4542653

Factor XIII A Ab-2 Rabbit Polyclonal Antibody, Epredia™

Obtain accurate, reproducible results in immunohistochemistry and western blotting experiments with Epredia™ Factor XIII A Ab-2, Rabbit Polyclonal Antibody.

Manufacturer: Fischer Scientific

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Antigen

Factor XIII A Ab-2

Classification

Polyclonal

Host Species

Rabbit

Research Discipline

Hematopoietic

Immunogen

Recombinant protein corresponding to A-subunit of coagulation Factor XIII

Primary or Secondary

Primary

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Human

Isotype

IgG

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Description

  • Factor XIII A Ab-2 detects Factor XIII in both reduced and non-reduced forms
  • It does not react with human Factor XIII B-chain or human Factor XII
  • Factor XIII is a Β-globulin found in plasma and is composed of two subunits
  • Factor XIII-A is the catalytic subunit and is a dimmer of M.W
  • 160 kDa
  • Factor XIII is present in plasma as an α2Β2 heterodimer (M.W
  • 320 kDa); whereas in platelets, only the α2 unit exists
  • Factor XIIIa is a dermal dendrocyte marker and shows variable reaction with these types of tumors
  • It can be used for histiocytic phenotyping and has been reported to mark capillary hemangiomas and tumors of the central nervous system
  • Factor XIII has also been used with CD34 to differentiate between dermatofibroma and dermatofibrosarcoma protuberans
  • Host Species: Rabbit Isotype: IgG Species Reactivity: Human
  • Others not known
  • Epitope: Not determined Immunogen: Recombinant protein corresponding to A-subunit of coagulation Factor XIII Molecular Weight: 160 kDa (unreduced dimer); 80 kDa (reduced monomer) Positive Control: Human recombinant Factor XIII A-subunit; Capillary hemangioma, dermatofibroma and placenta Cellular Localization: Cytoplasmic and nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Note: USA: RUO; Int'l: RUO

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Antigen:
Factor XIII A Ab-2

Classification:
Polyclonal

Host Species:
Rabbit

Research Discipline:
Hematopoietic

Immunogen:
Recombinant protein corresponding to A-subunit of coagulation Factor XIII

Primary or Secondary:
Primary

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG

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Antigen:
p504s/AMACR

Classification:
Monoclonal

Host Species:
Rabbit

Research Discipline:
Cancer and Tumor Biology

Immunogen:
Human p504s/AMACR polypeptide

Primary or Secondary:
Primary

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Regulatory Status:
ASR

Target Species:
__

Isotype:
__

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Antigen:
Collagen II Ab-2

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Extracellular Matrix

Immunogen:
A purified preparation of lathyritic type II collagen from embryonic chicken sternum

Primary or Secondary:
Primary

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
__

Regulatory Status:
RUO

Target Species:
Bovine, Chicken, Human, Mouse, Rat

Isotype:
IgG2a κ

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Antigen:
Collagen VII Ab-1

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Extracellular Matrix

Immunogen:
Insoluble fractions of human neonatal foreskin epidermal cells

Primary or Secondary:
Primary

Applications:
Immunofluorescence, Immunohistochemistry (Frozen)

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Bovine, Goat, Guinea Pig, Human, Non-human Primate, Porcine, Sheep

Isotype:
IgG2a κ