

RUO

Target Species

Baboon, Cynomolgus, Human, Rhesus Monkey

Immunogen

Human Peripheral Blood T Cells

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

SK1

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Immunology

Formulation

Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Description

CD8α; CD8A; CD8 alpha; Leu2a; MAL; T8; p32

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Description

  • CD8 recognizes the 32kDa a-subunit of a disulfide-linked bimolecular complex
  • The majority of peripheral blood CD8+ T lymphocytes express an a/b heterodimer (Mr 32, 30kDa), while CD8+CD16+ natural killer (NK) lymphocytes and CD8+ T-cell receptor (TCR)-γ/δ+ lymphocytes express a/a homodimer (Mr 30kDa)
  • CD8+TCR-α/β+ lymphocytes can express either an α/α homodimer or α/β heterodimer
  • The CD8 antigenic determinant binds to class I major histocompatibility (MHC) molecules resulting in increased adhesion between the CD8+ T lymphocytes and target cells
  • Binding of the CD8 antigen is coupled to a protein tyrosine kinase p56lck
  • The CD8:p56lck complex can play a role in T-lymphocyte activation through mediation of the interactions between the CD8 antigen and the CD3/TCR complex
  • Host Species: Mouse Clone: SK1 Isotype: IgG1 κ Species Reactivity: Human Immunogen: Human Peripheral Blood T Cells Flow Cytometry

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Fischer Scientific

3970150

Mouse Monoclonal Antibody...


Antigen:
CD8

Applications:
Flow Cytometry

Conjugate:
APC-H7

Regulatory Status:
RUO

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Immunogen:
Human Peripheral Blood T Cells

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
SK1

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Immunology

Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
CD8α; CD8A; CD8 alpha; Leu2a; MAL; T8; p32

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3970166

Mouse Monoclonal Antibody...


Antigen:
CD8

Applications:
Flow Cytometry

Conjugate:
PE-Cyanine5

Regulatory Status:
RUO

Target Species:
Human

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
HIT8A

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
__

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
__

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Antigen:
CD80

Applications:
Flow Cytometry

Conjugate:
Violet Fluor 450 (V450)

Regulatory Status:
RUO

Target Species:
Human

Immunogen:
Human B7-transfected L cells

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
L307.4

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Immunology

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
B7.1; B7-1; Activation B7-1 antigen; B7; BB1; CD28LG; CD28LG1; LAB7

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Rat Monoclonal Antibody...


Antigen:
CD8a

Applications:
Flow Cytometry

Conjugate:
Biotin

Regulatory Status:
RUO

Target Species:
Mouse

Immunogen:
Mouse Thymus / Spleen

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
53-6.7

Classification:
Monoclonal

Host Species:
Rat

Research Discipline:
Immunology

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
Cd8a; CD8 alpha chain; Ly-2; Lyt2; Lyt-2; Ly-35; Ly-B